Clinical trials: China
Neonatal Diabetes, Monogenic Diabetes
China Monogenic Diabetes Registry
This observational study aims to establish a digital registry, screening platform for patients with monogenic diabetes using internet-based and mobile application technologies.
- Conditions
- Neonatal Diabetes, Monogenic Diabetes, Maturity Onset Diabetes of the Young
- Trial name
- CMDR (NCT07492004)
- Testing
- No Interventions
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Tianjin Medical University General Hospital
Pulmonary Hypertension, Pregnancy, High Risk
Pregnant Women With Pulmonary Hypertension in China
Little is known about the status of maternal, obstetric and neonatal complications and the potential predictors of developing heart failure (HF) in the mothers with pulmonary hypertension in China.
- Trial name
- NCT05198206
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Obesity Prevention
Effects of an Adolescent Physical Activity Promotion Model on Physical Activity in Obese Chinese Children.
The purpose of this study was to evaluate the effectiveness of an intervention program based on the Youth Physical Activity Promotion Model (YPAP) in increasing physical activity levels among overweight and obese children in…
- Trial name
- NCT06631833
- Testing
- Intervention measures based on the YPAP model.
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Intestinal Infection, Clostridioides Difficile Infection
Rescue Fecal Microbiota Transplantation for National Refractory Intestinal Infections
A national data registry of patients receiving the rescue fecal microbiota transplantation for the refractory intestinal infections from the China Microbiota Transplantation System was designed to assess the short-term and…
- Conditions
- Intestinal Infection, Clostridioides Difficile Infection, Antibiotic-associated Diarrhea
- Trial name
- NCT03895593
- Testing
- rescue fecal microbiota transplantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Pregnant Women
Pregnancy Registry in West China
With the Healthy China 2030 Plan for further reducing maternal mortality ratio (MMR), and increasing number of high-risk pregnancies in China, we aimed to develop a registry of pregnant women based on hospital-based Electronic…
- Trial name
- NCT04607499
- Volunteers
- 53,667 people
- Sponsor
- West China Hospital
Type 2 Diabetes Mellitus
Multi-center, Single Arm, Observational Study to Evaluate the Safety of Dapagliflozin in Type 2 Diabetes Mellitus Patients in China
DONATE study is a multi-center, prospective cohort, single arm, observational study to be performed in 3000 Chinese type 2 diabetes mellitus (T2DM) patients recruited from 100 tier 2 or 3 hospitals, China.It is a drug intense…
- Trial name
- DONATE (NCT03156985)
- Where
- 83 sites in China
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Coronary Artery Bypass Grafting, Surgical Treatment for Heart Valve Diseases
China Cardiovascular Surgery Registry
China Cardiovascular Surgery Registry (CCSR) Study is a national database for coronary artery bypass grafting (CABG) and valve surgery performed in 87 hospitals with cardiovascular surgery volume > 100 per year.
- Trial name
- CCSR (NCT02400125)
- Where
- China
- Volunteers
- 90,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hepatitis E
A Clinical Trial to Evaluate a Recombinant Hepatitis E Vaccine in Healthy Adults
Hepatitis E is characteristic by sporadic and local epidemic around the world, and mainly infects adults aged 15 to 40 years old, resulting in the infection rate ranged from 1% to 15%.
- Trial name
- NCT02603055
- Testing
- 30μg/0.5ml Hepatitis E vaccine, 30μg/0.5ml Recombinant Hepatitis E vaccine
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Myopia, Environment
Environmental Factors and Myopia Prevalence Among Uyghur Students in Remote China
Ophthalmologic screening performs annually. Main information collected: gender, age, race, school, visual acuity, autorefractive results.
- Trial name
- NCT07119723
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
GASTROINTESTINAL NEOPLASMS
Longitudinal Study on the Evolution Trend and Influencing Factors of Postoperative Reflux of Esophageal Cancer Based on PEPTEST Technique
The goal of this observational study intends to explore the evolution trend and related factors of postoperative reflux of esophageal cancer based on PEPTEST detection, in order to identify postoperative reflux The main question…
- Trial name
- NCT06509022
- Testing
- PEPTEST test
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Primary Dystonia, Hemifacial Spasm
Movement Disorder Survey in East China
Movement disorder involve recurring or constant muscle contractions causing squeezing or twisting movement, such as hemifacial spasm, blepharospasm, cervical dystonias etc.
- Trial name
- MDS (NCT01168388)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Sir Run Run Shaw Hospital
Overweight, Obesity
Brain Breaks Exercise Videos for Overweight and Obese Children
This randomized controlled study evaluated the effects of a 4-week Brain Breaks® exercise video intervention on physical activity and Transtheoretical Model-related psychosocial factors among overweight and obese children and…
- Trial name
- NCT07826624
- Testing
- Video-Guided Physical Activity Program
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou University
Functional Gastrointestinal Disorders
Multi-center Study on Pediatric Functional Gastrointestinal Disorders in Mainland China
This study plans to understand the prevalence and clinical characteristics of pediatric functional gastrointestinal disorders in mainland China through multi-center investigation and clinical epidemiological analysis, to reveal…
- Trial name
- NCT04388137
- Testing
- No intervention.
- Volunteers
- 1,500 people
- Sponsor
- Zhejiang University
Chronic Thromboembolic Pulmonary Hypertension
Change-a Multi-center Chronic Thromboembolic Pulmonary Hypertension （CTEPH） Database in China
The Change Database is a prospective, observational multi-center disease registry, which will collect data on patients with chronic thromboembolic pulmonary hypertension (CTEPH) in China.
- Trial name
- NCT05311072
- Testing
- pulmonary endarterectomy or balloon pulmonary angioplasty
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Hemophilia
EPOCH-Economics and Patient Outcomes in China in Haemophilia
The overarching goal of the EPOCH project is to: Support a broad and robust needs assessment in the haemophilia space in China Measure the variability in the needs and care provision Generate outcome data (health economic…
- Trial name
- EPOCH (NCT07454239)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Child Development
Molecular Structure and Content of Human Milk Oligosaccharides (HMOs) and Its Effect on Infant Health in China
In the study, the composition and content of human milk oligosaccharides in premature delivery mothers in China will be examined to investigate the differences in oligosaccharide concentrations in preterm breast milk from…
- Trial name
- NCT04277260
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Acute Kidney Injury
China Collaborative Study on Epidemiology of Acute Kidney Injury
Acute kidney injury (AKI) is a common clinical syndrome, especially patients in the hospital. AKI has become a huge medical burden in China. Little information is available about this disease burden in our country.
- Trial name
- NCT03054142
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,000,000 people
- Sponsor
- XinLing Liang
Hypoxic Ischemic Encephalopathy, Cerebral Infarction
Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy
This study examines the effect of cord blood in the treatment of newborn infants with neonatal encephalopathy in combination with hypothermia, which is the standard treatment for this condition.
- Trial name
- NCT02551003
- Testing
- Autologous cord blood, Hypothermia
- Where
- China
- Sponsor
- Children's Hospital of Fudan University
Lupus Nephritis, Children
Multicenter Registry of Pediatric Lupus Nephritis in China
This study is designed to evaluate the efficacy and safety of the current treatment option and outcome of pediatric lupus nephritis patients in China.
- Conditions
- Lupus Nephritis, Children, Steroid, Immunosuppressive Treatment
- Trial name
- NCT03791827
- Testing
- Corticosteroid, Hydroxychloroquine, Cyclophosphamide
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Xiqiang Dang