Clinical trials: Children Under General Anaesthesia
Children Under General Anesthesia
Target-controlled Infusion of Propofol for Induction of Pediatric Anesthesia
The purpose of this study is to determine a effect-site concentration of propofol in children 3 to 11 years effective to make a induction of general anesthesia.
- Trial name
- NCT01411020
- Testing
- endotracheal intubation
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Bite Force, Masseter Muscle
Postoperative Bite Force After Bioflx and Zirconia Crowns in Children
This randomized clinical trial aims to compare postoperative bite force following full-crown restoration with preformed Bioflx and zirconia crowns in children undergoing comprehensive dental treatment under general anesthesia.
- Conditions
- Bite Force, Masseter Muscle, Zirconia Crowns, Primary Molars
- Trial name
- NCT07825103
- Testing
- Preformed Bioflx Crown, Preformed Zirconia Crown
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Reference Values
Reference Values for Pulse Induced Continuous Cardiac Output (PiCCO) Variables in Children
Pulse induced continuous cardiac output (PiCCO) is an established technology for measurement of advanced hemodynamic variables in critically ill patients.
- Trial name
- NCT01283529
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Anesthesia, General, Sevoflurane
Frequency Analysis of Raw EEG During Sevoflurane Anesthesia in Children Younger Than 2 Years Old
The purpose of this study is to analyze raw electroencephalogram in infants younger than 2 years old undergoing general anesthesia using sevoflurane.
- Conditions
- Anesthesia, General, Sevoflurane, Infant
- Trial name
- NCT05148065
- Testing
- BIS, PSi
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Sang-Hwan Ji
Quality of Life
Assessment of Oral Health Related Quality of Life After Full Mouth Rehabilitation Under GA
To assess Oral health related quality of life (OHRQOL) after full mouth rehabilitation under GA in a group of Egyptian children with special healthcare need.
- Trial name
- NCT03497312
- Testing
- full mouth rehabilitation
- Volunteers
- 14 people
- Sponsor
- Cairo University
Full Mouth Rehabilitation, Canine Overlap Relation
Canine Occlusal Relationship Changes After Stainless-Steel Crown Placement Under General Anesthesia
The aim of the study is to Assess and compare canine occlusal relation in children with carious primary molars before they are treated by stainless steel crowns under general anaesthesia and after their placement, evaluate the…
- Conditions
- Full Mouth Rehabilitation, Canine Overlap Relation, General Anesthesia
- Trial name
- NCT04731337
- Testing
- Digital Caliper (Shenzhen Jiabaili Electronic Commerce Co., Ltd)
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Cairo University
Surgery
Comparison of Blood Pressure Measurements in Upper and Lower Extremities in Children Under General Anesthesia
There is very little information comparing non-invasive blood pressure (BP) readings obtained from upper and lower limbs, as well as comparing invasive and non-invasive blood pressures in the children under anesthesia.
- Trial name
- NCT03220906
- Testing
- Blood pressure measurement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nationwide Children's Hospital
Pain
Functional Near Infrared Spectroscopy to Detect Pain in Young Children Under General Anesthesia
This is a three-phase pilot prospective study to develop a devise capable of detecting changes in cortical blood volume and oxygenation due to noxious stimuli.
- Trial name
- NCT04362423
- Testing
- fNIRS
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Intraocular Pressure
Effect of Sevoflurane Concentration on Intraocular Pressure in Surgical Children With Healthy Eyes
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01248689
- Testing
- concentration profile 1, concentration profile 2, concentration profile 3
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Distal Forearm Fracture, Distal Radius Fracture
Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia?
Treatment of displaced distal forearm fractures (DFF) in children have traditionally been closed reduction and pin fixation, although they might heal and remodel without manipulation, with no functional impairment.
- Trial name
- CASTING (NCT05736068)
- Testing
- Non-surgical treatment, Surgical treatment
- Where
- 4 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
General Anesthesia
Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference…
- Trial name
- NCT05275309
- Testing
- Exploration of optimal PEEP in supine and prone position
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Endotracheal Extubation, Airway Anesthesia
BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia
During surgery, anaesthetists can use an endotracheal tube (ETT) to facilitate ventilation. At emergence from general anaesthesia, there are two techniques for removal of the ETT: (1) the ETT is removed when the child is waking…
- Conditions
- Endotracheal Extubation, Airway Anesthesia, Paediatric
- Trial name
- BELUGA (NCT07204990)
- Testing
- Direct removal of endotracheal tube, Laryngeal mask airway inserted following deep extubation
- Where
- 8 sites in United States, Australia and 4 more
- Volunteers
- 1,400 people
- Sponsor
- Telethon Kids Institute
Anesthetics, Inhalation, Neuromuscular Blockade
Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Sugammadex is the first selective relaxant binding agent approved to reverse certain non-depolarizing neuromuscular drugs in patients 2 years old and above.
- Conditions
- Anesthetics, Inhalation, Neuromuscular Blockade, Anesthesia, General
- Trial name
- NCT03795259
- Testing
- Rocuronium, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Quality of Life, General Anesthesia
Assessment of Changes in Oral Health-related Quality of Life , Oral Hygiene Status and Body Growth in CSHCN Following Dental Treatment Under General Anaesthesia
evaluation of the impact of dental treatment under GA on oral health-related quality of life (OHRQoL) in children with SHCN with severe dental caries with Assessment in change in oral health status and the impact on children's…
- Conditions
- Quality of Life, General Anesthesia, Children With Special Health Care Needs, Body Mass Index
- Trial name
- NCT04861675
- Testing
- Full mouth rehabilitation under general anaesethia
- Volunteers
- 10 people
- Sponsor
- Cairo University
Pediatric Dentistry
Change in Quality of Life After Full Mouth Rehabilitation Under General Anesthesia in a Group of Egyptian Children With Down Syndrome
To assess oral health related quality of life (OHRQOL) after full mouth rehabilitation under GA in a group of Egyptian children with down syndrome .
- Trial name
- NCT05146271
- Testing
- Complete mouth rehabilitation under general anesthesia in a group of Egyptian children with Down syndrome
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Children, Heart Diseases
Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia
What is the optimal maintenance dose of remifentanil to ensure apnoea, during breath hold episodes in children having cardiac MR imaging with general anaesthesia?
- Conditions
- Children, Heart Diseases, Anaesthesia, Magnetic Resonance Imaging
- Trial name
- NCT02481791
- Testing
- Remifentanil and/or propofol, propofol
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Preoperative Anxiety
Effect of a Preparation Video on Preoperative Anxiety in Children Undergoing Dental Treatment Under GA
The present study investigated the effect of an animated preoperative preparation video in mitigating preoperative anxiety among children receiving comprehensive dental treatment under General Anesthesia (GA).
- Trial name
- NCT06612398
- Testing
- Preoperative preparation video
- Where
- Jordan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulmonary Ventilation
Comparison of Ventilation Tubes Among Anesthetized Pediatrics
To discover whether different types of ventilation breathing tube influence ventilation effect of children/ neonate, the investigators analysis tidal volume, end tidal carbon dioxide, compliance among children and neonate under…
- Trial name
- NCT03822689
- Testing
- Ventilator breathing tube F2220, Ventilator breathing tube F2216, Ventilator breathing tube F1520
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital