Clinical trials: Cervical Lesion
Cervical Precancerous Lesions, Cervical Cancer
TS Triage of HR-HPV Positive Population and Its Accuracy Study
A prospective study assessing TS accuracy in HR-HPV+ women, influencing factors, and 1-year follow-up of false-positives versus biopsy.
- Trial name
- NCT07777094
- Testing
- Colposcopy and cervical biopsy, Follow-up of TS false-positive patients
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cervical Intraepithelial Neoplasia, Papillomavirus Infections
Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL)
High-grade squamous intraepithelial lesions (HSIL), encompassing cervical intraepithelial neoplasia grade 2 (CIN2) with p16 positivity and grade 3 (CIN3), are precancerous conditions that require effective intervention.
- Trial name
- Aurora (NCT07669363)
- Testing
- Loop Electrosurgical Excision Procedure (LEEP) or Cold Knife Conization (CKC), HAL 5% with illumination
- Where
- 28 sites in China
- Volunteers
- 230 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion
- Trial name
- NNP-UE+T (NCT02329652)
- Testing
- Networked Neuroprosthetic System for Grasp and Trunk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anne Bryden
Cervical Intraepithelial Neoplasia, HPV Infection
Effect of HPV Integration on Prognosis of Young Women With CIN2 in China
Clinically, cervical precancerous lesion is one of the important diseases that endanger the life safety and fertility of young women.
- Conditions
- Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions
- Trial name
- NCT05282095
- Testing
- Follow up
- Where
- 20 sites in China
- Volunteers
- 300 people
- Sponsor
- Fujian Maternity and Child Health Hospital
Neuroendocrine Neoplasm, China
Protein Molecular Characteristics and Prognosis of Cervical Neuroendocrine Tumors
The clinical diagnosis and treatment data of 300 cases of cervical neuroendocrine tumors were collected, including age, preoperative biopsy pathology results, postoperative histopathological results, TCT results, and colposcopy…
- Conditions
- Neuroendocrine Neoplasm, China, Women, Cervical Cancer
- Trial name
- NCT06276309
- Where
- 9 sites in China
- Volunteers
- 300 people
- Sponsor
- Fujian Maternity and Child Health Hospital
Cervical Cancer, Cervical Precancerous Lesions
Trial of Two Versus Three Doses of Human Papillomavirus (HPV) Vaccine in India
The primary study hypothesis wasthat a two-dose human papillomavirus (HPV) vaccine regimen would offer similar immunogenicity and protection as that of a three-dose regimen to girls against persistent HPV infection and cervical…
- Trial name
- NCT00923702
- Testing
- Prophylactic quadrivalent HPV vaccine Merck (Gardasil®)
- Where
- 8 sites in India
- Volunteers
- 22,729 people, healthy volunteers welcome
- Sponsor
- Partha Basu
Cervical Cancers, Vulvar Cancer
A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002)
This study will evaluate the immunogenicity and tolerability of V503 (a multivalent human papillomavirus [HPV] L1 virus-like particle [VLP] vaccine) in preadolescent and adolescent participants between 9 and 15 years old and…
- Conditions
- Cervical Cancers, Vulvar Cancer, Vaginal Cancer, Genital Lesions
- Trial name
- NCT00943722
- Testing
- V503
- Volunteers
- 3,074 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Non-carious Cervical Lesion
Prevalence of Non-Carious Cervical Lesions in Patient With Gingival Recession and Associated Risk Factors
The study aims at determining the prevalence of non carious cervical lesions in patients with gingival recession in Egyptian population and associated risk factors including gingival biotype, keratinized tissue width, gingival…
- Trial name
- NCT05170529
- Where
- Egypt
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Cairo University
Squamous Intraepithelial Lesions, Laser Burn
Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous Lesions
Using multiple targeting CO2 laser ablation to treat the precancerous lesion of the female lower anogenital tracts and analyzing the data collected in the study, we aim to form the standard strategy of laser ablation method to…
- Trial name
- NCT05170620
- Testing
- laser ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Cervical Intraepithelial Neoplasia, Squamous Intraepithelial Lesions of the Cervix
Conservative Management of HSIL in Patients With Future Pregnancy Aspiration
Conservative management of high-grade squamous intraepithelial lesions (HSILs) seems safe and justified in young women (<30 years), but evidence is insufficient on whether it is also advisable for older women.
- Conditions
- Cervical Intraepithelial Neoplasia, Squamous Intraepithelial Lesions of the Cervix, Uterine Cervical Dysplasia
- Trial name
- NCT04783805
- Testing
- Conservative management with regular follow-up, Conization
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Non-carious Cervical Lesions, Adhesive Performance
Clinical Performance of a One-step Self-etch Adhesive in Non-carious Cervical Lesions at 2 Years
Objectives: One-step self-etch adhesives are the latest adhesives introduced into the market. The aim of this randomized controlled clinical trial was to test the hypothesis that a one-step self-etch adhesive performs equally…
- Trial name
- NCT04565938
- Testing
- Application of adhesive for the restoration of dental lesions with resin composite
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- University of Athens
Cervical Lesion
Risk Predictors of Extubation Failure for Cervico-medullary Junction Surgery
CVJ anomalies affecting skeleton might lead to the pressure on the neuraxis, and disturbance of the cerebrospinal fluid circulation and blood supply.
- Trial name
- CVJ-RISK (NCT03291119)
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh