Clinical trials: Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Preliminary Effectiveness and Feasibility of Transcutaneous Acupoints Electrical Stimulation on Chemotherapy-induced Peripheral Neuropathy Among Children With Acute Lymphoblastic Leukemia
The first goal of this clinical trial is to assess the feasibility of transcutaneous acupoints electrical stimulation (TAES) on children with acute lymphoblastic leukemia (ALL).
- Trial name
- NCT07319481
- Testing
- Transcutaneous Acupoints Electrical Stimulation (TAES)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Chemotherapy-induced Peripheral Neuropathy
Diagnostic of Chemotherapy Induced Neuropathy in Children
The purpose of this study is to determine the diagnostic accuracy of a newly developed tool (Electrochemical Skin Conductances (ESC) measurement) easy-to-perform, non-invasive, highly reproductible and not requiring specific…
- Trial name
- SUDOPED (NCT04262778)
- Testing
- electrochemical skin conductance measurement
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer
Efficacy of Cryotherapy in Managing Chemotherapy-Induced Peripheral Neuropathy in Children With Leukemia
This study aimed to assess the efficacy of cryotherapy in controlling Peripheral Neuropathy in cancer children
- Trial name
- NCT06543264
- Testing
- Cryotherapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Cancer, Neuropathy
Nutritional Supplement for Treating Chemotherapy Induced Neuropathy
Administration of a nutritional supplement containing palmitoyethanolamide, alpha lipoic acid, vitamin B12, vitamin B6 , vitamin B1, nicotinamide, magnesium, zinc, vitamin E, and superoxide of dismutase in individuals receiving…
- Conditions
- Cancer, Neuropathy, Chemotherapy Induced Pain Neuropathy, Chemotherapy-Induced Peripheral Neuropathy
- Trial name
- NCT07022938
- Testing
- Epineuron
- Where
- Greece
- Volunteers
- 71 people
- Sponsor
- Aristotle University Of Thessaloniki
Breast Cancer
"Electro Acupuncture in the Treatment and Management of Chemotherapy Induced Peripheral Neuropathy"
To evaluate the effectiveness of Electro acupuncture (EA) for treatment of persistent painful CIPN symptoms in patients with stages 1-3 breast cancer treated with docetaxel chemotherapy 6 months prior
- Trial name
- NCT02821442
- Testing
- Acupuncture
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Chemotherapy-induced Peripheral Neuropathy
The Effectiveness and Cost-effectiveness of Acupuncture in Managing Chemotherapy-induced Peripheral Neuropathy
The purpose of this study is to determine whether a course of acupuncture is effective in the management of peripheral neuropathy related pain in patients receiving chemotherapy.
- Trial name
- NCT02553863
- Testing
- Acupuncture, Standard care
- Where
- 2 sites in Hong Kong
- Volunteers
- 87 people
- Sponsor
- The Hong Kong Polytechnic University
Distorted; Balance, Motor Deficit
Virtual Reality-Based Exercise in Cancer Patients
The aim of the present study is to evaluate an innovative virtual reality-based balance training intervention for improving clinically relevant motor performances (balance and gait) in cancer patients.
- Trial name
- NCT02165163
- Testing
- Balance Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Chemotherapy Induced Neuropathic Pain, Neuropathy Toxic
Prospective Exploratory Study of a Multiomic Blood Biomarker Panel to Predict Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The goal of this prospective, multicenter, observational cohort study with longitudinal blood sampling and standardized neurological evaluation over 6 months is to identify biomarkers to predict the overall occurrence of chronic…
- Conditions
- Chemotherapy Induced Neuropathic Pain, Neuropathy Toxic, Taxane-induced Peripheral Neuropathy, Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Trial name
- PRECISE1 (NCT07511569)
- Testing
- longitudinal blood sampling and standardized neurological evaluation over 6 months
- Volunteers
- 192 people
- Sponsor
- Centre Hospitalier de Bligny
Chemotherapy-induced Peripheral Neuropathy
Physiologic Measure of VIPN
The purpose of this study is the development of a physiologic endpoint using a novel technology that would provide an objective, easy to use and more sensitive assessment of VIPN in children and adolescents.
- Trial name
- NCT04786977
- Testing
- No Intervention, Observational Study
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Pediatric Cancer, Pediatric Brain Tumor
Playful Sensorimotor Training in Pediatric Brain Tumor Patients
Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and clinically relevant side-effect of cancer treatment.
