Clinical trials: Child Development Disorder
Hypothalamic Obesity, Hypothalamic Tumor
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant form of obesity have excess rates of metabolic sequelae compared to…
- Conditions
- Hypothalamic Obesity, Hypothalamic Tumor, Craniopharyngioma
- Trial name
- NCT06299891
- Testing
- Phentermine / Topiramate Extended Release Oral Capsule [Qsymia]
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Intellectual Disabilities (F70-F79), Down Syndrome (DS)
Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities
IDHEApp will implement various educational technology tools and work with the families, teachers and caregivers to increase physical activity (PA) and improve healthy eating.
- Conditions
- Intellectual Disabilities (F70-F79), Down Syndrome (DS), Autism Disorder
- Trial name
- IDHEAPP (NCT07101523)
- Testing
- mHealth
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorder
Different Dietary Practices in Children with Autism Spectrum Disorder
The aim of this study is to investigate the effects of gluten-free casein-free diet and feingold diet on gastrointestinal system (GI) symptoms , eating behavior and quality of life in children with autism spectrum disorder.
- Trial name
- NCT06852027
- Testing
- Different Dietary Practices
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Aydin Adnan Menderes University
Anxiety, Autism Spectrum Disorder
Aromatherapy for Anxiety Among Children With Autism Spectrum Disorder
This study evaluated the use of bergamot aromatherapy in the treatment of anxiety in a medical office setting among children who are diagnosed with an autism spectrum disorder. H
- Trial name
- NCT03818490
- Testing
- Bergamot Aromatherapy
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Childhood Obesity, Physical Activity
Development and Feasibility of an Intervention to Increase Physical Activity Among Young Children
The aim of this study is to develop, implement, and evaluate a novel intervention to increase physical activity and reduce sedentary behaviour among pre-school children, with the ultimate goal of reducing obesity among this age…
- Trial name
- NCT05754359
- Testing
- I'm an Active Hero (IAAH) Intervention Program
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Autism Spectrum Disorder (ASD)
SCI-210 in the Treatment of Children and Young Adults With AutismEvaluate the Safety, Tolerability and Efficacy of SCI-210 in Children With Autism Spectrum Disorder (ASD)
To evaluate the safety and efficacy of SCI-210 in the treatment of Autism Spectrum Disorders (ASD)
- Trial name
- NCT05182697
- Testing
- SCI-210, Oral CBD oil
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Neurothera Labs Inc.
Autism Spectrum Disorder
An Exploratory Clinical Study of a Low-dose Buprenorphine Patch for the Treatment of Autism Spectrum Disorders
This study evaluates the safety and efficacy of low-dose buprenorphine in patients with ASD by using standard ASD symptom assessment methods (e.g., SRS-2 and ABC) as well as AI-assisted analyses utilizing exploratory gaze…
- Trial name
- NCT06772324
- Testing
- NORSPAN Buprenorphine Transdermal Patchs for Very-low dose group, NORSPAN Buprenorphine Transdermal Patchs for Lower dose group, NORSPAN Buprenorphine Transdermal Patchs for higher dose group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Sixth Hospital
Child Development, Mother-Infant Interaction
Clinical Interventions to Mitigate Neurodevelopmental Risk
Family Nurture Intervention (FNI) has been shown to facilitate emotional connection and long-term child developmental progress in the NICU population.
- Conditions
- Child Development, Mother-Infant Interaction, Diabetes Mellitus, Gestational
- Trial name
- NCT04233489
- Testing
- Family Nurture Intervention (FNI)
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Columbia University
Language Development Disorders
Using Video Interaction Guidance (VIG) With Children Who Have Language Delays.
The study aims to explore whether the intervention Video Interactive Guidance (VIG) has an impact on the development of the language and sociocognitive skills of children aged between 2 and 5 with identified language delays.
