Clinical trials: Children With Neurodevelopmental Disorders
Autistic Disorder
Safety and Effectiveness of D-Cycloserine in Children With Autism
This study will determine the effectiveness of D-cycloserine in reducing symptoms of autism in autistic children.
- Trial name
- NCT00198120
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Attention Deficit Disorder With Hyperactivity
Clonidine in Attention Deficit Hyperactivity Disorder (ADHD) in Children
The purpose of this study is to determine the safety and efficacy of clonidine alone or in combination with methylphenidate for children 7-12 years of age with attention-deficit, hyperactivity disorder.
- Trial name
- NCT00031395
- Testing
- clonidine, methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Cincinnati
CTNNB1 Gene Mutation
Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation
The aim of this study is to explore and define the correlations between genotype and phenotype in patients with CTNNB1 mutations as well as monitor and survey the natural history of the CTNNB1 syndrome.
- Trial name
- Gen-Phe CTNNB1 (NCT04812119)
- Testing
- The Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F), The Autism Spectrum Quotient-Children's Version (AQ-Child), The Autism-Spectrum Quotient (AQ)-Adolescent Version (AQ-Adolescent)
- Where
- 3 sites in Australia, Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Attention-deficit, Prematurity
Early Childhood Attention Battery in Preterm Children
The aims of this project are: 1. To explore, using the ECAB, if and in which measure the attentional abilities of young preterm children are different from term peers, whom reference data are already published27. 2.
- Trial name
- NCT05843266
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Autism
Trial of Propranolol in Adults and Adolescents With ASD and Predictors of Response
The purpose of this study is to explore the effects of propranolol on social interaction, and secondarily on language, anxiety, adaptive behaviors, and global function in high functioning adults and adolescents with autism in a…
- Trial name
- NCT02414451
- Testing
- Propranolol
- Sponsor
- University of Missouri-Columbia
Autism Spectrum Disorder, Gastro-Intestinal Disorder
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Autism-spectrum disorder with Gastrointestinal disorders (constipation, diarrhea, and/or abdominal pain).
- Conditions
- Autism Spectrum Disorder, Gastro-Intestinal Disorder, Constipation, Diarrhea
- Trial name
- NCT06503978
- Testing
- MTP-101P, Vancomycin, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Gut-Brain-Axis Therapeutics Inc.
Fetal Alcohol Spectrum Disorder
Parenting Training for Children With FASD
Prenatal alcohol exposure can lead to a myriad of adverse developmental outcomes in children, and is the leading cause of mental disability in Canada.
- Trial name
- SF-FASD (NCT02210455)
- Testing
- Strongest Families FASD intervention, Psychoeducation
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- IWK Health Centre
Tic Disorder, Childhood
Acupuncture Treament in Children With Tic Disorders
This study intends to evaluate the efficacy of acupuncture on tic disorders in Children; and to explore the underlying mechanism of acupuncture intervention on tic disorders based on Magnetic Resonance Diffusion Tensor…
- Trial name
- NCT07588815
- Testing
- Acupuncture, Comprehensive Behavioral Intervention for Tics (CBIT)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Meizhou People's Hospital
Attention Deficit Hyperactivity Disorder Combined
Evaluating the Feasibility of FAM-SOTC Intervention for Families of Adolescents With ADHD: Pilot Study
Attention-deficit/hyperactivity disorder (ADHD), is a highly genetic and complex neurological disorder, where disruptive behavior, emotional imbalance, and lack of attention can interrupt with normal development of adolescents…
- Trial name
- NCT04378517
- Testing
- psychosocial education in parents groups, psychosocial parents support, interviews with APN
- Where
- Iceland
- Volunteers
- 23 people
- Sponsor
- University of Iceland
Attention Deficit Disorder With Hyperactivity, Attention-Deficit-Disordered Children
Evaluation of a Parent/Child Cognitive-Behaviorial Therapy Program in ADHD Children With Emotional Dysregulation Profile
Attention Deficit Disorder (ADD) with or without Hyperactivity/Impulsivity (ADHD) is a neurodevelopmental syndrome that has a lasting impact on the child's daily lifestyle and leads to functional impairment.
