Clinical trials: Cesarean
Cesarean Delivery Affecting Fetus or Newborn
Routine Maternal Leg Movements During the Second Stage and the Rate of Operative Deliveries
Cesarean delivery rates have risen in the US in a dramatic fashion from less than 5% in the 1960 to 32.7% by 2013 with stable rate around 32-33% in the last five years , cesarean delivery is associated with increased maternal…
- Trial name
- NCT03510130
- Testing
- Routine leg movement
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Paralytic Ileus
The Effects of Gum Chewing on Bowel Function Recovery Following Cesarean Section
Following all abdominal surgery, paralytic ileus commonly develops. Surgeons have traditionally withheld postoperative oral intake until the return of bowel function to prevent related complications.
- Trial name
- GUM01 (NCT01131416)
- Testing
- Gum chewing
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Vaginal Birth After Cesarean
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Trial name
- NCT00294411
- Testing
- elective cesarean section
- Sponsor
- Chinese University of Hong Kong
Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage
HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency
The objective of the Expanded Access Program is to provide HEMOLEVEN, a replacement coagulation factor XI, to patients with severe inherited factor XI deficiency where, in the opinion of the treating physician, the benefits of…
- Conditions
- Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage, Surgery
- Trial name
- EAP (NCT01701947)
- Testing
- Hemoleven
- Where
- United States
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Surgical Site Infection in Obese Women Undergoing C-section
Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery
The purpose of this study is to evaluate if preoperative antibiotics, followed by 48 hour course of broad spectrum antibiotics prevents wound infection complications in patients that are obese who undergo cesarean section.
- Trial name
- SSI (NCT01194115)
- Testing
- cephalexin & metronidazole
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- University of Cincinnati
Complications; Cesarean Section
Oxytocin to Decrease Blood Loss During Cesarean Section
The goal of this study is to determine the best dose of a drug called oxytocin, that is usually used to stop bleeding during a delivery, when used during a cesarean delivery.
- Trial name
- NCT00891150
- Testing
- Oxytocin
- Where
- Lebanon
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Opioid Use Disorder
Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking Buprenorphine
This is a single center, double-blind, randomized trial to compare the effects of intrathecal hydromorphone versus intrathecal morphine to treat post cesarean pain in patients with OUD taking buprenorphine.
- Trial name
- NCT06784180
- Testing
- Morphine, Bupivacaine, Fentanyl
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Respiratory Complications
Respiratory Morbidity Among Children Who Were Born by Elective Cesarean Section After 37-38 Weeks vs. 39 Weeks and More
Background: It is known that after Cesarean section is correlated with respiratory complication more, if done after 37-38 week of gestation than if done after 39 weeks or more.
- Trial name
- NCT02060994
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 123 people
- Sponsor
- Hillel Yaffe Medical Center
Multiple Gestation, Cesarean Delivery
Incidence of Complications Associated With Anesthesia in Multiple Gestation Undergoing Cesarean Delivery
Incidence of anesthesia related complications in multiple gestation patients undergoing cesarean delivery has not been reported in Thailand.
- Conditions
- Multiple Gestation, Cesarean Delivery, Anesthesia
- Trial name
- NCT02846129
- Where
- Thailand
- Volunteers
- 1,057 people
- Sponsor
- Mahidol University
Cesarean Section
Transcutaneous Electrical Acupoint Stimulation on Gastrointestinal Function After Cesarean Section
To determine whether treating by transcutaneous electrical acupoint stimulation (TEAS) during perioperative could alleviate the postoperative gastrointestinal complications after cesarean section under combined spinal epidural…
- Trial name
- TEAS (NCT02416310)
- Testing
- TEAS
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Cesarean Birth, Massage
Effects of Rehabilitation on Cesarean Scar Symptoms and Physical Recovery
Cesarean section is the most common inpatient surgical procedure worldwide, with rates continuing to rise; in Canada, approximately one in three births occur by cesarean.
- Conditions
- Cesarean Birth, Massage, Rehabilitation, Exercise
- Trial name
- NCT07897253
- Testing
- Direct scar massage, Indirect massage group
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Concordia University, Montreal
Failure of Cervical Dilatation, Complications; Cesarean Section
Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial
The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity
- Conditions
- Failure of Cervical Dilatation, Complications; Cesarean Section, Wound Infection,, External Causes of Morbidity and Mortality
- Trial name
- NCT01954719
- Testing
- cervix dilated after surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Cesarean Delivery Procedures
Randomized Controlled Trial of Bladder Flap vs.None
Objective: To compare outcomes in cesarean section patients undergoing bladder flap versus none. Hypotheses: Operative time will be reduced with the elimination of a bladder flap during cesarean delivery and intra-operative and…
- Trial name
- NCT00470288
- Testing
- bladder flap during cesarean section
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mountain Area Health Organization Center
Surgical Wound Infection
Supplemental Perioperative Oxygen to Reduce the Incidence of Post-cesarean Wound Infection
The purpose of this study is to determine if the use of supplemental oxygen at 80% FIO2 can reduce the incidence of surgical site infection after emergency cesarean section.
- Trial name
- NCT01340534
- Testing
- Supplemental oxygen 80% FIO2, Use of air (no oxygen during surgery)
- Where
- Panama
- Volunteers
- 370 people
- Sponsor
- Saint Thomas Hospital, Panama
Fetal Membranes, Premature Rupture
Perinatal Outcome After Premature Rupture of Membranes
Premature rupture of membranes is an important cause of neonatal morbidity and mortality, mainly because of the complications associated with this pathology (oligohydramnios, cord compression or prolapse, infection).
- Trial name
- NCT01538030
- Where
- Panama
- Volunteers
- 80 people
- Sponsor
- Saint Thomas Hospital, Panama
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Research Objective: Primary outcome -To compare efficacy Intrauterine vs Sublingual MISOPROSTOL in addition to Oxytocin in reducing blood loss of post-cesarean section in high risk women Secondary outcome -To study…
- Trial name
- NCT04560218
- Testing
- sublingual Misoprostol, Intrauterine Misoprostol
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Breast Feeding, Caesarean Section;Stillbirth
Skin-to-Skin Contact With a Sling in Primipar Mothers Who Delivered by Cesarean Section
The first hours after birth are critical for the physiological and psychological adaptation process of the newborn from intrauterine to extrauterine life.
- Trial name
- NCT06502860
- Testing
- skin to skin with sling
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Cesarean Section Complications, Uterine Bleeding
Surgical Incision Closure Method to Prevent Niche Formation After Cesarean Section- Randomized Controlled Trial
In the last decade we have been exposed to the complication of a caesarean section called a "niche". A niche is an anaerobic defect in the location of the cesarean section, which represents the discontinuity of the endometrium…
- Trial name
- NCT04766073
- Testing
- Niche prevention suture
- Where
- Israel
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Induction of Labor
Induction of Labor With a Foley Balloon Catheter: Inflation With 30ml Compared to 60ml
The rate of labor induction is rising throughout the United States for a variety of reasons. Medical conditions that lead to increased risk of prolonging the pregnancy to both mother and fetus are not infrequent.
- Trial name
- NCT00451308
- Testing
- Induction of labor with foley balloon - 60cc of saline, Induction of labor with foley balloon with 30cc
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of California, San Francisco