Clinical trials: Chronic Otitis Media
Chronic Otitis Infections in pédiatric Patients
Efficacy of KNT® (KINETUBE) in Recurrent Chronic Otitis Media in Children
Otitis media are the consequence of bacterial infection. They are characterized by middle ear inflammations with a collection of fluid behind the eardrum.
- Trial name
- KINETUBE (NCT02038400)
- Testing
- KINETUBE medical Device, insertion of tympanic ventilation tubes (tympanostomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Otitis Media, Otitis Media Effusion
Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media
The goal of this clinical trial is to learn whether osteopathic manipulative treatment, or OMT, can reduce the need for tympanostomy tube surgery in children with recurrent or chronic otitis media who have been referred to an…
- Conditions
- Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children
- Trial name
- NCT07639775
- Testing
- Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sarah Vidal
Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps
The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear.
- Trial name
- NCT03975842
- Testing
- Sinonasal and otologic evaluation
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Chronic Otitis Media
Effectiveness of Sulfamethoxazole-trimethoprim in the Treatment of Chronic Otitis Media
Chronic suppurative otitis media is one of the most common chronic infections in children worldwide. Symptoms include otorrhea, otalgia and hearing loss.
- Trial name
- NCT00189098
- Testing
- Sulfamethoxazole-trimethoprim
- Where
- Netherlands
- Volunteers
- 101 people
- Sponsor
- UMC Utrecht
Otitis Media, Otitis Media Chronic
SWIR Otoscopy Study
The aim of this study is to provide preliminary data to support future studies to demonstrate that the short wave infrared (SWIR) otoscope is a better diagnostic tool than a white light otoscope for diagnosing middle ear…
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion
- Trial name
- NCT06944795
- Testing
- SWIR device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Chronic Otitis Media, Tubotympanic Disease
A Comparative Study of the Outcomes of 2 Surgical Procedures for Safe Type of Chronic Otitis Media
Mastoidotympanoplasty is a recognised surgery that is performed for chronic otitis media. But whether mastoidectomy in addition to tympanoplasty is really necessary in each and every case of quiescent chronic otitis media still…
- Trial name
- NCT00271778
- Testing
- mastoidotympanoplasty and tympanoplasty
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Karnataka Institute of Medical Sciences
Tympanic Membrane Perforation, Conductive Hearing Loss
Outcomes of Cartilage Tympanoplasty in Children
This study evaluates the anatomical and hearing outcomes of cartilage tympanoplasty in pediatric patients with chronic tympanic membrane perforations.
- Conditions
- Tympanic Membrane Perforation, Conductive Hearing Loss, Chronic Otitis Media
- Trial name
- NCT07866222
- Testing
- Cartilage Tympanoplasty
- Volunteers
- 35 people
- Sponsor
- Assiut University
Chronic Otitis Media
Tegmen Defect Management During Mastoidectomy
In this study, we aimed to discuss our clinical experience on the management of the tegmen defects which were revealed during the mastoidectomy surgeries.
- Trial name
- NCT04374266
- Testing
- physical examination, and computerized tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medeniyet University
Otitis Media With Effusion, Healthy
The URT and Middle Ear Microbiota in Health and During Chronic OME
This study analyses which bacteria are present in the middle ear space and adjacent upper respiratory tract niches in healthy people and in patients suffering from chronic otitis media with effusion (OME; glue ear).
- Trial name
- NCT03109496
- Testing
- Collection of body fluids/swabs
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Antwerp
Chronic Otitis Media
Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement
This is a study to compare intranasal dexmedetomidine to intranasal fentanyl following anesthesia induction in patients undergoing myringotomy and placement of pressure equalization (PE) tubes in providing analgesia and smoothing…
- Trial name
- NCT01188551
- Testing
- Dexmedetomidine, Fentanyl, Midazolam
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nationwide Children's Hospital
Otitis Media, Otitis Media Chronic
CLIKX® Tympanostomy Tube Delivery System for the Placement of Tympanostomy Tubes
This study looks at the safety and performance of the CLiKX device. The device is used to place ear tubes (also called ventilation tubes) in children and adults.
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion, Otitis Media Recurrent
- Trial name
- NCT07625657
- Testing
- CLiKX® Tympanostomy Tube Delivery System
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- ClinQure, Inc.
