Clinical trials: Child Growth
Short Children Born Small for Gestational Age (SGA)
Long-term Safety Follow-up After Growth Hormone Treatment of Short Children Born Small for Gestational Age
This study is performed as part of the Marketing Authorisation Holder's post-marketing pharmacovigilance plan to investigate the long-term safety, in particular the diabetogenic potential and immunogenicity of rhGH therapy in…
- Trial name
- SGA (NCT01491854)
- Testing
- Bloodsampling
- Where
- 23 sites in Czechia, Georgia and 4 more
- Volunteers
- 130 people
- Sponsor
- Sandoz
Acute Gastroenteritis
Prevalence of Anemia and Growth Assessment in Acute Gastroenteritis
1. Assessment of the growth parameters in infants admitted with acute gastroenteritis. 2. Determine the prevalence of anemia in infants admitted with acute gastroenteritis.
- Trial name
- NCT06038305
- Where
- Egypt
- Volunteers
- 297 people
- Sponsor
- Assiut University
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
The purpose of this study is to pilot the use of Insulin-Like Growth Factor-1 (IGF-1) treatment in 22q13 Deletion Syndrome (Phelan-McDermid Syndrome) caused by SHANK3 gene deficiency in order to evaluate safety, tolerability, and…
- Trial name
- NCT01525901
- Testing
- Insulin-Like Growth Factor-1 (IGF-1), Normal saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Healthy
Effect of DHA Supplementation on Cognitive Performance and Growth in Chinese Children
The purpose of this study is to determine whether DHA supplement (in a daily dose of 300 mg) will improve the cognitive performance, associated metabolism and growth in normal children aged 6-12 years in primary schools.
- Trial name
- NCT02308930
- Testing
- Vitamins + DHA supplement (Vitamins A,D, E and algal oil), Vitamins supplement (Vitamins A,D, E and corn oil)
- Volunteers
- 106 people
- Sponsor
- Sun Yat-sen University
Osteoporosis, Osteopenia
Encouraging Calcium Absorption and Bone Formation During Early Puberty
Increasing bone mass during puberty can ultimately decrease the risk of developing osteoporosis, which causes bones to weaken and break more easily later in life.
- Trial name
- NCT00022867
- Testing
- Nondigestible oligosaccharide (NDO)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Early Onset Scoliosis
Evaluation of a Modern System to Allow for Growth in Children With Scoliosis Versus a Conventional Treatment
The foremost challenge when managing early onset scoliosis (curve deformity before the age of 10) is to prevent curve progression while maintaining growth of the spine.
- Trial name
- NCT01672749
- Testing
- Growth guiding construct using TROLLEY system, Spine based dual growing rod or rib based VEPTR
- Where
- 3 sites in Switzerland, United Kingdom
- Volunteers
- 18 people
- Sponsor
- AO Innovation Translation Center
Growth Retardation
Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children
1. To further evaluate the safety and efficacy of PEG-Somatropin in the treatment of children with growth hormone deficiency for a relatively long period 2.
- Trial name
- NCT03290235
- Testing
- PEG-somatropin
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Diagnosis of GHD With IGF-I/IGFBP-3 Ratio
Growth Hormone (GH) Deficiency & Insulin Like Growth Factor 1 (IGF-I)/ Insulin Like Growth Factor Binding Protein 3 (IGFBP-3) Ratio
A 35-month cross-sectional observational study was conducted at an outpatient university hospital in Amman, Jordan. We obtained a comprehensive medical and laboratory evaluation for 134 short-statured children (64 boys and 70…
- Trial name
- NCT02424240
- Testing
- IGF-1/IGFBP-3 ratio
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Growth and Development
Validation of a Smart Phone App to Non-invasively Measure the Size of Children
Smart phones are omnipresent. Apps exist to calculate size of medical equipment and doses of medication if a valid weight or age is entered. During emergency situations, these values are often unknown.
- Trial name
- NCT02805192
- Testing
- Size Measurement by a Smart phone App
- Where
- Switzerland
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Stunting
Characterisation and Sociodemographic Determinants of Stunting Among Malaysian Children Aged 6-19 Years
Child stunting remains an important global health issue, with 157 million children under five years of age estimated to be stunted in 2014.
- Trial name
- NCT03364426
- Testing
- No intervention
- Volunteers
- 6,759 people, healthy volunteers welcome
- Sponsor
- Manjinder Sandhu
Child Development, Growth
Health and Early Life Microbiota
The aim of this cohort is to identify environmental, lifestyle and genetic factors that modify the human intestinal microbiota development during the first years of life, and to identify early microbiota features that associate…
- Conditions
- Child Development, Growth, Allergy, Overweight
- Trial name
- HELMi (NCT03996304)
- Where
- Finland
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Moderate Acute Malnutrition, Stunting
Eggs for Gut Health
The goal of this clinical trial is to test egg powder supplementation in children with moderate acute malnutrition in Sierra Leone.
- Conditions
- Moderate Acute Malnutrition, Stunting, Environmental Enteric Dysfunction, Severe Acute Malnutrition
- Trial name
- NCT06002438
- Testing
- Whole egg powder, Corn powder, Supercereal Plus
- Where
- 10 sites in Sierra Leone
- Volunteers
- 461 people
- Sponsor
- Washington University School of Medicine
Growth Hormone Deficiency, Pediatric, Endocrine System Diseases
A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial
A multicenter, phase 3, long-term extension trial of TransCon hGH administered once-weekly in children with growth hormone deficiency (GHD) who previously participated in a phase 3 TransCon hGH trial.
- Conditions
- Growth Hormone Deficiency, Pediatric, Endocrine System Diseases, Hormone Deficiency, Pituitary Diseases
- Trial name
- enliGHten (NCT03344458)
- Testing
- TransCon hGH
- Where
- 42 sites in United States, Armenia and 9 more
- Volunteers
- 298 people
- Sponsor
- Ascendis Pharma A/S
Pollutant Effects in the Growth and Development
Environment and Childhood Project Based on a Multicentric Mother-child Cohort of Spain
INMA - INfancia y Medio Ambiente [Environment and Childhood] Project is a research network of several Spanish groups that created a project with the aim to study the paper of the more relevant environmental pollutants in the air…
- Trial name
- INMA (NCT03352960)
- Where
- Spain
- Volunteers
- 2,957 people
- Sponsor
- Basque Health Service
Growth Hormone Deficiency
National Cooperative Growth Study in CKD
The purpose of this study is to learn whether growth hormone being administered to children with Chronic Kidney Disease is effective and if it has any side effects.
- Trial name
- NCGS (NCT00616278)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Davis
Obesity
Keys to Healthy Family Child Care Homes
The purpose of this project is to evaluate the efficacy of a 9-month Family Child Care Home (FCCH)-based intervention, Keys to Healthy Family Child Care Homes, to increase the physical activity and improve the diet quality of…
- Trial name
- NCT01814215
- Testing
- Keys to Healthy Family Child Care Homes
- Where
- 2 sites in United States
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Appetite Disorders
Effect of Zinc Supplementation on Appetite and Growth in Primary Malnourished Children
Zinc supplementation effect on appetite and growth of malnourished children
- Trial name
- NCT03098810
- Testing
- Zinc sulphate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University