- Trial name
- NCT06250218
- Testing
- Video Interactive Guidance (VIG)
- Volunteers
- 4 people
- Sponsor
- University of Sheffield
Down Syndrome, Trisomy 21
Executive Function Play Opportunities for Children With Down Syndrome
The Executive Function Play Opportunities (EXPO) study is a sequential, multiple assignment, randomized trial (SMART) evaluating adaptive caregiver-mediated intervention pathways for improving executive function (EF) in children…
- Trial name
- EXPO (NCT07792382)
- Testing
- EXPO, EXPO Extended, EXPO Foundations
- Where
- 2 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Colorado State University
Neuromotor Impairments, Cerebral Palsy
The FBRI VTC Neuromotor Research Clinic
The FBRI VTC Neuromotor Research Clinic was established and opened in May of 2013 to provide intensive therapeutic services to individuals with motor impairment secondary to neuromotor disorders. It is direct by Dr.
- Conditions
- Neuromotor Impairments, Cerebral Palsy, Microcephaly, Autism
- Trial name
- NCT03325946
- Testing
- ACQUIRE Therapy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Virginia Polytechnic Institute and State University
Autism Spectrum Disorder
Neurotherapy to Promote Emotion Recognition in Autism
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder, more prevalent than previously thought and heterogeneous in expression, though uniformly characterized by severe social disability.
- Trial name
- NCT03376373
- Testing
- neurofeedback
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Autism Spectrum Disorder (ASD
Monitoring Daily Mobility in Children With Autism
Children with autism spectrum disorder (ASD) often show motor abnormalities and sleep disturbances that affect behavior, learning, and family quality of life.
- Trial name
- SIMBA (NCT07519369)
- Testing
- placement of a wearable wrist sensor
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Sensitive Dentin, Hypomineralization Molar Incisor
BIOSILITACE AS A DESENSITIZING AGENTIN HMI
Molar-Incisor Hypomineralization (MIH) is a qualitative enamel defect caused by systemic hypomineralization that affects one to four first permanent molars, and may or may not involve incisors.
- Conditions
- Sensitive Dentin, Hypomineralization Molar Incisor, Pain
- Trial name
- BDAHMI (NCT07080645)
- Testing
- Pain Relieving, topical application
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Modified Atkins Diet, Autism Spectrum Disorder
Efficacy of MAD as add-on Therapy in Comparison With Standard of Care in Children With ASD
In general ketogenic diet is a recognized as an efficient non pharmacological treatment for children with refractory epilepsy. However, in the last decade, it has been tried for many neurological disorders in children including…
- Conditions
- Modified Atkins Diet, Autism Spectrum Disorder, Standard of Care
- Trial name
- NCT06315465
- Testing
- Modified Atkin's Diet with standard of care, Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Autism Spectrum Disorders
Multisite Study: Parental Training Using Video Modelling to Develop Social Skills in Children With Autism
This is a Brazilian multisite study to test the efficacy of an Applied Behavior Analysis (ABA) parent training using video modeling to teach parents of children with Autism techniques to apply to their children in order to…
- Trial name
- NCT02235467
- Testing
- ABA parent training
- Where
- Brazil
- Volunteers
- 67 people
- Sponsor
- Federal University of São Paulo
Autism
Neuropsychopathological Study of Autism
Autism or autism spectrum disorder (ASD) is a relatively common (0.3% in Taiwan), multi-factorial, genetically and clinically heterogeneous, childhood-onset neurodevelopmental disorder.
- Trial name
- NCT01677663
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorders
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
The purpose of the present study is to evaluate the tolerability and efficacy of the Sound To Sleep System™ in improving the sleep quality of children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02739321
- Testing
- Sound to Sleep System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Education
Effectiveness of an Early Reading Intervention for Young Children With Intellectual Disabilities Who Need or Use Augmentative and Alternative Communication
The goal of this 2x2 factorial randomized controlled trial is to evaluate the effectiveness of two literacy interventions delivered at different time points, in kindergarten and in first grade, on the development of literacy…
- Trial name
- NCT07116200
- Testing
- Early Literacy Intervention in Kindergarten, Literacy Intervention in First Grade
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Ostfold University College