Clinical trials: Child Allergy
Acute Bronchial Obstruction, Asthma
Efficacy of Formoterol vs Ipatropioum Bromide Plus Fenoterol in Children (5-<12 Years) With Acute Bronchial Obstruction
To determine efficacy and tolerability of inhaled Formoterol vs nebulized Ipatropioum Bromide plus Fenoterol in cumulative sequential doses in asthmatic children (5-<12 years) with acute bronchial obstruction attending emergency…
- Trial name
- NCT00460577
- Testing
- Formoterol fumerate, fenoterol/ipratropium bromide
- Where
- 2 sites in Venezuela
- Volunteers
- 60 people
- Sponsor
- Novartis
Food Allergy
Improving the Safety of Oral Immunotherapy for Cow's Milk Allergy
Allergy to cow's milk is the most common food allergy affecting children. There is currently no accepted routine clinical therapy to cure milk allergy.
- Trial name
- SOCMA (NCT02216175)
- Testing
- SLIT to cow's milk, Low dose OIT, Conventional OIT to cow's milk
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 68 people
- Sponsor
- Imperial College London
Asthma
Validation of the Hospital Asthma Severity Score (HASS)
The purpose of this research will be to evaluate the reliability and validity of the HASS tool in a cohort of patients' ages 7 to18 years old against the gold standard of spirometry, and in ages 2 to 6 against spirometry, if…
- Trial name
- HASS (NCT02782065)
- Testing
- Not an interventional study
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Boston Children's Hospital
Asthma, Cockroach Hypersensitivity
Cockroach Nasal Allergen Challenge Pilot
This research is being done to look at the body's response to cockroach extract, an allergen, when sprayed into the nose. The spraying of the cockroach extract into the participant's nose is called Nasal Allergen Challenge (NAC).
- Trial name
- NCT02710136
- Testing
- Glycerinated German Cockroach Allergenic Extract
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Study of MAP0010 in Asthmatic Children and Adolescents
The objectives of this study are to evaluate the efficacy, tolerability and pharmacokinetics of 2 doses of MAP0010 (Unit Dose Budesonide) in asthmatic children/adolescents.
- Trial name
- NCT00697801
- Testing
- MAP0010 low dose, MAP0010 high dose
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Allergan
Cow's Milk Protein Allergy
Tolerance and Growth Outcomes in Children Diagnosed With Cow's Milk Protein Allergy and Prescribed an Extensively Hydrolyzed Casein Formula (Damira 2000©) in Spain
Damira 2000© is a 100% extensive casein hydrolysate (eHCF). It is formulated to help reverse growth retardation as a result of cow's milk proteins allergy (CMPA), to be well tolerated and to help improve symptoms.Damira 2000 is…
- Trial name
- DELISA (NCT06273371)
- Testing
- Damira 2000 Infant formula
- Where
- 8 sites in Spain
- Volunteers
- 61 people
- Sponsor
- Lactalis
Asthma
A Dose-ranging Study of Fluticasone Furoate (FF)
This is a Phase IIb, multi-centre, stratified, randomised, double-blind, double-dummy, parallel-group, placebo and active controlled study in children aged 5-11 years with persistent uncontrolled asthma.
- Trial name
- NCT01563029
- Testing
- Fluticasone Furoate, Fluticasone Propionate
- Where
- 139 sites in United States, Bulgaria and 13 more
- Volunteers
- 597 people
- Sponsor
- GlaxoSmithKline
Asthma in Children
Symptom Clusters in Children With Exacerbation-prone Asthma
Pediatric participants with exacerbation-prone asthma will receive an intramuscular injection of triamcinolone acetonide and will be followed for 48 weeks.
- Trial name
- NCT04002362
- Testing
- Triamcinolone Acetonide
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emory University
Dermatitis, Contact, Dermatitis
Post-Marketing Clinical Follow-Up Trial to Evaluate the Performance and Safety of the Medical Device 047 TD Dermatitis Cream in Adults and Children With Atopic and Contact Dermatitis Symptoms Confirmed by Clinical Parameters
The study aims to evaluate and confirm the performance of 047 TD Dermatitis cream in the improvement of eczematous dermatitis and contact dermatitis, throughout a reduction in disease severity and symptoms.
