Clinical trials: Chronic Brain Injury
Spastic Cerebral Palsy
A Physical Therapy Program Targeting Lower Extremity Selective Motor Control in Children With Spastic Cerebral Palsy
The goal of this intervention study is to learn whether a physical therapy exercise camp called will improve leg movement (motor control) and functional ability in children with spastic CP who are between 5 and 18 years.
- Trial name
- NCT07310550
- Testing
- Selective movement of individual lower limb joints, Knee joint strengthening at high velocities, Ankle controlled gaming
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Los Angeles
Cerebral Palsy
Adapted High-Intensity Virtual Reality Exergaming
This study will test the acceptability and benefits of a home-based high-intensity virtual reality exercise program for young people with physical disabilities. The program will last 6 weeks.
- Trial name
- NCT07155213
- Testing
- Virtual reality exergaming
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Alabama at Birmingham
Cerebral Palsy, Scoliosis
Prospective Study of Cerebral Palsy Scoliosis
This is a prospective, multi-centre study that will be looking at two groups of males and females over the course of their operative treatment for cerebral palsy (CP) scoliosis and the years following that treatment.
- Trial name
- NCT00958542
- Testing
- Surgical fusion
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of British Columbia
Cerebral Palsy, Hip Displacement
Characteristics of Children With Cerebral Palsy Who Develops Hip Displacement in Denmark
The aim is to describe the characteristics of children with cerebral palsy in Denmark. Furthermore, we want to focus on status of the children's hips.
- Conditions
- Cerebral Palsy, Hip Displacement, Hip Dislocation, Child
- Trial name
- NCT04398342
- Where
- Denmark
- Volunteers
- 957 people
- Sponsor
- Mette Røn Kristensen
Urinary Incontinence
Prevalence of Incontinence and Risk Factors in Children With Cerebral Palsy
This study evaluates (risk)factors influencing (in)continence in children with and without a brain injury.
- Trial name
- NCT02368262
- Testing
- Questionnaire and micturition and drinking diaries, Uroflowmetry, pelvic floor EMG and bladderscan
- Where
- Belgium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Cerebral Palsy
Upper Extremity Strength in Cerebral Palsy
Rationale: Children with Cerebral Palsy (CP) experience limitations in motor activities and participation in the community, predominantly caused by impairments in muscle function.
- Trial name
- NCT02146989
- Testing
- reproducibility of upper extremity strength measurements
- Where
- 9 sites in Netherlands
- Volunteers
- 370 people
- Sponsor
- Maastricht University Medical Center
Cerebral Palsy, Spastic Diplegia
Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy often experience upper extremity impairments, including reduced coordination, muscle control, and functional hand use, which limit independence in daily activities.
- Trial name
- PNF-TOT-CP (NCT07694804)
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Task-Oriented Training (TOT), Combined Proprioceptive Neuromuscular Facilitation and Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Ibadat International University, Islamabad
Hemiparetic Cerebral Palsy
Telerehabilitation-Based Action Observation Treatment in Children with Hemiparetic Cerebral Palsy
The aim of this study is to evaluate the effectiveness of action observation therapy applied using two different telerehabilitation techniques (synchronous and asynchronous) to children with hemiparetic cerebral palsy.
- Trial name
- NCT05349136
- Testing
- Synchronous telerehabilitation group, Asynchronous telerehabilitation group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Marmara University
Cerebral Palsy
Effects of Horse Riding Simulator With or Without Visual Feedback on Balance and Postural Control
Spastic cerebral palsy is a neurological condition that causes muscle spasticity and motor impairments, greatly impacting a child's ability to maintain balance and control their posture.
- Trial name
- NCT06231147
- Testing
- HORSE RIDING SIMULATOR WITH VISUAL FEEDBACK, HORSE RIDING SIMULATOR WITHOUT VISUAL FEEDBACK
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Children, Adult, Spastic Cerebral Palsy
Full-spectrum Medical Cannabis for Treatment of Spasticity in Patients With Severe Forms of Cerebral Palsy
The proposed study is a double-blind, placebo-controlled, cross over study on 60 children aged 5 to 25 years with severe spasticity related to cerebral palsy (CP), level IV and V with full-spectrum medical cannabis product of…
- Conditions
- Children, Adult, Spastic Cerebral Palsy, Quality of Life, Cannabis
- Trial name
- HemPhar (NCT04634136)
- Testing
- Lab tests, ECG, Cannabinoid Levels
- Where
- 2 sites in Slovenia
- Volunteers
- 55 people
- Sponsor
- University Medical Centre Ljubljana
Dyskinetic Cerebral Palsy Due to Perinatal Hypoxia
Effect of DBS on Quality of Life in Dyskinetic Cerebral Palsy
There are limited therapeutical options for patients with secondary dystonia due to cerebral palsy. Pharmacotherapy is often without effect, or side effects are severe.
