Clinical trials: Chest--Diseases
Gastrointestinal Disease, Esophageal Cancer
PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide
The goal of this clinical research study is to use a new breathing test that measures the amount of nitric oxide (NO) you exhale.
- Conditions
- Gastrointestinal Disease, Esophageal Cancer, Lung Cancer
- Trial name
- NCT00867477
- Testing
- Breathing Test, Respiratory Symptoms Questionnaire, Pet Scan
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure
Comparison Between Internal and External Chest Impedance Measurement
To compare two methods of chest impedance: the Medtronics Optivol Measurement via CRT pacemakers for patients with heart failure and external non-invasive measurement
- Trial name
- NCT01296282
- Testing
- Medronics CRT Optivol Impedance Measurement, External Thoracic Impedance Measurement
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Chronic Obstructive Pulmonary Disease, Neuromuscular Disease
Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation
The critical nature of respiratory diseases, the continuously increasing prevalence of these conditions, and the subjective perception of patients vis-à-vis their pulmonary function and health status underscore the importance of…
- Conditions
- Chronic Obstructive Pulmonary Disease, Neuromuscular Disease, Chest Wall Disorders, Obesity Hypoventilation Syndrome
- Trial name
- TeleMotiNIV (NCT01560741)
- Testing
- Telemonitoring tools, Usual Care
- Where
- Portugal
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Joao
Ovarian Neoplasms, Non-Small-Cell Lung Carcinoma
A Phase I Clinical Study With Investigational Compound LTT462 in Adult Patients With Specific Advanced Cancers.
A phase I study of LTT462 in patients with advanced solid tumors that harbor MAPK pathway alterations.
- Conditions
- Ovarian Neoplasms, Non-Small-Cell Lung Carcinoma, Melanoma, Other Solid Tumors
- Trial name
- NCT02711345
- Testing
- LTT462
- Where
- 7 sites in United States, Germany and 4 more
- Volunteers
- 65 people
- Sponsor
- Novartis Pharmaceuticals
Lung Cancer
SGLT2 Inhibitors and Survival in Lung Cancer Patients With Diabetes
The goal of this clinical trial The goal of this clinical trial is to evaluate whether SGLT2 inhibitor drugs can extend overall survival or delay the progression of the tumor in patients with both advanced lung cancer and…
- Trial name
- NCT07272057
- Testing
- SGLT-2 inhibitor
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Brain Cancer, Lung Cancer (Diagnosis)
Head-to-Head Evaluation of the Cancer Ontology Supervised Multimodal Orchestration (COSMO) AI System Versus Pathologist-Only Review
This study evaluates the diagnostic performance of the Cancer Ontology Supervised Multimodal Orchestration (COSMO) AI system for cancer subtype classification and compares it head-to-head with pathologist-only review.
- Conditions
- Brain Cancer, Lung Cancer (Diagnosis), Renal Cancer
- Trial name
- COSMO (NCT07307157)
- Testing
- Digital Pathology Evaluation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Bronchiolitis
Chest Physiotherapy in Bronchiolitis
Randomized trial of chest physiotherapy in outpatients with bronchiolitis under two years of age, during two consecutive seasonal outbreaks.
- Trial name
- NCT04260919
- Testing
- Chest physiotherapy
- Volunteers
- 45 people
- Sponsor
- Universidade do Porto
Pain, Acute, Congenital Heart Disease
Transverse Thoracic Plane Block in the Pediatric Cardiac Patient
Postoperative pain after cardiothoracic surgery can be a significant problem interfering with recovery, yet difficult to manage due to the sedating effects of opiates.
- Trial name
- TTPPCT (NCT04138745)
- Testing
- Transverse Thoracic Plane Block
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Lung Cancer
Percutaneous Thermal Ablation in Lung Tumors
Lung cancer has a high incidence globally, with Egypt having it as the third most common and most lethal cancer, affecting 16.9% of males and 3.8% of females.
