Clinical trials: Chronic Obstructive Pulmonary Disease Exacerbation
Asthma Acute, Asthma in Children
User-Friendly Spirometer and Mobile App for Self-Management and Home Monitoring of Asthma Patients
The primary goal of this proposal is to use an in-home, smartphone-enabled, hand-held spirometer to determine the FEV1% predicted ranges that predict the Yellow Zone threshold.
- Conditions
- Asthma Acute, Asthma in Children, Asthma Chronic, Asthma Attack
- Trial name
- NCT03642418
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Asthma, Reactive Airway Disease
Comparison of Oral Dexamethasone Doses in Asthma Exacerbation
Hypothesis: A 2-day course of oral dexamethasone is the superior option for the resolution of symptoms and prevention of relapse in the emergency department (ED) management of mild-moderate asthma exacerbations.
- Trial name
- NCT00942201
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Rady Children's Hospital, San Diego
COPD Exacerbation, COPD
Impulse Oscillometry in COPD Exacerbation
This study aimed to evaluate small airway function during ECOPD and recovery periods using IOS. In this prospective single-center study, patients with ECOPD underwent evaluation of their pulmonary functions using IOS and…
- Trial name
- NCT07185581
- Testing
- Impulse Oscillometry
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Deniz Bilici
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Does Positive Expiratory Pressure Mask Therapy Improve Recovery From Acute Exacerbations of Chronic Obstructive Pulmonary Disease?
This study aims to identify whether the addition of positive expiratory pressure (PEP) mask therapy to standard medical care improves clinically important outcomes in individuals with acute exacerbations of chronic obstructive…
- Trial name
- NCT01101282
- Testing
- Positive expiratory pressure (PEP) mask therapy
- Where
- 2 sites in Australia
- Volunteers
- 92 people
- Sponsor
- La Trobe University
COPD Exacerbation
Early Assisted Discharge for COPD Exacerbations With Telemonitoring.
To determine if an early assisted discharge program for acute exacerbations of COPD (AECOPD), with telemonitoring and telephone control, is equally effective and more efficient in terms of use of health care resources, that a…
- Trial name
- NCT01951261
- Testing
- Telemonitoring and telephone control
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Dr. López Viña
Acute Exacerbation of COPD
Non Invasive Ventilation With NAVA vs ASV for AECOPD
Non invasive ventilation is the standard of care in managing patients with exacerbation of chronic obstructive pulmonary disease.
- Trial name
- NCT04414891
- Testing
- Non invasive ventilation
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
COPD - Chronic Obstructive Pulmonary Disease, Muscle Atrophy
Progressive Resistance Training of the Extensor Muscle of the Thigh in COPD-patients Hospitalized With an Exacerbation
We want to test the hypothesis, that resistance training by the use of weigth cuffs on the angle can prevent loss or improve the strength of the quadriceps muscle in COPD patients admitted to hospital due to an exacerbation.
- Trial name
- NCT01812460
- Testing
- Intervention-training-group
- Where
- Denmark
- Sponsor
- Frederikssunds Hospital, Denmark
Chronic Obstructive Pulmonary Disease
A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD)
A real world study to determine the effectiveness of a patient support service to aid COPD patients in their self management.
- Trial name
- Me&MyCOPD (NCT02300090)
- Testing
- Test Group, Control Group
- Where
- 23 sites in United Kingdom
- Volunteers
- 161 people
- Sponsor
- AstraZeneca
Asthma
Assessment of PFT, Safety, and PK of Zileuton Injection in Asthma Patients
A single intravenous injection of zileuton (150 or 300 mg) will be administered to patients with stable asthma. The goals will be to determine if zileuton i.v.
- Trial name
- NCT00534625
- Testing
- zileuton
- Volunteers
- 36 people
- Sponsor
- Critical Therapeutics
Chronic Obstructive Pulmonary Disease, Exacerbation Copd
15-year Mortality After Hospitalization for Exacerbation of Chronic Obstructive Pulmonary Disease
The investigators examine the 15-year mortality after an admission for an exacerbation of Chronic Obstructive Pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Exacerbation Copd, Mortality
- Trial name
- MORTCOP (NCT02972775)
- Testing
- no interventions. observational study
- Where
- Netherlands
- Volunteers
- 845 people
- Sponsor
- Zuyderland Medisch Centrum
COPD, Muscle Weakness
Feasibility of Strength Training in Patients Hospitalized Due to COPD
To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD
- Trial name
- NCT01981200
- Testing
- Resistance training in AECOPD
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Frederikssunds Hospital, Denmark
Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Effectiveness and Feasibility of Delivering an Education Program to Patients With an Acute Exacerbation of COPD
The purpose of this study is to determine if it is effective and feasible to provide a chronic obstructive pulmonary disease (COPD) education program to patients admitted with an acute exacerbation of COPD.
- Trial name
- NCT02321215
- Testing
- Introductory Disease Education
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- West Park Healthcare Centre
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Decision-making and Optimization of Ventilatory Support for AECOPD Patients
The goal of this retrospective observational study is to learn about how respiratory support is selected and adjusted in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
- Trial name
- OPTIVENT-COPD (NCT07508943)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sir Run Run Shaw Hospital
Pulmonary Disease, Chronic Obstructive
European Quality of Care Pathways Study on Chronic Obstructive Pulmonary Disease (COPD)
Care pathways, a complex intervention to (re)organise, standardize and evaluate care processes, are used worldwide and in different kinds of settings. Although their international use, the impact is unclear.
- Trial name
- EQCP-COPD (NCT00962468)
- Testing
- COPD evidence based care pathway
- Volunteers
- 342 people
- Sponsor
- European Pathway Association
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Chronic Obstructive Airways Disease Exacerbated
Examining the Effectiveness of Single-Limb Exercise Training for COPD Patients During Exacerbation Periods
Resistance exercise applications during acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are employed to enhance functional capacity and prevent muscle atrophy by increasing muscle strength.
- Trial name
- NCT07348003
- Testing
- Single Limb Exercise Training, Routine Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Alper Kemal Gürbüz
Chronic Obstructive Pulmonary Disease
Eosinophilic Cationic Protein as a Biomarker in Diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is a type of obstructive lung disease characterized by long-term breathing problems and poor airflow.
- Trial name
- NCT04008017
- Testing
- Eosinophilic Cationic Protein biomarker
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Airways Disease
Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation
Background: In chronic obstructive pulmonary disease, the prognosis for patients who have survived an episode of acute hypercapnic respiratory failure due to an exacerbation is poor.
- Conditions
- Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Airways Disease, Chronic Hypercapnic Respiratory Failure
- Trial name
- NCT01513655
- Testing
- LTNIV
- Where
- 4 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Study to Evaluate the Clinical Value and Safety of Xiyanping Injection in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(COPD) Based on Real-world Clinical Data
The primary objective is to evaluate the effect of Xiyanping injection on the treatment course of intravenous antibiotics for acute exacerbation of chronic obstructive pulmonary disease based on real-world clinical data, and to…
- Trial name
- XYP-202401 (NCT06754865)
- Testing
- Xiyanping injection+ antibiotic, Antibiotic
- Volunteers
- 1,140 people
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
COPD Exacerbation
Oral Prednisolone in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)
Evaluation of systematic administration of oral prednisolone (1mg/Kg/day) as an add on therapy in Chronic Obstructive Pulmonary Disease (COPD) patients admitted to intensive care unit (ICU) for severe exacerbation of COPD.
- Trial name
- NCT01353235
- Testing
- Prednisolone, usual care
- Where
- Tunisia
- Volunteers
- 317 people
- Sponsor
- Fekri Abroug