Clinical trials: Chronic Ulcers
Dry Eyes, Sjogren's Disease With Dry Eyes
Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood
To investigate if fresh finger prick autologous blood (FAB) instead of serum from venesection, is a safe and effective treatment for dry eyes and corneal ulcers/ epithelial defects.
- Conditions
- Dry Eyes, Sjogren's Disease With Dry Eyes, Persistent Corneal Epithelial Defects, Chronic Corneal Ulcers
- Trial name
- FAB (NCT02153515)
- Testing
- Your own ( autologous) finger prick of blood produced with a diabetic lancet
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Bedford Hospital NHS Trust
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Ulcerative Colitis, Phosphatidylcholine
Retarded Phosphatidylcholine in Steroid-Dependent Chronic Active Ulcerative Colitis
The purpose of this study is to evaluate if retarded release phosphatidylcholine is an effective alternative to steroid dependent or -refractory course in chronic active ulcerative colitis.
- Trial name
- NCT00259545
- Testing
- Retarded Release Phosphatidylcholine (rPC)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heidelberg University
Healthy, Skin Ulcer
Pathophysiology of Chronic Wounds
This study will compare blood from healthy volunteers and with wound fluid and tissue samples from patients with acute and chronic wounds enrolled in other NIH studies.
- Trial name
- NCT00006437
- Where
- United States
- Volunteers
- 999 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Gastroesophageal Reflux Disease (GERD), Peptic Ulcers
Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)
Gastroesophageal reflux disease (GERD) is a medical condition affecting the stomach and esophagus. GERD might occur when the lower esophageal sphincter does not close properly and stomach contents leaks back (refluxes) into the…
- Trial name
- NCT00261300
- Testing
- Pantoprazole
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Takeda
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
Chinese Spondyloarthritis Inception Cohort (CESPIC)
The Chinese Spondyloarthritis Inception cohort (CESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in China on patients with early SpA including ankylosing spondylitis (AS, also known as…
- Conditions
- Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA), Axial Psoriatic Arthritis (axPsA), Acute Anterior Uveitis (AAU)
- Trial name
- CESPIC (NCT05960864)
- Testing
- Celecoxib
- Volunteers
- 1,000 people
- Sponsor
- Southwest Hospital, China
Platelet-Derived Growth Factor, Diabetic Foot
Evaluation of the Safety Follow-up of Becaplermin or Placebo Gel Following Treatment of Chronic, Full Thickness Diabetic Ulcers
The purpose of this study is to retrospectively evaluate the safety of sterile becaplermin gel compared with sterile placebo gel treatment 12 months or more after the last dose was administered in 1 of 2 double-blind trials…
- Conditions
- Platelet-Derived Growth Factor, Diabetic Foot, Neoplasms
- Trial name
- NCT00740922
- Volunteers
- 563 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Epidermolysis Bullosa, Chronic Skin Ulcer
Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients
To evaluate the effect of human amniotic membrane as a weekly dressing on chronic wounds in Epidermolysis Bullosa (EB) patients.
- Trial name
- NCT03942250
- Testing
- REGE pro dressing
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Egyptian Atomic Energy Authority
Inflammatory Bowel Disease, Crohn Disease
Improving OutcoMes in the Pediatric to Adult Care Transition in Inflammatory Bowel Disease
The transition from pediatric to adult IBD care can be stressful and wrought with challenges including access to care and establishment of new physician-patient relationships.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Colitis, Ulcerative
- Trial name
- IMPACT-IBD (NCT02085083)
- Testing
- Telephone and email correspondence with an Inflammatory Bowel Disease Nurse, Minimal Intervention Arm
- Where
- 3 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Mount Sinai Hospital, Canada
Inflammatory Bowel Disease, Ulcerative Colitis
Efficacy of Energy Therapy in the Management of Chronic Pain Medical Condition in Children and Adolescents.
Paediatric and adolescent patients with chronic pain associated with their medical condition will be invited to participate in this study.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn Disease, Chronic Pancreatitis
- Trial name
- ET&CP (NCT05394272)
- Testing
- Energy Therapy - Pranic Healing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College Hospital NHS Trust
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Chronic Gastritis Caused by Helicobacter Pylori
Effect of Chicken Egg Antibody (IgY) on Patients With Chronic Gastritis
H. pylori positive patient volunteers that passed the selection criteria are recruited and divided into a test and a control group.
- Trial name
- NCT02721355
- Testing
- GastimunHP
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Immunology Research Institute in Gifu
Inflammatory Bowel Diseases, Colitis, Ulcerative
Chronic Care Model on Symptom Status, Stress and Quality of Life in Individuals With Inflammatory Bowel Disease
This study aims to evaluate the effects of nurse counseling provided based on the Chronic Care Model on symptom status, stress, and quality of life in individuals diagnosed with Inflammatory Bowel Disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohn Disease
- Trial name
- NCT06757231
- Testing
- Nurse Counseling Based on the Chronic Care Model (CCM)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Ulcerative Colitis, Ulcerative Colitis Chronic
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD).
- Conditions
- Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease
- Trial name
- SHINE-ON (NCT04844606)
- Testing
- Mirikizumab
- Where
- 69 sites in United States, Austria and 14 more
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company
Wounds
Effect of SACCHACHITIN on Healing of a Chronic Wound
SACCHACHITIN gel, prepared from the waste residue of the fruiting body of Ganoderma tsugae, was used in a previous study to enhance skin wound healing in animal models.
- Trial name
- NCT00117364
- Testing
- SACCHACHITIN patch
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Min-Sheng General Hospital
Morbus Crohn, Colitis, Ulcerative
Acupuncture in Pediatrics and Adolescents With Chronic Inflammatory Bowel Diseases
Chronic inflammatory bowel disease (CIBD) with its prevalence of 2.6 million people in Europe is diagnosed in 25% before the age of 18 years.
- Trial name
- NCT04488198
- Testing
- Acupuncture
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Diabetic Foot Ulcers, Venous Stasis Ulcer
Negative Pressure Wound Therapy Registry
The goal of the Negative Pressure Wound Therapy Registry (NPWTR) for Wounds is to provide real world patient data from electronic health records submitted to meet Stage 2 Meaningful Use in order to understand the effectiveness…
- Conditions
- Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence
- Trial name
- NPWTR (NCT02467998)
- Testing
- NPWT
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- U.S. Wound Registry
Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
Analysis of Barriers and Facilitators to Adapted Physical Activity for Pediatric Patients With Chronic Inflammatory Bowel Diseases
This study aims to identify perceived barriers and facilitators to regular physical activity among children and adolescents with inflammatory bowel disease (IBD) followed in pediatric gastroenterology.
- Trial name
- Feels-Mici (NCT07383844)
- Testing
- IMPACT-III questionnaires, Data collection: CAPAS-Q, semi-structured interview
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Lenval