Clinical trials: Child Development Disorders, Pervasive
Autism
Neurophysiological Molecular and Developmental Analysis of the Glutamate Synapse in Autism
Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism
- Trial name
- NMDA-Autism (NCT01770548)
- Testing
- analysis of the glutamate synapse in autism, DNA collection, Auditory evoked potentials
- Where
- 4 sites in France
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorder
SPARK Exercise Program and Game-based Training in Children With Autism Spectrum Disorder
This randomized controlled trial (RCT) will compare the effects of the SPARK program versus game-based circuit training on motor skills and social interaction in 22 children with Autism Spectrum Disorder (ASD) aged 5-12 years.
- Trial name
- NCT07579000
- Testing
- Structured Sports, Play, and Active Recreation for Kids Exercise program (SPARK), Game-based Training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Autism, Cognition Disorder
The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism
This study will test whether donepezil (Aricept(Registered Trademark)), a drug that is approved by the Food and Drug Administration to treat Alzheimer's disease, can increase rapid eye movement (REM) sleep in children with autism…
- Trial name
- NCT00695136
- Testing
- Donepezil hydrochloride, Increase REM sleep percentage
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
ASD I, ASD2
Documenting Toothbrushing Experiences of Caregivers Who Care for Children With Autism Spectrum Disorders
The objective of this study is to examine caregiver reactions to the use of the hum by Colgate Smart Kids Toothbrush and associated app by children with autism spectrum disorder (ASD).
- Trial name
- humBrush (NCT05552144)
- Testing
- Hum by Colgate Smart Kids Toothbrush (battery powered) - 490000006871
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Colgate Palmolive
Autistic Disorder
Stellate Ganglion Block in Children With Autistic Disorder
The goal of this clinical trial is to explore efficacy of stellate ganglion block Children with Autistic Disorder. The main question it aims to answer is: Can stellate ganglion block improve the Autistic Disorder in children?…
- Trial name
- NCT06319599
- Testing
- Routine therapy, Stellate ganglion block, Lidocaine hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Autism Spectrum Disorder, Social Communication Challenges
Promoting Inclusive Educational Environments for Children with Autism and Other Social-communication Challenges: Preschool Class and Primary School
This study evaluates the effect of using the Autism Program Environment Rating Scale (APERS) as the foundation for providing feedback, in-service training and coaching to teachers, to improve program quality for autistic (ASD)…
- Trial name
- NCT05509309
- Testing
- APERS-based model
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Physical Exercise, Sleep Disturbance
Treatment of Sleep Disturbance in Children With ASD
This RCT study aims to compare effectiveness physical exercise and melatonin supplement on treating sleep disturbance in children with ASD.
- Conditions
- Physical Exercise, Sleep Disturbance, Autism Spectrum Disorder, Melatonin Deficiency
- Trial name
- NCT04878198
- Testing
- Jogging program, Melatonin supplement intervention
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Education University of Hong Kong
Autism Spectrum Disorder, Autism
Boston Outcomes of Autism in Toddlers Study
The purpose of this research study is to learn more about the outcomes of children who received an Autism Spectrum Disorder (ASD) diagnosis when they were toddlers.
- Trial name
- BOAT (NCT03517163)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder (ASD), Gastro-Intestinal Disorder
The Gut-Brain Study
The purpose of this study is to find out if transplant of fecal matter (stool), also known as fecal microbiota transplantation (FMT), from a healthy person into the intestines of children and young adults with Autism Spectrum…
- Trial name
- NCT03426826
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Los Angeles
Self-Injurious Behavior, Problem Behavior
Expanding Interventions for Automatically Maintained SIB
The goal of this clinical trial is to demonstrate feasibility of procedures and compare the outcomes of intervention arrangements to reduce sensory based self-injurious behavior exhibited by individuals with intellectual and…
- Conditions
- Self-Injurious Behavior, Problem Behavior, Intellectual Disability, Autism Spectrum Disorder
- Trial name
- NCT06739616
- Testing
- AUTOSIB across time, AUTOSIB diminished reinforcement
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Georgia
Autism Spectrum Disorder
Application of Fecal Microbiota Transplantation in Children With ASD
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. Intestinal microbial disturbance is common in children with ASD, and about 40% of ASD children suffer from gastrointestinal dysfunction.
