Clinical trials: Chinese
Drug-resistant Tuberculosis, Pulmonary Tuberculosis
Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BDLL Chinese Cohort
This is an investigational, prospective, multicenter, single-arm, open label trial. The goal of this clinical trial is to evaluate the efficacy and safety of a 6-month all-oral regimen, consisting of Bedaquiline (BDQ, B)…
- Conditions
- Drug-resistant Tuberculosis, Pulmonary Tuberculosis, Rifampin-resistant Tuberculosis
- Trial name
- INSPIRE-BDLL (NCT06649721)
- Testing
- bedaquiline, delamanid, linezolid
- Where
- 34 sites in China
- Volunteers
- 120 people
- Sponsor
- Huashan Hospital
Early Puberty
the Association Between Obesity and Early Puberty
childhood obesity and early puberty are closely related, but existing reports usually focus on their relationship from the perspective of phenotype.
- Trial name
- NCT04317014
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Disease Control and Prevention
Obesity Prevention
Effects of an Adolescent Physical Activity Promotion Model on Physical Activity in Obese Chinese Children.
The purpose of this study was to evaluate the effectiveness of an intervention program based on the Youth Physical Activity Promotion Model (YPAP) in increasing physical activity levels among overweight and obese children in…
- Trial name
- NCT06631833
- Testing
- Intervention measures based on the YPAP model.
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Selenium Deficiency
Optimization of Selenoprotein P in Chinese Subjects
The purpose of this study is to determine the amount of selenium as selenomethionine that is required to optimize selenoprotein P in selenium-deficient Chinese subjects
- Trial name
- NCT00428649
- Testing
- 20 µg selenium, 40 µg selenium, 60 µg selenium
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Growth & Development, Brain
A First-ever Research Collaboration to Characterize MRI Measured Neural Flexibility Development in Chinese Toddlers
The overall objective is to characterize the developmental characteristics of MRI measured neural flexibility, as an index of cognitive flexibility, in Chinese toddlers (32 to 42 months old).
- Trial name
- NCT04916652
- Testing
- MRI
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cardiovascular Diseases, Dyslipidemias
NUTS for the Prevention of Cardiovascular Disease in Chinese Adults
This study evaluates the feasibility of walnuts supplementation among population of high CVD risks over a period of 6 months. 70 participants will be controls receiving non-edible gifts.
- Trial name
- NUTS (NCT04037943)
- Testing
- Walnuts 30 grams, Walnuts 60 grams
- Where
- China
- Volunteers
- 210 people
- Sponsor
- The George Institute for Global Health, China
Gaucher Disease
Efficacy and Safety of Eliglustat in Chinese Pediatric Patients With Gaucher Disease Type 1 and Type 3
Primary Objective: Evaluate the efficacy and safety of eliglustat in Chinese pediatric patients (≥12 to <18 years old) with Gaucher disease type 1 and type 3.
- Trial name
- NCT06523517
- Testing
- Eliglustat Tartrate Capsules
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Peking Union Medical College Hospital
Hypertension
The Chinese Early-onset Hypertension Study (CHESS)
Hypertension (HTN) is the most important cardiovascular risk factor which is responsible for 50% of cardiovascular morbidity and mortality, and also a substantial public health problem affecting approximately 1/4 of the adult…
- Trial name
- CHESS (NCT02819674)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
HPV Infections, Cervical Cancer
Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
The study will evaluate the immunogenicity and safety of 9-valent HPV recombinant vaccine in Chinese healthy females16 to 26 years of age.