- Conditions
- Dermatitis, Contact, Dermatitis, Dermatitis, Chronic, Dermatitis, Eczematous
- Trial name
- NCT07056569
- Testing
- 047_TD Dermatitis cream twice a day for 28 days
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Biokosmes Srl
Diabetes Mellitus, Type 1, Epilepsy
Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context
Parents of children with long-term health conditions (LTCs) can experience shame related to parenting. Whilst self-compassion interventions (SCIs) can reduce parental shame, this has not been studied with parents of children with…
- Conditions
- Diabetes Mellitus, Type 1, Epilepsy, Asthma, Shame
- Trial name
- NCT03504605
- Testing
- Online self-compassion intervention
- Where
- United Kingdom
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Asthma in Children, Allergy
Childhood Allergy and the Neonatal Environment
The purpose of this research study is to study the relationship between childhood asthma, allergies, and early-life environmental factors that may cause childhood asthma and allergies.
- Trial name
- CANOE (NCT04215783)
- Where
- 4 sites in United States
- Volunteers
- 499 people
- Sponsor
- University of Wisconsin, Madison
Dermatitis, Atopic
Histamine Pharmacogenetics in Children With Atopic Dermatitis
The primary goal of the study is to investigate the impact of a common genetic polymorphism in a histamine detoxification enzyme that may well have a common role in regulating the expression of atopic dermatitis (AD) and other…
- Trial name
- NCT00277433
- Testing
- Buccal Swab
- Where
- 7 sites in United States
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Atopic Dermatitis
Correlation Study Between PEST and SCORAD in Management of Atopic Dermatitis With Ceradan® Regimen
This is a prospective, open label, single arm, and observational and multicenter study to assess the correlation between PEST and SCORAD scores in the management of AD with the Ceradan® regimen.
- Trial name
- COPES (NCT02073591)
- Testing
- Ceradan Cream, Ceradan Wash
- Where
- 2 sites in Singapore
- Volunteers
- 58 people
- Sponsor
- Hyphens Pharma Pte Ltd
Celiac Disease, Malabsorption Syndromes
Immune Responses to Gluten
This is a study of immune responses after eating gluten powder in people with celiac disease and healthy controls.
- Conditions
- Celiac Disease, Malabsorption Syndromes, Digestive System Disease, Intestinal Disease
- Trial name
- NCT05209568
- Testing
- Gluten Powder
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Asthma in Children
Improving Asthma Referrals Following Emergency Department Evaluation
Asthma is the most common chronic condition among children and many children seek emergency department (ED) care. A key aspect of ED asthma management at the time of discharge is appropriate outpatient referral.
- Trial name
- NCT05072808
- Testing
- View PACCI-ED and referral recommendations
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Wayne State University
Peanut Allergy
Oral Desensitization to Peanut in Peanut-Allergic Children and Adults Using Characterized Peanut Allergen OIT
This is a multi-center, randomized, double-blind placebo controlled study of efficacy and safety of characterized peanut oral immunotherapy in peanut allergic individuals.
- Trial name
- ARC001 (NCT01987817)
- Testing
- AR101 powder provided in capsules
- Where
- 8 sites in United States
- Volunteers
- 56 people
- Sponsor
- Aimmune Therapeutics, Inc.
Internet Gaming Disorder, Internet Addiction
Neurotrophic Factors, Impulsivity, and Reward Sensitivity in Children With Internet Gaming Disorder
Research and knowledge regarding the neurobiology of behavioral addictions and Internet Gaming Disorder (IGD) remain limited compared to substance and alcohol use disorders.
- Trial name
- NCT07590180
- Testing
- Clinical Evaluation and Biochemical Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events
Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia
This randomized controlled study is to evaluate the effectiveness of inhaling penehyclidine hydrochloride in reducing perioperative respiratory adverse events in children at risk undergoing minor elective surgery.
- Conditions
- Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events, Anticholinergics, Inhalation Therapy; Complications
- Trial name
- PEPSI (NCT06624696)
- Testing
- Penehyclidine hydrochloride, Normal Saline
- Where
- 2 sites in China
- Volunteers
- 204 people
- Sponsor
- Sun Yat-sen University
Atopic Dermatitis / Eczema
To Evaluate the in Use Tolerance of E45 Eczema Repair Emollient in Babies and Children With (Very(Dry/Atopic Skin
The investigation will evaluate, under dermatological control, the cutaneous in-use tolerance of E45 Eczema Repair Emollient with two or three times daily application, over a period of two weeks on children and babies with…
- Trial name
- NCT02857062
- Testing
- E45 Eczema Repair Emollient
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
T Cell Response to Asthma in HIV-infected Patients Before and After Starting Treatment
Children With HIV and Asthma (CHIVAS)
To explore allergen-specific effector and regulatory T cell response in HIV-infected children before and after HAART initiation
- Trial name
- NCT01644370
- Testing
- HAART
- Where
- 2 sites in Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
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