- Trial name
- STIM-CP (NCT02097693)
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital of Cologne
Cerebral Palsy
Effects of Lycra Suits in Children With Cerebral Palsy
Lycra garments have recently been used for children with cerebral palsy, with favorable effects on alignment, biomechanics and neuromuscular activity.
- Trial name
- CP (NCT02712021)
- Testing
- Lycra suit and physiotherapy treatment, physiotherapy treatment
- Volunteers
- 10 people
- Sponsor
- Catholic University, Italy
Spastic Cerebral Palsy (sCP)
Rhythmic Stabilization Versus Ball Balancing
Spastic Cerebral Palsy (CP) is the leading cause of upper motor neuron syndrome (UMN) in children. The primary factors contributing to motor behavior disorders in these children are impairments in motor control and muscle…
- Trial name
- NCT06673849
- Testing
- Rhythmic Stabilization, Ball Balancing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Cerebral Palsy
Relationships Between OLST, GMFM and Pedobarographic Values in CP
The primary aim of this study was to investigate the relationship between the One Leg-Standing Test (OLST) and the Gross Motor Function Measurement (GMFM) and stance phase stability during gait in Unilateral Cerebral Palsy (UCP).
- Trial name
- NCT04273204
- Testing
- one leg standing test, gross motor function measurement, pedobarographic measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Child Development Disorders, Preterm Infant
Reliability of Hammersmith Examination in Prediction of Neurological Outcomes (REHAPENO)
In this study workers are trying to test the correlation between Hammersmith Infant Neurological Examination and MRI brain/cranial ultrasound with early prediction of neurological developmental outcome of preterm neonates.
- Conditions
- Child Development Disorders, Preterm Infant, Cerebral Palsy
- Trial name
- REHAPENO (NCT03580252)
- Testing
- Correlation analyses for the outcomes
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Abha International Private Hospital
Bladder Dysfunction, Bowel Dysfunction
Comparison of Transcutaneous Electrical Nerve Stimulation and Manual Therapy in Children With Cerebral Palsy
There are many studies in the literature on healthy children with lower urinary tract dysfunction (LUTD), but there are limited number of studies in children with cerebral palsy (CP) with LUTD.
- Conditions
- Bladder Dysfunction, Bowel Dysfunction, Cerebral Palsy, Neurogenic Bladder
- Trial name
- NCT05351138
- Testing
- TENS, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bahçeşehir University
Cerebral Palsy, Acquired Brain Injury
Proof of Concept of Pediatric and Adolescent EXPLORER V2 Exoskeleton in Children With Neurological and Neuromuscular Disease
The goal of this clinical trial is to analyze the usability and safety of the prototype gait exoskeleton EXPLORE V2 in children with neurological and neuromuscular disease.
- Conditions
- Cerebral Palsy, Acquired Brain Injury, Neuromuscular Diseases in Children
- Trial name
- NCT05914818
- Testing
- EXPLORER V2
- Where
- 5 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- MarsiBionics
Upper Extremity Impairments, Cerebral Palsy (CP)
Obi Medical Robot: Evaluating Effectiveness Related to Usability
This mixed-methods usability study evaluates the effectiveness of the Obi Gen 3 robotic feeding device in meeting user needs among providers, caregivers, and patients.
- Conditions
- Upper Extremity Impairments, Cerebral Palsy (CP), ALS - Amyotrophic Lateral Sclerosis, Rett Syndrome
- Trial name
- NCT07151950
- Testing
- One-week trial of Obi Medical device, which provides robotic assistance with feeding to persons with upper extremity impairments who are unable to self-feed in the traditional manner using utensils
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Desin LLC
Cerebral Palsy Infantile, Neuromuscular Diseases in Children
Virtual Reality Impact on Powered Mobility: a Feasibility Study
This study explores the potential of Virtual Reality (VR) technology to enhance powered wheelchair (PW) training for children diagnosed with Cerebral Palsy (CP) and neuromuscular diseases (NMDs).
- Trial name
- VR-PMP (NCT06586125)
- Testing
- Powered Mobility Training
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Azienda Usl di Bologna
Cerebral Palsy
Neurocytotron on Cerebral Palsy
This is a randomized, double-blinded, two-arm, placebo-controlled clinical study. The enrollment will be randomized 1:1 to Neurocytotron treatment or mock treatment (placebo).
- Trial name
- NCT03743623
- Testing
- Neurocytotron
- Where
- Mexico
- Volunteers
- 53 people
- Sponsor
- Neurocytonix, Inc.
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