- Trial name
- Radiofrequency (NCT06891183)
- Testing
- Percutaneous thermal ablation of lung tumors
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Non-small Cell Lung Cancer, Radiation Toxicity
Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy
Lung cancer is the most common cause of cancer death in Canada. For approximately 30% of patients that present with locally-advanced non-small cell lung cancer (NSCLC), the standard treatment is curative-intent concurrent…
- Trial name
- RICT-LUNG (NCT03416972)
- Testing
- Standard platinum-based chemoradiotherapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Cancer, Abdominal Cancer
Respiratory Tumor and Normal Tissue Motion
Primary Objectives: To collect accurate and reliable respiration-induced anatomic structure motion data using four-dimensional (4-D) imaging technology.
- Trial name
- NCT00415675
- Testing
- Motion CT Scans
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- M.D. Anderson Cancer Center
Congenital Diaphragmatic Hernia
Measurement of Lung Area at Chest Radiography to Define the Prognosis in Newborns With CDH
CDH represents a malformative disorder characterized by an incomplete diaphragm formation. This results in poor lung development (pulmonary hypoplasia), associated with altered vascularization of the lung (pulmonary…
- Trial name
- NeoAPACHE (NCT04396028)
- Testing
- data collection
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Lung Cancer, Ventricular Failure, Right
Right Side of Heart Function After Lung Surgery
The purpose of this study is explore the impact of lung cancer surgery on the function of the right side of the heart.
- Trial name
- NCT01892800
- Testing
- Lung resection
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University of Glasgow
Lung Cancer
Evidence-Based Nursing for Fatigue and Quality of Life in Lung Cancer Chemotherapy
This prospective randomized controlled trial investigated the effects of an evidence-based nursing intervention under a quantitative assessment strategy (EB-NQAS), utilizing the Edmonton Symptom Assessment Scale (ESAS), on…
- Trial name
- NCT07049237
- Testing
- Evidence-Based Nursing Under Quantitative Assessment Strategy (EB-NQAS), Routine Nursing Care
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First Hospital of Hebei Medical University
Thymoma, Stomach Neoplasms
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Background: Malignant mesothelioma is a malignancy arising from the mesothelial cells of the pleura, peritoneum, pericardium, or tunica vaginalis. Mesothelioma accounts for 0.10% of deaths annually in the United States.
- Conditions
- Thymoma, Stomach Neoplasms, Pancreatic Neoplasms, Mesothelioma
- Trial name
- NCT01950572
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Institute (NCI)
Carcinoma, Non-Small -Cell Lung
Analysis of Brain Metastasis in Patients With Lung Cancer
This study will examine patients with non-small cell lung cancer metastasis, that is, the distant spreading of tumors to the brain, and compare them with patients without brain metastasis.
- Trial name
- NCT00071344
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Non Small Cell Lung Cancer
Tipifarnib in Advanced Squamous NSCLC With Oncogen HRAS MutAtionS
This Phase II study consists of 2 parts: 1) pre-screening phase and 2) treatment phase. The pre-screening phase will investigate the presence of HRAS mutations in subjects with a histologically or cytologically confirmed…
- Trial name
- NCT03496766
- Testing
- Tipifarnib
- Where
- 30 sites in Spain
- Volunteers
- 9 people
- Sponsor
- Spanish Lung Cancer Group
Core Stabilization, Respiration
Core Stabilization Training on Chest Expansion, Functional Capacity, Trunk Muscle Endurance in Hearing-Impaired Children
Children's motor skills and physical performance increase with age due to the development of neuromuscular and cardiorespiratory systems.
- Conditions
- Core Stabilization, Respiration, Functional Capacity, Endurance
- Trial name
- NCT06354400
- Testing
- Core stabilization training
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
Pectus Excavatum, Pectus Carinatum
Impact of Surgical Treatments of Thoracic Deformation on Cardiopulmonary Functions
Pectus excavatum or carinatum are the most common congenital deformations of the ventral thoracic wall. Several different surgical methods with different techniques to correct these deformations have been described.
- Trial name
- NCT02163265
- Testing
- Surgery
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Medical University Innsbruck
Melanoma, Meningioma
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Background: The National Cancer Institute (NCI) Surgery Branch has developed an experimental therapy for treating patients with cancer that involves taking white blood cells from the patient, growing them in the laboratory in…
- Conditions
- Melanoma, Meningioma, Breast Cancer, Non-Small Cell Lung Cancer
- Trial name
- NCT01967823
- Testing
- Anti-NY ESO-1 mTCR PBL, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Cancer Institute (NCI)
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