Chronic Serous Otitis Media, Simple or Unspecified
Prevalence of Mucosal Biofilm Formations in Adenoidectomy Specimens
Rationale: Bacterial biofilms are defined as an assemblage of bacterial cells enclosed in a self-produced glycocalyx matrix. Adherence on surfaces, and resistance to both antibiotic treatments and host defenses are ones of the…
- Trial name
- BOLERO (NCT01022944)
- Testing
- With chronic middle ear effusion, Without chronic middle ear effusion
- Where
- France
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Otitis Media
The Effects of Ventilation Tubes - The SIUTIT Trial
The prevalence of otitis media among Greenlandic children is one of the highest in the world and twenty per cent of schoolchildren have impaired hearing in the frequencies for normal speech.
- Trial name
- SIUTIT (NCT02490332)
- Testing
- Ventilation tube treatment
- Where
- 6 sites in Greenland
- Volunteers
- 31 people
- Sponsor
- Zealand University Hospital
Otitis Media With Effusion, Laryngopharyngeal Reflux
Three Methods Used in the Diagnosis of EER in Children With OME
Detection of extraesophageal reflux (EER) in children with chronic otitis media with effusion (OME) using three different diagnostic methods and selection of the group of patients with severe EER who could potentially benefit…
- Trial name
- NCT02183961
- Testing
- Restech, Peptest, Detection of pepsin in adenoid specimen
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- University Hospital Ostrava
Chronic Suppurative Otitis Media, Mastoid Cavity
Study the Impact of the Mastoid and Middle Ear Volume on the Success of Type 1 Tympanoplasty in Pediatric Age, With Comparing Using Cartilage and Fascial Grafts Through This, Strength the Hypothesis of That Total Tympanometry Volume Correlates With Ventilated Mastoid Air Cells Volume on CT Scans
The goal of this observational study is to know the impact of the mastoid and middle ear volume on the success of type 1 tympanoplasty in pediatric age, with a closer view on the comparison of using cartilage and fascial grafts…
- Conditions
- Chronic Suppurative Otitis Media, Mastoid Cavity, Pneumatization, Tympanoplasty
- Trial name
- NCT07806461
- Testing
- tympanoplasty type 1, Audiological Evaluation, HRCT scan temporal bone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Chronic Otitis Media, Cholesteatoma
A Study of the Clinicopathologic Behaviour of the Different Types of Unsafe Chronic Otitis Media
The purpose of the study is to study the clinicopathologic behaviour of the 3 dangerous types of chronic otitis media that are prone for complications.
- Trial name
- NCT00270660
- Testing
- biopsy, audiometry, ET function test, ear swab culture, DNE
- Where
- India
- Volunteers
- 192 people
- Sponsor
- Karnataka Institute of Medical Sciences
Otitis Media With Effusion
A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion
This study is being done to see if reflux of stomach fluid might be a cause of chronic fluid in the ears. Our hypothesis is that treatment with an anti-reflux medication (lansoprazole) will increase the rate of resolution of…
- Trial name
- NCT00546117
- Testing
- lansoprazole
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Vertigo Labyrinthine
Evaluation of Vestibular Function in Patients With C.S.O.M: Safe Type
To evaluate the function of vestibular system in patients with chronic suppurative otitis media safe type.
- Trial name
- NCT04791930
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Suppurative Otitis Media, Hearing Impairment
Prevalence and Associations of Paediatric Chronic Suppurative Otitis Media and Hearing Impairment in Rural Malawi
This community-based cross-sectional survey will estimate the frequency and risk factors of Chronic Suppurative Otitis Media and Hearing Impairment in Children ages 4-6 years in the Chikwawa District.
- Trial name
- NCT02779907
- Testing
- No Intervention
- Where
- Malawi
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Chronic Otitis Media
Validity of the French Version of the Quality of Life Questionnaire COMQ12-FR
The World Health Organization estimates that chronic otitis media could reach between 65 and 350 million people worldwide and thus be an important cause of medical consultation and prescription drugs.
- Trial name
- COMQ12-FR (NCT04423952)
- Testing
- COMQ-12 questionnaire
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris