Clinical trials: Chronic Consciousness Disorders
Disorders of Consciousness
mindBEAGLE: Unlocking Functional Communication for Patients With Disorders of Consciousness
The goal of this clinical trial is to test how effective the mindBEAGLE device is in allowing people who are unconscious (due to a brain injury or other condition) to communicate using brain waves to answer Yes/No questions.
- Trial name
- NCT06426602
- Testing
- mindBEAGLE daily device use
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Amy Wagner
Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients
Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury
This prospective observational study evaluates the safety profile and patient-reported outcomes associated with MUSE (Multilineage-differentiating Stress-Enduring) stem cell therapy in individuals aged 6 to 75 with chronic…
- Conditions
- Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients, Traumatic Brain Injury (TBI); Concussion, Initial Encounter, Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter
- Trial name
- MUSE-TBI-OBS (NCT07326059)
- Testing
- MUSE Stem Cell Therapy
- Where
- 2 sites in United States, Mexico
- Volunteers
- 10 people
- Sponsor
- Healing Hope International
Cerebral Palsy
Conscious Sedation With Nitrous Oxide in Control of Stress During Dental Care for Individuals With Cerebral Palsy
Cerebral Palsy induces oral alterations that impact on oral health, requiring dental treatment. The objective of this study was to evaluate the use of conscious sedation with nitrous oxide (N2O) in the control of stress during…
- Trial name
- NCT02322983
- Testing
- Control of Stress
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Universidade Cruzeiro do Sul
Syncope, Arrest
Urgent Medical and Surgical Conditions During Flights
The aim of this study is to evaluate the incidence and status of urgent medical conditions. After defining the urgent situations, the investigators will evaluate the adequacy of the standard medical kits and trainings.
- Conditions
- Syncope, Arrest, Vertigo, Pain
- Trial name
- NCT02457455
- Where
- Turkey (Türkiye)
- Volunteers
- 1,312 people
- Sponsor
- Antalya Training and Research Hospital
Minimally Conscious State, Vegetative State
Validation of the Chinese Version of the SECONDs
The aim of this study was to translate the SECONDs from English into Chinese and determine the validity of this Chinese version
- Trial name
- NCT04687553
- Testing
- Simplified Evaluation of CONsciousness Disorders (SECONDs)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hangzhou Normal University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
We and others have shown that many younger patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have orthostatic intolerance (OI), i.e., they can't tolerate prolonged standing.
- Conditions
- Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Systemic Exertion Intolerance Disease (SEID), Postural Tachycardia Syndrome (POTS)
- Trial name
- NCT02854683
- Testing
- Normal Saline, Oral Rehydration Solution
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Vegetative State, Minimally Conscious State
Thalamic Stimulation of Patients in Vegetative or Minimally Conscious State
Rationale. The investigators hypothesize that bilateral electrical central thalamic stimulation of patients in Vegetative State and Minimally Conscious State from at least 6 months could improve the level of responsiveness. Aims.
- Trial name
- CATS\ (NCT01027572)
- Testing
- Implantable neurostimulation system (Medtronic)
- Where
- 3 sites in Italy
- Volunteers
- 5 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Emphysema or COPD
Chartis Collateral Ventilation Measurement: Conscious Sedation Versus General Anesthesia
Rationale: The Chartis® ( Pulmonx, CA, USA) measurement system is a tool to assess interlobar collateral ventilation during bronchoscopy.
- Trial name
- NCT03205826
- Testing
- Type of sedation used
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Vasovagal Syncope, Postural Tachycardia Syndrome
Hypnosis in Autonomic Function
This study will investigate the relationship between susceptibility to hypnosis and regulation of the autonomic nervous system (nerves that control involuntary body functions, such as heart rate and sweating).
- Conditions
- Vasovagal Syncope, Postural Tachycardia Syndrome, Hypnosis
- Trial name
- NCT00061009
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Vegetative State, Minimally Conscious State
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- tDCS in DOC (NCT01673126)
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University of Liege
Disorder of Consciousness
Proteomics for Chronic Disorder of Consciousness
Following severe traumatic brain injury, patients may remain unconscious for many years. It is the first proteomic analysis comparing differentially expressed proteins between patients with chronic disorder of consciousness and…
- Trial name
- NCT03611166
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Neurocardiogenic Syncope
Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance
This study will examine the effectiveness of the drug propranolol in preventing fainting in patients with sympathoadrenal imbalance (SAI).
- Trial name
- NCT00060866
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)