Clinical trials: Chest Wall Disorders
Pectus Excavatum
Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum
This study is a Phase 3, multicenter, non-randomized study to evaluate the safety and efficacy of the next-generation outpatient Magnetic Mini-Mover Procedure (3MP) in 15 patients aged 8-14 years for the correction of pectus…
- Trial name
- 3MP (NCT01327274)
- Testing
- Magnetic Mini-Mover Procedure (Magnimplant)
- Where
- 3 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Harrison
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Critically Ill, Acute Lung Injury
Respiratory Mechanics and Pleural Effusion
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.
- Conditions
- Critically Ill, Acute Lung Injury, ARDS
- Trial name
- NCT00258518
- Testing
- mechanical ventilation/CT Scan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Policlinico Hospital
Chest Wall Deformity, Funnel Chest
Chest Wall Deformities in Children - Epidemiological Data
Pectus excavatum (PE) or funnel breast is the most common congenital deformity of the chest wall, which occurs in about 1 in 400 births with a boy to girl ratio of 4: 1 to 3: 1.
- Trial name
- NCT04448574
- Testing
- Chest Wall Deformities Questionaire
- Where
- 2 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ascending Aortic Aneurysm
Biomechanical Properties of the Human Ascending Aortic Wall in Aneurysm
The aim of the study is to analyze the efficacy of the surgical tretment in patients with ascending aortic aneurysm and dilatation.
- Trial name
- NCT05839990
- Testing
- Surgery
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Chest Wall and Spinal Disorders
The Pediatric Spine Foundation
The Pediatric Spine Foundation is a registry designed to assist spine surgeons to efficiently identify and track patients with chest wall and spinal disorders.
- Trial name
- NCT02540915
- Testing
- Standard of Care - Registry
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Colorado, Denver
Bone Diseases, Obesity
Stereophotogrammetry of the Torso in Healthy Individuals and Patients With Scoliosis, Chest Wall Deformations, or Obesity
Background: Stereophotogrammetry (SP) uses four sets of digital cameras to generate a three-dimensional computer image. Unlike other types of evaluations which require radiation, SP only uses computer images to learn more about…
- Conditions
- Bone Diseases, Obesity, Healthy Volunteers
- Trial name
- NCT01352949
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Preterm Infant
Effect of Kinesiotaping Application in Preterm Infants Undergoing Noninvasive Ventilation
Kinesiotaping (KT) applied to the thorax is believed to enhance breathing by supporting the respiratory muscles. Infants born premature usually have respiratory problems because of depletion of surfactant and respiratory muscle…
- Trial name
- NCT03660358
- Testing
- kinesiotape application
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Baskent University
Preterm, Premature
Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants
This study aimed to evaluate the effects of kinesio taping on blood gas parameters, respiratory rate, heart rate, oxygen saturation, and pressure limits in preterm infants with RDS who are on NIV.
- Conditions
- Preterm, Premature, Infant, Newborn, Diseases, Respiratory Distress Syndrome
- Trial name
- NCT06285669
- Testing
- kinesiotaping application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ondokuz Mayıs University
Chest Wall Disorder
Three-dimensional Scanning of the Chest: a Comparison Between Three Different Imaging Modalities
Recently, three-dimensional scanning of the torso has been proposed as an alternative for two-view chest radiographies and computed tomography to determine the severity of pectus excavatum without exposure to ionizing radiation.
- Trial name
- NCT04279886
- Testing
- Three-dimensional scans
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pectus Excavatum
Quantifying Changes in the Thoracic Wall After Nuss Bar Removal in Pectus Excavatum Patients Using 3D Imaging
Pectus excavatum (funnel chest) is the most common congenital anterior thoracic wall deformity. It can be associated not only with cosmetic concerns but also with psychosocial and limiting somatic complaints.
- Trial name
- CHEST (NCT07498699)
- Where
- Netherlands
- Volunteers
- 69 people
- Sponsor
- Erik de Loos
Bronchial Asthma, Asthma
HFCWO in Hospitalized Asthmatic Children
To determine whether or not high frequency chest wall oscillation (in the form of the VestTM) is superior to regular asthma therapy in the management of children hospitalized with moderate to severe asthma.
