Clinical trials: Child Development Disorder
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Neurofeedback, Autistic Disorder
Neurofeedback Intervention in Children With Autism Spectrum Disorder (ASD)
This project aims to: explore the effectiveness of Neurofeedback therapy for children diagnosed with Autism Spectrum Disorder (ASD) assess if cognitive functions are affected before and after Neurofeedback Intervention
- Conditions
- Neurofeedback, Autistic Disorder, Autism Spectrum Disorder, Neurodevelopmental Disorders
- Trial name
- NCT05254769
- Testing
- Neurofeedback Equipment (Cygnet) by BEE Medic GmbH Technologies, Baden-Wurttemberg, Germany.
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Child Development, Parenting
The Sugira Muryango PLAY Collaborative
The Research Program on Children and Adversity (RPCA) has successfully grown its evidence-based home-visiting program-Sugira Muryango (SM)-in Rwanda, as policies and programs aligned with the Rwandan social protection system have…
- Conditions
- Child Development, Parenting, Parent-Child Relations, Child Malnutrition
- Trial name
- NCT04257383
- Testing
- Sugira Muryango
- Where
- Rwanda
- Volunteers
- 1,333 people, healthy volunteers welcome
- Sponsor
- Boston College
Autistic Spectrum Disorders
TSO in Pediatric Autistic Spectrum Disorders
The primary objective of this study is to evaluate and compare the safety and efficacy of Trichuris suis ova (TSO) therapy (versus placebo) in pediatric patients with autism.
- Trial name
- TSO (NCT01734941)
- Testing
- TSO
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Hadassah Medical Organization
Hirschsprung's Disease (HD)
Neuropsychological Development and Functional Outcome Sin Children With Hirschsprung Disease at School Age
Hirschsprung's disease (HD) is a rare congenital disease (1:5000) characterized by neonatal functional low bowel obstruction that is caused by aganglionosis of the distal bowel.
- Trial name
- Hirschsprung (NCT03406741)
- Testing
- psychometric evaluation, neuropsychological evaluation
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Autism Spectrum Disorder
Development of a Parent-mediated Mobile App Intervention for Parents of Children With Autism Spectrum Disorder Participating in an Adapted Horseback Riding Program
The purpose of this exploratory sequential mixed methods study is to develop and refine a parent-mediated mobile app intervention focused on improving the motor outcomes of children with autism spectrum disorder (ASD)…
- Trial name
- NCT05689541
- Testing
- Mobile app intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder
The Therapeutic Effect of TBS Stimulation on Emotion Regulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of intermittent theta burst stimulation over left dorsolateral prefrontal cortex on emotion regulation in autism spectrum disorder
- Trial name
- NCT04987541
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Growth Hormone Deficiency
Phase 2 Study of LUM-201 in Children With Growth Hormone Deficiency (OraGrowtH210 Trial)
This is a multi-national trial. The goals of the trial are to study LUM-201 as a possible treatment for Pediatric Growth Hormone Deficiency (PGHD) and investigate a predictive enrichment marker (PEM) strategy to select subjects…
- Trial name
- OraGrowtH210 (NCT04614337)
- Testing
- LUM-201, rhGH Norditropin® pen (34 µg/kg)
- Where
- 43 sites in United States, Australia and 4 more
- Volunteers
- 104 people
- Sponsor
- Lumos Pharma
Developmental Coordination Disorder
Effect of tDCS on Postural Control of Children With DCD
This study investigates the effects of Transcranial Direct Current Stimulation (tDCS) on postural control of children with Developmental Coordination Disorder (DCD).
- Trial name
- NCT03892083
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Moderate and Severe Undernutrition
Transition to Scale of Nutrition and Psychosocial Stimulation Program for Malnourished Children
We hypothesize that it is feasible to integrate a program of Nutritional Care and Pychosocial Stimulation into the Community Clinics in Bangladesh and thereby improve malnourished children's growth and development after a year of…
- Trial name
- TTS Bangladesh (NCT02208531)
- Testing
- Psychosocial Stimulation and Nutritional Care
- Where
- Bangladesh
- Volunteers
- 6,400 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Motor Delay
Effects of Conventional Physical Therapy With and Without Cuevas Medek Exercises in Developmental Delay
There are several etiologies for developmental delay (DD). One of the main causes of developmental delay is cerebral palsy (CP), which has a variety of clinical characteristics brought on by damage to the developing brain.
- Trial name
- NCT06522451
- Testing
- conventional physical therapy, Conventional physical therapy along with cuevas medek exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Autism
Validation of Indiana's Early Evaluation Hub System
The investigators' objective is to test an innovative method of autism diagnosis that integrates clinical evaluation and assessment of biobehavioral markers in a large high-risk community-referral sample of children in the…
- Trial name
- EAER21 (NCT06586788)
- Testing
- Eyelink Portable Duo, Integrated PCP Diagnosis and Eye-tracking Biomarker
- Where
- 7 sites in United States
- Volunteers
- 154 people
- Sponsor
- Indiana University
Growth & Development, Child Development
Resident Surveillance of Pediatric Patient Developmental Status at the Two Month Preventive Care Visit
The purpose of this study is to evaluate the efficacy of individualized performance feedback coupled with an educational module in improving resident performance of the physical and developmental examination component of…
- Conditions
- Growth & Development, Child Development, Internship and Residency, Education, Medical
- Trial name
- NCT00465361
- Testing
- performance feedback with an educational module
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Children's Mercy Hospital Kansas City
Fragile X Syndrome
Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X Syndrome
The purpose of this study is to determine whether Lovastatin, Minocycline and the combination Lovastatin/Minocycline are effective in treating behavioral symptoms in Fragile X individuals.
- Trial name
- LovaMiX (NCT02680379)
- Testing
- Minocycline, then Minocycline/Lovastatin, Lovastatin, then Minocycline/Lovastatin
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Université de Sherbrooke
Autism Spectrum Disorder, Self-Injurious Behavior
Deep Brain Stimulation in Children With Autism
The purpose of this study is to evaluate the safety and possible effectiveness of deep brain stimulation (DBS) of the nucleus accumbens in children with autism spectrum disorder and treatment-refractory, repetitive self-injurious…
- Trial name
- NCT03982888
- Testing
- Deep Brain Stimulation, DBS
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- The Hospital for Sick Children
Hypochondroplasia
An Interventional Study of Infigratinib in Children With Hypochondroplasia
ACCEL2/3 is a Phase 2/3 study. The purpose of the Phase 2 portion of the study (ACCEL2/3) is to evaluate the efficacy and safety of infigratinib in children with hypochondroplasia (HCH) receiving infigratinib at one of two doses…
- Trial name
- HCH (NCT06873035)
- Testing
- infigratinib 0.128 mg/kg/day, infigratinib 0.25 mg/kg/day
- Where
- 24 sites in United States, Australia and 8 more
- Volunteers
- 24 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Intellectual Disability, Intellectual Disability, Mild
Therapeutic Play in Children With Mild Intellectual Disability
The aim of this study is to determine the effectiveness of a designed therapeutic play activities program on improving motor adaptive behavior in a sample of Egyptian children with mild intellectual disabilities.
- Conditions
- Intellectual Disability, Intellectual Disability, Mild, Motor and Developmental Delay, Motor Delay
- Trial name
- NCT06735482
- Testing
- Therapeutic play program
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Beni-Suef University
Down Syndrome, Gross Motor Delay
Up, Down, and All Around: Evaluating Mobility Devices for Young Children With Developmental Disabilities and Delays
This research study will examine young children with Down syndrome's initial experiences with mobility devices. Children's biomechanics and exploration will be quantified while they are using both an overground partial bodyweight…
- Conditions
- Down Syndrome, Gross Motor Delay, Cerebral Palsy
- Trial name
- NCT06591559
- Testing
- Permobil Explorer Mini, Portable Mobility Aid for Children (PUMA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Autism Spectrum Disorder
Treatment of Anxiety in Late Adolescents With Autism
Autism spectrum disorders (ASD) affect approximately 1.1% of late adolescents and young adults, making it one of the most common neurodevelopmental disorders.
- Trial name
- TALAA (NCT02977962)
- Testing
- Cognitive-Behavior Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Myopia, Accommodation Spasm
Effect of VR and Accommdation Relax on Controlling Myopia in Children
This study evaluates the effect of virtual reality and accommodation relax technique on controlling onset and development of myopia in school-aged children.
- Conditions
- Myopia, Accommodation Spasm, Children
- Trial name
- NCT03427697
- Testing
- Virtual reality and accommodation relax techniques in combination
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tongren Hospital