Clinical trials: Cerebral Toxoplasmosis
Toxoplasmosis, Cerebral, HIV Infections
A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection
To evaluate pyrimethamine as a prophylactic agent against toxoplasmic encephalitis in individuals who are coinfected with HIV and latent Toxoplasma gondii.
- Trial name
- NCT00000666
- Testing
- Pyrimethamine
- Where
- 16 sites in United States
- Volunteers
- 600 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Toxoplasmic Encephalitis, AIDS
Treatment of Cerebral Toxoplasmosis in HIV/AIDS
Neurological manifestations of Cerebral toxoplasmosis or Toxoplasmic encephalitis (TE) in most advance stage HIV infected patients composed of fever, headache, alteration of consciousness with focal neurological signs/symptoms…
- Trial name
- NCT00367081
- Testing
- TMX-SMX (Bactrim(R)), Pyrimethamine plus Sulfadiazine plus leucoverin
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Toxoplasmosis, Cerebral, HIV Infections
A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS
To collect information on the effectiveness and toxicity of clindamycin plus pyrimethamine and leucovorin calcium for the treatment of acute toxoplasmic encephalitis in adult patients with AIDS.
- Trial name
- NCT00000674
- Testing
- Pyrimethamine, Leucovorin calcium, Clindamycin
- Where
- 13 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Toxoplasmosis, Cerebral, HIV Infections
Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients
To evaluate the effectiveness of pyrimethamine (given with leucovorin calcium versus placebo (an inactive substance) for the primary prophylaxis (prevention) of cerebral toxoplasmosis in HIV-infected patients.
- Trial name
- NCT00000643
- Testing
- Pyrimethamine, Leucovorin calcium
- Where
- 24 sites in United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Toxoplasmosis, Cerebral, HIV Infections
A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS
To evaluate the effectiveness and toxicity of oral azithromycin and pyrimethamine as acute therapy for toxoplasmic encephalitis in AIDS patients.
- Trial name
- NCT00000966
- Testing
- Azithromycin, Pyrimethamine, Leucovorin calcium
- Where
- 11 sites in United States
- Volunteers
- 45 people
- Sponsor
- Pfizer
Toxoplasmosis, Cerebral, HIV Infections
A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine
To evaluate the safety and tolerance of atovaquone (566C80) in AIDS patients with central nervous system (CNS) toxoplasmosis. To evaluate the efficacy of 566C80 in the acute treatment and suppression of CNS toxoplasmosis in AIDS…
- Trial name
- NCT00001994
- Testing
- Atovaquone
- Where
- 22 sites in United States, Canada
- Sponsor
- Glaxo Wellcome
Toxoplasmosis, Cerebral, HIV Infections
Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis
To evaluate the efficacy, safety, and tolerance of atovaquone with either pyrimethamine or sulfadiazine in AIDS patients with toxoplasmic encephalitis.
- Trial name
- NCT00000794
- Testing
- Sulfadiazine, Clarithromycin, Atovaquone
- Where
- 16 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)