- Conditions
- Bronchial Asthma, Asthma, Status Asthmaticus
- Trial name
- NCT00722020
- Testing
- VEST
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Hill-Rom
Respiration, Artificial
Effects of Sternal Wall Pressure in Children
This protocol is a prospective, pilot, observational study in the Pediatric Intensive Care Unit (PICU), Progressive Care Unit (PCU) and the Operating Room (OR) settings at the Children's Hospital of Philadelphia (CHOP).
- Trial name
- SWP (NCT00628407)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospital of Philadelphia
Abdominal Hernia, Abdominal Wall Defect
To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery
Pediatric epidural anesthesia has emerged as a safe and effective regional anesthesia technique for providing intraoperative and postoperative analgesia in thoracic and abdominal surgery.
- Conditions
- Abdominal Hernia, Abdominal Wall Defect, Abdominal Neoplasm, Urogenital Disease
- Trial name
- NCT05308771
- Testing
- VPC syringe
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Tivoli
Esophageal Atresia, Oesophageal Atresia
Evaluation of the Respiratory Impact After Conventional or Minimally Invasive Esophageal Atresia Surgery
Right thoracotomy, conventional approach to esophageal atresia repair, leads to up to 60% radiological chest wall sequelae anomalies. The impact of these anomalies on the patient's respiratory function remains unknown.
- Conditions
- Esophageal Atresia, Oesophageal Atresia, Restrictive Lung Disease, Chest Wall Anomaly
- Trial name
- RestriMIS (NCT04136795)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Funnel Chest
Evaluation of Chest Wall Motility After MIRPE
Pectus excavatum (PE) is the most common congenital deformity of the chest wall and surgical treatment using the minimally invasive technique (MIRPE) is consolidating as the choice to perform PE correction.
- Trial name
- NCT05124626
- Testing
- MIRPE with two bars, MIRPE with one bar
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
COPD
Effectiveness of Chest Wall Mobilization Program in Improving Respiratory Function for Patients With COPD
Patients with severe COPD will be recruited from the Respiratory Outpatient Clinic of Kowloon Hospital. Baseline (pre-intervention) assessment for all recruited subjects will be conducted by one physiotherapist assessor who is…
- Trial name
- NCT04122365
- Testing
- Chest Wall Mobilization Program, Control
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Scoliosis Idiopathic Adolescent, Chest Deformities
Sagittal Spine Balance in Patients With Chest Wall Deformity
Does the funnel deformity affects the sagittal balance of the spine? This question is a result of a Principal Investigator's novel observation, that in some cases restoring the correct balance reduce the distance between the…
- Trial name
- NCT07070609
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Pomeranian Medical University Szczecin
COPD (Chronic Obstructive Pulmonary Disease), Cystic Fibrosis (CF)
ELECTROVEST: Electro-Stimulation Vibratory Vest for Pulmonary Rehabilitation in Patients With Chronic Respiratory Diseases
This study will evaluate the effectiveness, safety, and tolerability of a novel wearable device, the ELECTROVEST, designed to improve airway clearance in patients with chronic respiratory diseases.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Cystic Fibrosis (CF), Bronchiectasis Adult, Asthma Bronchiale
- Trial name
- Electrovest (NCT07175012)
- Testing
- ELECTROVEST, The Vest® Model 105
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Desmoid, Desmoid Fibromatosis of Skin
Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis
In this study Drug-eluting microbeads (DEB) loaded with Doxorubicin will be delivered into the target Desmoid Fibromatoses (DF) tissue via selective arterial embolization by angiographic technique.
- Conditions
- Desmoid, Desmoid Fibromatosis of Skin, Desmoid Neoplasm of Chest Wall, Desmoid Tumor Caused by Somatic Mutation
- Trial name
- NCT03966742
- Testing
- Drug Eluting Bead Embolization (DEB) for Desmoid Fibromatosis
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Rabin Medical Center