Clinical trials: Clinical Research
Complete Tear, Knee, Anterior Cruciate Ligament
A Study to Compare Two Techniques for the Reconstruction of the Anterior Cruciate Ligament
This is a prospective and randomized trial to compare two different techniques used in normal practice for the reconstruction of the anterior cruciate ligament in arthroscopy.
- Trial name
- ACL (NCT03746470)
- Testing
- ACL reconstruction preserving insertion, ACL reconstruction detaching insertion
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 85 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Iron Deficiency Anemia
Prevalence of Oral Manifestations of Iron Deficiency Anemia in a Sample of Egyptian Population
According to WHO Reportin 2002, iron deficiency anemia was considered to be the most important contributing factor to the global burden of anemia.
- Trial name
- NCT03365570
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Cairo University
Heart Septal Defects, Ventricular, Atrioventricular Septal Defect
Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow
Infants with congenital heart disease and increased pulmonary blood flow have altered carnitine homeostasis that is associated with clinical outcomes; and L-carnitine treatment will attenuate these alterations and improve…
- Trial name
- L-carn (NCT01825369)
- Testing
- IV L-carnitine
- Where
- United States
- Sponsor
- University of California, San Francisco
Medication Abortion, Telemedicine
TeleMAb Retrospective Cohort Study
The objective of this study is to evaluate whether there are different clinical outcomes and unscheduled follow-ups between in-person and telemedicine medication abortion, and to better understand patients' experiences with…
- Trial name
- NCT07405294
- Testing
- Telemedicine Medication Abortion
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Columbia University
Invasive Group A Beta-Haemolytic Streptococcal Disease
Paediatric European Group A Streptococcal United Study.
Introduction Since 2022 there are reports of a rapid increase in invasive group A streptococcal infections (iGAS) in children in some but not all European countries. Detailed information on this increase is lacking.
- Trial name
- PEGASUS (NCT06058117)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Noordwest Ziekenhuisgroep
Colorectal Cancer, Precancerous Condition
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of celecoxib may keep polyps and colorectal cancer from forming in patients with familial adenomatous polyposis.
- Trial name
- NCT00685568
- Testing
- celecoxib
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- M.D. Anderson Cancer Center
Myopia
Pilot Study of Neurovision to Improve Vision and Slow Myopia Progression in Children With Myopia
This is a pilot study to assess the effectiveness of Neurovision treatment in the improvement of vision in children being under-corrected and to assess the effectiveness of Neurovision treatment in slowing down myopia progression…
- Trial name
- NCT00348218
- Testing
- NeuroVision
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Diabetes, Diabetes Mellitus, Type 1
Observational Study With Mixtard® 30 NovoLet® to Assess Patient Satisfaction
This study is conducted in Asia. The aim of this study is to assess patient satisfaction after switching to biphasic human insulin 30 treatment using the NovoLet® insulin device as treatment for diabetes mellitus under normal…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01492218
- Testing
- biphasic human insulin 30
- Where
- Philippines
- Volunteers
- 1,330 people
- Sponsor
- Novo Nordisk A/S
Angelman Syndrome
Use of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman Syndrome
Angelman syndrome (AS) is a rare neurogenetic disorder that affects approximately 1 in 15,000 children - approximately 500,000 people worldwide.
- Trial name
- EYEANGEL (NCT06737718)
- Testing
- Eye tracking, Data collection from patients' medical files, questionnaires
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colonoscopy
Short Course, Single-dose PEG 3350 for Colonoscopy Prep in Children
The investigators propose to conduct a prospective study of a widely used bowel preparation regimen (polyethylene glycol 3350 + a sports drink) on pediatric patients who undergo a colonoscopy performed by the pediatric…
- Trial name
- NCT01518790
- Testing
- polyethylene glycol 3350
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Walter Reed National Military Medical Center
Migraine
A Trial to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents
The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment…
- Trial name
- NCT04530110
- Testing
- Fremanezumab
- Where
- 70 sites in United States, Canada and 7 more
- Volunteers
- 499 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D LLC
Bladder Cancer, Bladder Cancer Stage I
Loop Resection or Cold-cup Biopsy? A Study Comparing the Accuracy of Muscle Samples During Bladder Tumor Surgery
In this report the investigators compared two deep muscle sampling methods (Loop resection and Cold-Cup Biopsy) during endoscopic resection of bladder tumors for patients with suspected bladder cancer in Tygerberg hospital.
- Conditions
- Bladder Cancer, Bladder Cancer Stage I, TURBT
- Trial name
- NCT06796413
- Testing
- Loop Resection or Cold-cup biopsy
- Where
- South Africa
- Volunteers
- 120 people
- Sponsor
- University of Stellenbosch
End Stage Renal Disease
Prognostic Value of Central and BracHial Ambulatory Blood Pressure Monitoring in ERSD Patients Treated With HeMOdialysis
This is a prospective cohort study which aims to explore the significance of brachial and central ambulatory blood pressure monitoring in predicting cardiovascular risk in patients with end stage renal disease who are treated…
- Trial name
- C-HEMO (NCT03306160)
- Testing
- 48-hour blood pressure ambulatory monitoring
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Shanghai 10th People's Hospital
Bicuspid Aortic Valve Disease
Bicuspid Echocardiac Study Team（BEST）
The Chinese Bicuspid Aortic Valve (BAV) Ultrasound imaging cohort study is a Chinese BAV ultrasound imaging cohort study. At present, a retrospective study cohort involving more than 30 hospitals has been established.
- Trial name
- BEST (NCT05656820)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Suzhou Municipal Hospital
Atopic Dermatitis (AD)
A Phase 3 Study of MH004 Ointment in Patients With Mild to Moderate Atopic Dermatitis
This is a multicenter, randomized, double-blind, vehicle-controlled phase III study of MH004 Ointment with a 44-week open-label long-term safety extension period.
- Trial name
- NCT07185282
- Testing
- MH004 Ointment, Vehicle Ointment
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Minghui Pharmaceutical (Hangzhou) Ltd
Dietary Diversity
A Feasibility Study of Delivering Adolescent Nutrition Interventions Through School-Based Platforms in Ethiopia
Alive \& Thrive (A\&T) is an initiative that supports the scaling up of nutrition interventions to save lives, prevent illnesses, and contribute to healthy growth and development through improved maternal nutrition, breastfeeding…
- Trial name
- NCT04121559
- Testing
- School Interventions, Community Interventions, School System Interventions
- Where
- United States
- Volunteers
- 1,712 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Spinal Fusion, Spinal Stenosis
Spine Registration Using 3D Scanning
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
- Conditions
- Spinal Fusion, Spinal Stenosis, Scoliosis, Spondylolisthesis
- Trial name
- NCT05195580
- Testing
- Optical 3D Scanner
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Advanced Scanners Inc.
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hypersensitivity, Anaphylaxis
Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral Challenges
The goal of this exploratory study is to evaluate the effects of inhaled epinephrine in subjects, who may not be eligible for the GHL-101 trial, and who are experiencing systemic allergic reaction (SAR) that occur following…
- Trial name
- NCT07038746
- Testing
- Inhaled Epinephrine
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Dr. George Luciuk
Orthodontic Aligners
Difference Between Pressing and Vacuum Techniques in Fabrication of Orthodontic Aligners in Cases With Crowding: A Cross-sectional Study
This cross sectional study is aiming to compare 2 methods of clear aligner fabrication.
- Trial name
- NCT06231888
- Testing
- Aligner
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
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