- Conditions
- HPV Infections, Cervical Cancer, Vulvar Cancer, Vaginal Cancer
- Trial name
- NCT05372016
- Testing
- Experimental: Experimental: 9-valent Human Papillomavirus (Types 6, 11, 16, 18, 31, 33, 45, 52, 58), Active Comparator: GARDASIL ®9
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Type II Diabetes Mellitus
Evaluation of Innovated Screening Tools for Type 2 Diabetes Among Chinese Population(SENSIBLE STUDY I)
Evaluation of using 2h-UG combined with FPG, AGEsP alone or in combination with FPG in diabetes screening in Chinese natural population
- Trial name
- NCT03025919
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Dyslexia, Special Education
Multiple Family Narrative Therapy for Chinese Families of Children With Dyslexia
The goal of this randomized controlled trial (RCT) is to develop and to implement a multiple family narrative therapy (MFNT) intervention consisting of parent-child relationships training among Chinese families of children with…
- Conditions
- Dyslexia, Special Education, Special Needs Children
- Trial name
- MFNT-CDYS (NCT05949346)
- Testing
- Multiple Family Narrative Therapy (MFNT), School services for families of children with Dyslexia
- Where
- Hong Kong
- Volunteers
- 123 people
- Sponsor
- Hong Kong Baptist University
Right-to-left Shunt, Migraine
Registry of Right-to-left Shunt Detection by Contrast-enhanced Transcranial Doppler in Chinese Population
The purpose of the study is to evaluate the prevalence and extent of right-to-left shunt (RLS) in Chinese migraineurs, and the morbidity of silent cerebral infarction in migraineurs.
- Conditions
- Right-to-left Shunt, Migraine, Cerebral Infarction
- Trial name
- NCT02425696
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Yingqi Xing
HPV Infection, HPV-Related Carcinoma
To Evaluate the Safety and Immunogenicity of 15-valent HPV Recombinant Vaccine in Chinese People Aged 9-45 Years
To evaluate the safety and Immunogenicity of 15-valent HPV vaccine in 9-45year-old participants.
- Conditions
- HPV Infection, HPV-Related Carcinoma, HPV-Related Intraepithelial Neoplasia, Genital Wart
- Trial name
- NCT06756269
- Testing
- Medium dose for 15-HPV vaccine, High dose for 15-HPV vaccine, 9-HPV vaccine
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Chronic Thromboembolic Pulmonary Hypertension
Change-a Multi-center Chronic Thromboembolic Pulmonary Hypertension （CTEPH） Database in China
The Change Database is a prospective, observational multi-center disease registry, which will collect data on patients with chronic thromboembolic pulmonary hypertension (CTEPH) in China.
- Trial name
- NCT05311072
- Testing
- pulmonary endarterectomy or balloon pulmonary angioplasty
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Childhood Asthma
Experienced Chinese Herbal Formulas on Pediatric Asthma
The purpose of this study is conducting a randomized, single blind, controlled intervention trial to observe the therapeutic effect of experienced chinese herbal formulas based on different stages and different symptoms in…
- Trial name
- NCT02341573
- Testing
- experienced chinese herbal formulas, leukotriene receptor antagonist and bronchial relaxant
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Children's Hospital of Fudan University
Myopia
Trial of Myopia Prevention Using +3D Lenses
The purpose of this study is to assess whether a short-term imposed myopic defocus is effective in preventing the development and progression of juvenile-onset myopia in Chinese children.
- Trial name
- PLS (NCT00627874)
- Testing
- +3D Lenses
- Volunteers
- 1,200 people
- Sponsor
- Sun Yat-sen University
COVID-19; and High Infection Risk of SARS-CoV-2
Tolerability,Safety,Pharmacokinetic Profile and Immunogenicity of a Recombinant Humanized Anti-SARS-CoV-2 Monoclonal Antibody (JS016) for Injection in Chinese Health Subjects
This is a randomized, double-blind, placebo-controlled, phase I clinical study to evaluate the tolerability, safety, pharmacokinetic profile and immunogenicity of JS016 (anti-SARS-CoV-2 monoclonal antibody) injection in Chinese…
- Trial name
- NCT04441918
- Testing
- JS016 (anti-SARS-CoV-2 monoclonal antibody)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Extracorporeal Life Support, Neonate
Chinese Neonatal Extracorporeal Life Support Registry (Chi-NELS)
Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique which provides respiratory and cardiac support to patients with respiratory and/or heart failure.
- Trial name
- NCT05085080
- Sponsor
- Children's Hospital of Fudan University
Hemophilia A, Hemophilia B
Data Registry in Chinese Hemophilia A and B Patients
This is an open-label, prospective, multi-center, patient registry in Chinese Hemophilia A and B patients treated with anti-hemophilic coagulation factor replacement therapy.
- Trial name
- NCT07101224
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China