Clinical trials: Chronic Post Operative Pain
Chronic Pain, Postoperative, Quality of Life
Quality of Life and Pain After Appendectomy in Children
Acute appendicitis is one of the most common emergency general surgical conditions worldwide and represents the leading cause of emergency abdominal surgery in children.
- Conditions
- Chronic Pain, Postoperative, Quality of Life, Functional Ability, Appendectomy
- Trial name
- CAPA-Peds (NCT07629362)
- Where
- Turkey (Türkiye)
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Chronic, Infection
Pulpectomy of Primary Molars With Rotary Instrumentation Versus Manual Instrumentation
One of the major concerns in pediatric dentistry is premature loss of necrotic primary teeth which may cause a deleterious effect on the growth of the facial skeletal complex.
- Trial name
- NCT03964766
- Testing
- Rotary instrumentation, Hand instrumentation
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Persistent Postoperative Pain
Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children
Persistent postoperative pain is a substantial pain (scores 4-10 using a 0-10 numeric scale) that develops 3 months after surgery. Persistent postoperative pain can be a problem even in ambulatory surgery.
- Trial name
- AWA3PASIC (NCT06271174)
- Testing
- Carbocaine, Profofol and/or Suxaméthonium and/or Sévoflurane
- Where
- France
- Volunteers
- 208 people
- Sponsor
- Nantes University Hospital
Pain, Chronic, Pain, Chronic Post-Surgical
iCanCope With Post-Operative Pain (iCanCope PostOp)
There are few applications available in the community to help teenagers manage pain after surgery. The focus of this study is to better understand the pain experience of children after having surgery and to design a Smartphone…
- Trial name
- NCT05382962
- Testing
- iCanCope Post Op Application
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Quality of Life, Living-donor Liver Transplantation
The Effect of Individualised Pain Education on Chronic Postoperative Pain Development and Quality of Life in Living Liver Donors
Chronic postoperative pain is defined as pain that is a continuation of acute pain or develops after a pain-free period, is localised to the surgical site, affects quality of life, and persists for at least 3 months after surgery…
- Conditions
- Quality of Life, Living-donor Liver Transplantation, Chronic Post Operative Pain, Pain Management
- Trial name
- NCT06609772
- Testing
- Individualised Pain Education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Nazlican Bagci
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Opioid Use Disorder, Pain, Chronic
Adolescent Outcomes of Post-operative Opioid EXposure
The goal of this observational study is to examine the factors associated with the transition from medical exposure to opioids with "signposts" of future opioid use disorder among adolescent surgical patients.
- Trial name
- APEX (NCT06350409)
- Where
- 5 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Sharon Levy
Pain, Pain, Postoperative
Prediction and Characterization of Acute and Chronic Postoperative Pain
Despite enormous progress insufficient postoperative pain management remains a frequent problem in the early postoperative phase after surgery.
- Conditions
- Pain, Pain, Postoperative, Funnel Chest
- Trial name
- NCT01308385
- Testing
- Conditioned pain modulation
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Postoperative Chronic Pain
Postoperative Chronic Pain in Children Aged 8 to 17
The objective of this study is to assess the incidence of chronic postoperative pain in pediatric patients aged 8 to 17 years following surgical procedures.
- Trial name
- NCT07120399
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people
- Sponsor
- Kocaeli University
Postoperative Pain
Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis
randomized clinical trial which Evaluate thr Post-operative Pain Following Platelet Rich Plasma (PRP) Revascularization versus Conventional Endodontic Treatment of Non-vital Mature Mandibular Molars with Chronic Peri-apical…
- Trial name
- NCT03350841
- Testing
- Platelet rich plasma PRP, root canal treatment
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Epidemiology Study and Risk Factor Analysis on Chronic Post-surgical Pain After Video-assisted Thoracic Surgery
This study is a nationwide multi-center study to investigate the incidence and risk factors of chronic post-surgical pain (CPSP) after receiving video-assisted thoracic surgery (VATS).
- Trial name
- NCT05473728
- Where
- China
- Volunteers
- 886 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Chronic Tonsillitis, Tonsillectomy
Comparison of Cold Dissection Technique and Needle Monopolar Electrocautery Tonsillectomy
Patients 13-years-or older who undergo tonsillectomy operation (without another additional surgery) will be enrolled in the study.
- Conditions
- Chronic Tonsillitis, Tonsillectomy, Tonsillar Hypertrophy
- Trial name
- TONSIL (NCT02818647)
- Testing
- Tonsillectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Chronic Postsurgical Pain
CSF Single-cell Sequencing and Proteomics of Chronic Postsurgical Pain in Patients With Lower Limb Fractures
The purpose of this study is to assess the proteomics and transcriptomic differences between pain-free control subjects and patients with chronic postoperative pain through single-cell sequencing technology.
- Trial name
- NCT06126289
- Volunteers
- 20 people
- Sponsor
- Xuzhou Central Hospital
Chronic Post-surgical Pain
Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults
The current project will (1) enhance our understanding of the neurobiology of chronic post-surgical pain (CPSP); (2) provide a metric to follow patients with CPSP in the clinic; (3) provide a metric for those who will chronify…
- Trial name
- NCT05304286
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Massachusetts General Hospital
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Postoperative Pain, Cerebral Palsy
Postoperative Pain in Children With Cerebral Palsy After Pelvic and Femoral Osteotomies
This study is a comparison of postoperative pain in children with cerebral palsy after surgery on the hip or femur. One group is treated with p.o.
- Trial name
- NCT00964639
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Pain, Postoperative, Chronic Pain Syndrome
Prevalence of Pain in the Departments of Surgery and Oncoematology of a Children's Hospital
Six years after, the authors will conduct the same analysis to check if there have been any improvements in the management of analgesic therapy after the measures taken according to the results of the previous study conducted in…
- Trial name
- NCT04209764
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- Giuliano Marchetti
Tonsillectomy, Tonsillitis Chronic
BiZact Tonsillectomy in the Pediatric Population
This study has been designed to evaluate how effective the Bizact tonsillectomy device is in reducing operating time and complications that occur after surgery.
- Conditions
- Tonsillectomy, Tonsillitis Chronic, Hemorrhage, Postoperative Pain
- Trial name
- NCT04725305
- Testing
- BiZact, Standard of care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Baylor College of Medicine
Chronic Pain
Incidence and Associated Factors of Persistent Postoperative Incision Scar Pain Following C/s in Mulago Hospital
prospective cohort study of women who underwent caesarean section in mulago hospital. followed up for 2 months and assessed for development of persistent post operative pain at the incision site and its effect on quality of life.
- Trial name
- PPOPinC/S (NCT03269188)
- Volunteers
- 277 people
- Sponsor
- Makerere University