Clinical trials: Chronic Headaches
Hydrocephalus
Assessment of CSF Shunt Flow and Headaches With a Thermal Measurement Device
This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a study subject during headache and non-headache periods.
- Trial name
- NCT06996600
- Testing
- wireless thermal anisotropy measurement device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Rhaeos, Inc.
Migraine, Migraine in Adolescence
Mindfulness-Based Intervention for Adolescents With Chronic Migraine
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on…
- Trial name
- NCT06414109
- Testing
- BREATHE-Migraine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Headaches Chronic
Feasibility and Effectiveness of Home-behavioral Program for Adolescents With Migraine
Chronic Migraine and Migraine without aura at high frequency are disabling conditions also in adolescence age (2% of adolescents report chronic migraine) Common pharmacological treatments are often inadequate.
- Trial name
- Be-Home-Kids (NCT04604977)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine
A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine
The purpose of this study is to learn about the effect of a study medicine called rimegepant in adolescents who have frequent migraine attacks. Rimegepant is a tablet that disintegrates when you put it on or under your tongue.
- Trial name
- NCT06616194
- Testing
- Rimegepant
- Where
- 102 sites in United States, Canada and 10 more
- Volunteers
- 636 people
- Sponsor
- Pfizer
Chronic Pain, Abdominal Pain
Problem Solving Skills Training For Parent Caregivers of Youth With Chronic Pain
The purpose of this study is to evaluate the feasibility and efficacy of problem-solving skills training (PSST) to reduce distress and increase coping abilities among parents of youth with chronic pain.
- Conditions
- Chronic Pain, Abdominal Pain, Headache
- Trial name
- NCT01496378
- Testing
- Problem-Solving Skills Training
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Seattle Children's Hospital
Headache Disorders, Secondary, Post-Dural Puncture Headache
Association Between Chronic Headache and Back Pain With Childbirth
This study uses a single questionnaire to evaluate two separate primary outcomes: 1. To identify association between chronic headache in women who have given birth to children as compared to a control group of women who have…
- Conditions
- Headache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain
- Trial name
- NCT04091321
- Where
- United States
- Volunteers
- 1,112 people
- Sponsor
- Stanford University
Chronic Migraine
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine
The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age.
- Trial name
- REBUILD-2 (NCT04616326)
- Testing
- Galcanezumab
- Where
- 88 sites in United States, Denmark and 9 more
- Volunteers
- 312 people
- Sponsor
- Eli Lilly and Company
Tension Type Headache, Migraine
Yoga for Chronic Headache in Adolescents
A randomized controlled trial to investigate the efficacy of yoga on tension type headache and / or migraine in adolescents between 12 and 16 years, consisting of a four group design which includes an 12 week yoga course and a…
- Trial name
- NCT02721849
- Testing
- Yoga for adolescents, Yoga for parents
- Where
- 2 sites in Germany
- Volunteers
- 45 people
- Sponsor
- Universität Duisburg-Essen
Chronic Headache, Migraine Headache
A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Headache
The purpose of this study is to preliminarily establish the extent to which a brief aromatherapy intervention incrementally improves subjective and objective indicators of discomfort (pain, anxiety, and heart rate variability)…
- Conditions
- Chronic Headache, Migraine Headache, Headache
- Trial name
- NCT02440997
- Testing
- aromatherapy, foot bath
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Children's Mercy Hospital Kansas City
Chronic Daily Headache
Atkins Diet for Difficult-to-Control Headaches in Teenagers
This is a 3-month pilot study of 10 adolescents with chronic daily headache. Teens will be placed on a modified Atkins diet and followed with 2 subsequent visits to assess for headache improvement.
- Trial name
- NCT00181064
- Testing
- Modified Atkins diet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Emotions, Corticosteroids
Mapping Emotional Dynamics During Corticosteroid Treatment
Rationale: Synthetic glucocorticoids can result in neuropsychiatric adverse effects in a minority of patients. Although, not all patients experience severe adverse effects, more subtle emotional disturbances are often…
- Trial name
- NCT05391295
- Testing
- Short daily questionnaire
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Leiden University Medical Center
Chronic Migraine, Headache, Chronic Migraine
Rate , Predictors and Outcome of Chronic Migraine
Nowadays, headache has been considered as one of the top global disabling medical conditions.1 Migraine is an important type of headache, and one of the chronic multifaceted neuro-inflammatory disorders.2 It is characterized by…
- Trial name
- NCT05079659
- Where
- Egypt
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Headache
Chiropractic Treatment for Headache Among Children Aged 7-14
The primary aim of the study is to assess the effectiveness of chiropractic manipulation treatment versus placebo treatment in children suffering from headache for more than six months.
- Trial name
- NCT02684916
- Testing
- Chiropractic treatment
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Nordic Institute of Chiropractic and Clinical Biomechanics
Chronic Pain, Headache
Web-based CBT for Children With Chronic Pain
The purpose of this study is to develop and evaluate the feasibility and effectiveness of a web-based (i.e., internet) treatment approach for providing psychological treatment to reduce pain and improve functioning in children…
- Conditions
- Chronic Pain, Headache, Abdominal Pain
- Trial name
- NCT00853138
- Testing
- cognitive-behavioral therapy
- Volunteers
- 48 people
- Sponsor
- Seattle Children's Hospital
Headache, Headache Disorders
Mind Body Balance for Pediatric Migraine
This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT04715685
- Testing
- 40 minute session, 20 minute session, home practice e-health
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Pain
The Turkish Version of Functional Disability Inventory
The goal of this study is to determine the validity and reliability of the Turkish version of the Functional Disability Inventory (FDI), which assesses functional disability in daily life, school, and home activities of children…
- Trial name
- NCT05422456
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine Disorders
Chronic Migraine Epidemiology and Outcomes Study
This is a population internet-based study to characterize migraine clinical course and impact on family.
- Trial name
- NCT01648530
- Testing
- No Treatment
- Volunteers
- 16,789 people
- Sponsor
- Allergan
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Pediatric, Headache
A Study of Family-based Cognitive-behavioral Therapy for Chronic Pediatric Headache and Anxiety
The primary aim of this proposal is to refine the intervention under investigation (i.e., family-based CBT) and evaluate the feasibility and acceptability of the intervention and methods (e.g., recruitment, assessments).
- Conditions
- Pediatric, Headache, Anxiety
- Trial name
- NCT01182051
- Testing
- CBT or relaxation training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University