- Trial name
- NCT04948814
- Testing
- Fecal microbiota transplantation, Vancomycin
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Autistic Disorder
Using a Voice Output Communication Aid to Facilitate Language Development in Young Children With ASD
It was proposed that in order to teach these children to use a Voice Output Communication Aid (VOCA), it should be introduced through a play-based situation using parents as the primary interventionist.
- Trial name
- NCT01816178
- Testing
- communication training
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Autism Spectrum Disorder
Satisfaction Rates Among Parents of Children With Autism in the ED
This study is a randomized controlled trial utilizing a patient-centered questionnaire distributed to parents of children with autism.
- Trial name
- ASD (NCT02675933)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Sleep Disorders, Autism Spectrum Disorder
Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders
The purpose of this study is to verify the efficacy of NPC-15 (melatonin 1 mg/d or 4 mg/d) versus placebo to sleep latency with electronic sleep diaries.
- Trial name
- NPC-15-5 (NCT02757066)
- Testing
- NPC-15 Granules Lower Dose, NPC-15 Granules Higher Dose
- Volunteers
- 196 people
- Sponsor
- Nobelpharma
Autism Spectrum Disorder
Pilot Study to Improve Access to Early Intervention for Autism in Africa
This Mentored Career Development Award will lay the foundation for a career focused on addressing two Grand Challenges in Global Mental Health priorities: 1) improving child access to evidence-based mental health care, and 2)…
- Trial name
- NCT02751957
- Testing
- Early Start Denver Model
- Where
- South Africa
- Volunteers
- 26 people
- Sponsor
- Duke University
Autism Spectrum Disorder, Autism
Efficacy of Reading Intervention on the Brain Connectivity in Autism
The overarching goal of this proposal is to test the impact of a comprehensive reading intervention program (Visualizing and Verbalizing) on changing the neurobiological mechanisms underlying reading comprehension deficits in…
- Conditions
- Autism Spectrum Disorder, Autism, Reading Problem
- Trial name
- BrainREAD (NCT05568056)
- Testing
- Visualizing and Verbalizing for Language comprehension and Thinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Autism Spectrum Disorder
Development and Evaluation of a Parent-led Intervention Module for Early Autism Spectrum Disorder (PRIME-ASD) in Odisha, India: Protocol for a Multiphase Mixed-methods Study Including an Open-label Randomised Controlled Trial
Many families of young children with autism in India wait a long time for a diagnosis and specialist therapy, and receive little structured guidance on how to help their child at home.
- Trial name
- NCT07858383
- Testing
- Behavioral: PRIME-ASD (Parent-led Intervention Module for Early Autism Spectrum Disorder), Behavioral: PRIME-ASD; Other: Treatment as usual
- Volunteers
- 188 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Insomnia, Autism
Sleep in Children With Autism and Intellectual Disability
Purposes: Establish proof-of-concept for home polysomnography in the assessment of sleep disorders among prepubertal school children with autism and intellectual disabilities combined; To explore the diagnostic yield of…
- Conditions
- Insomnia, Autism, Intellectual Disability
- Trial name
- SLEEP-AID IT (NCT06403969)
- Testing
- Applied Behavior Analysis
- Volunteers
- 15 people
- Sponsor
- Värmland County Council, Sweden
Autism Spectrum Disorder
Multisensory Room in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a complex neurological development with onset in infancy or early childhood. Atypical sensory processing has been widely reported in ASD, and recent literature suggest that this abnormality…
- Trial name
- NCT06184802
- Testing
- TAU+Multisensory room, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autism Spectrum Disorder
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
ML-004-002 is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study that will enroll approximately 150 adolescent and adult subjects with ASD.
- Trial name
- NCT05081245
- Testing
- ML-004 (IR)/(ER) tablet
- Where
- 29 sites in United States, Australia and 1 more
- Volunteers
- 168 people
- Sponsor
- MapLight Therapeutics
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