- Trial name
- DP-KID (NCT03176108)
- Testing
- Cognitive Behavorial Therapy (CBT), Body mediation
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Montpellier
Developmental Disability, Intellectual Disability
Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities
Children with intellectual/developmental disabilities (ID/DD) will experience less dental anxiety and cooperate better in a Sensory Adapted Dental Environment (modified visual, sensory, and somatosensory stimuli in a regular…
- Conditions
- Developmental Disability, Intellectual Disability, Dental Anxiety
- Trial name
- NCT03218462
- Testing
- Sensory Adapted Dental Environment (SADE)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Virginia Commonwealth University
Bipolar Disorder, Bipolar I Disorder
Children's Bipolar Network Treatment Trial I
This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN).
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Other Specified Bipolar and Related Disorder
- Trial name
- CBN (NCT05427123)
- Testing
- Medication or psychosocial treatment
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Neurodevelopmental Disorders
KneuroKnits: Participation and Anxiety in People With Neurological Conditions Participating in a Knitting Group
The reported social benefits of knitting combined with the urgent need for social and activity-based programs in the disability community suggest that a knitting intervention may fill a substantial gap in available programs.
- Conditions
- Autism Spectrum Disorder, Neurodevelopmental Disorders, Acquired Brain Injury, Physical Disability
- Trial name
- NCT04639570
- Testing
- KneuroKnits
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Attention Deficit/Hyperactivity Disorder
A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder.
To evaluate long-term safety exposure
- Trial name
- NCT05279313
- Testing
- Centanafadine Hydrochloride
- Where
- 86 sites in United States, Canada and 1 more
- Volunteers
- 680 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism Spectrum Disorder
Dietetic Pattern in Children With Autism Spectrum Disorders
To date, it is well documented that the gut microbiota (GM) influences numerous physiological processes in the healthy "host". The alteration of the composition and function of the intestinal microbiota, commonly referred to as…
- Trial name
- NCT04719923
- Testing
- Children with autism spectrum disorders
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Autism Spectrum Disorder
Study of the Visual Perception During Emotional States on Subjects With an Intrusive Disorder of the Development
The Pervasive Developmental Disorders (PDD) are severe neurodevelopmental disorders, affecting nearly 1% of the general population.
- Trial name
- VisioTED (NCT02827279)
- Testing
- emotional induction
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism, Autism Spectrum Disorder
Advanced Social Relations Training
Advanced social relations protocol is aimed at young people with autism aged 9-12 years with an intelligence quotient (IQ) ≥ 80.
- Trial name
- NCT06342583
- Testing
- Advanced social relations training with technical device, Advanced social relations training without technical device
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism, Neurodevelopment
Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals
Many people with autism and other developmental conditions have difficulty speaking or do not use speech and need other ways to communicate.
- Trial name
- AAC (NCT07581483)
- Testing
- Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support
- Where
- 2 sites in United States, Kenya
- Volunteers
- 500 people
- Sponsor
- Indiana University
Autism Spectrum Disorder
Effectiveness of Visual-Behavioral Approach and Predictive Factors in Dental Exams for Children With Autism
The objective of the study are: 1. Evaluating the effectiveness of the structural-visual model of behavioral approach on the compliance and cooperativity of children with ASD in dental examinations. 2.
- Trial name
- NCT06470724
- Testing
- Structural visual approach
- Where
- Indonesia
- Volunteers
- 37 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Autism Spectrum Disorder, Intellectual Disability
Effectiveness of Music Therapy in Social Skill Intervention for Children With ASD/ID
Autism spectrum disorder (ASD) is a developmental impairment characterized by persistent deficits in social communication and interactions.
- Trial name
- NCT04557488
- Testing
- Music therapy, Behavioral-based social skill training
- Where
- Hong Kong
- Volunteers
- 77 people
- Sponsor
- Education University of Hong Kong
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