- Conditions
- Pediatric Cancer, Pediatric Brain Tumor, Chemotherapy-induced Peripheral Neuropathy, Sensorimotor Polyneuropathy
- Trial name
- RESET (NCT03334162)
- Testing
- Sensorimotor training
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Basel
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions
The goal of this clinical trial is to compare the effectiveness of Transcutaneous Acupoints Electrical Stimulation (TAES) and Auricular Acupressure (AA) on subject CIPN symptoms, sensory function, motor and physical function…
- Trial name
- NCT07279818
- Testing
- Transcutaneous Acupoints Electrical Stimulation (TAES), Auricular Acupressure (AA), No intervention
- Where
- China
- Volunteers
- 132 people
- Sponsor
- The Hong Kong Polytechnic University
Chemotherapy-induced Peripheral Neuropathy, Pediatric Cancer
Preventing Sensory and Motor Dysfunctions in Children Receiving Neurotoxic Chemotherapy
The investigators would like to conduct a prospective, multicenter, two-armed trial (RCT with follow-up). Patients will be recruited from 7 centers (CH/D).
- Trial name
- PrepAIR (NCT05606588)
- Testing
- Playful sensorimotor training
- Where
- 2 sites in Switzerland
- Volunteers
- 131 people
- Sponsor
- University of Basel
Peripheral Sensory Neuropathy
Clinical Study on Acetyl-L-Carnitine
Chemotherapy-induced peripheral neuropathy (CIPN) is a common clinical dose-limiting adverse drug reaction, and the primary manifestations are different degree of neuromotor, sensorineural and autonomic nervous dysfunction.
- Trial name
- NCT01526564
- Testing
- Acetylcarnitine
- Volunteers
- 239 people
- Sponsor
- Lee's Pharmaceutical Limited
Leukemia, Children With Cancer
Technology-Assisted Yoga and Exercise on Neuropathy and Pain in Children With Leukemia
The study was planned to examine the effects of technology-supported yoga and exercise on chemotherapy-induced peripheral neuropathy and pain in children aged 5-18 years with leukemia.
- Conditions
- Leukemia, Children With Cancer, Yoga Therapy, Excercise
- Trial name
- yogaCIPN (NCT06512012)
- Testing
- yoga and exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Dokuz Eylul University
Testicular Germ Cell Tumor
Study of Cisplatin-Induced Peripheral Neuropathy in Patients With Germ Cell Tumor
This is a prospective observational study investigating the incidence, characteristics of, and change in chronic neuropathy symptoms related to cisplatin using the EORTC CIPN-20 instrument.
- Trial name
- NCT02677727
- Testing
- EORTC QLQ-CIPN20
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Costantine Albany
Acute Lymphoblastic Leukemia ALL
Tracjectories and Predictors of Chemotherapy Induced Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia
The goal of this study is to explore the trajectory patterns of chemotherapy induced peripheral neuropathy over the course of chemotherapy and identify predictors of distinct trajectories in children with acute lymphoblastic…
- Trial name
- NCT07326930
- Where
- 3 sites in China
- Volunteers
- 173 people
- Sponsor
- The Hong Kong Polytechnic University
Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy
This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.
- Conditions
- Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma
- Trial name
- IOPN (NCT03655587)
- Testing
- Solid ankle foot orthotic, Resting night splint
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Cancer, Childhood Cancer
Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors
The purpose of this study is to determine feasibility and acceptability of a six-week at-home light therapy protocol in childhood cancer survivors, to identify facilitators and barriers to implementing this intervention, and to…
- Conditions
- Cancer, Childhood Cancer, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- NCT07019259
- Testing
- Anodyne Therapy System
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Peripheral Neuropathy
Effect of Shock Wave In Reducing Chemotherapy- Induced Peripheral Neuropathy In Adult and Pediatric Tumors Patients
This study aimed to assess the efficacy of shock wave in reducing Chemotherapy- Induced Peripheral Neuropathy in adult and pediatric tumors patients.
- Trial name
- NCT05111730
- Testing
- The Shock wave Therapy.
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- South Valley University
Gynecologic Cancer, Chemotherapy-induced Peripheral Neuropathy
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer
The aim of this study is to evaluate the effect of cryocompression therapy on the incidence and degree of taxane-induced peripheral neuropathy in gynecologic cancer patients receiving chemotherapy.
- Trial name
- NCT04563130
- Testing
- Cryocompression
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Duke University