Clinical trials: Clinical Study
Contraception
Improving Adherence to Postpartum Family Planning Guidance in Ghana
Evaluating a Postpartum Family Planning Package (PPFP) in a Hybrid Type II implementation study with a stepped-wedge design.
- Trial name
- NCT04306029
- Testing
- Postpartum Family Planning Package
- Where
- 3 sites in Ghana
- Volunteers
- 2,142 people
- Sponsor
- University of Pennsylvania
Prostate Cancer
The Physical Exercise and Prostate Cancer Study
The purpose of this study is to determine the effectiveness of a four months strength training program on physical and psychological health in patients with prostate cancer during androgen deprivation therapy.
- Trial name
- PEPC (NCT00658229)
- Testing
- Strength training group
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Primary Sjögren's Syndrome
Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome
This study consists of three consecutive parts. Part 1 in primary Sjögren's syndrome (pSS) patients (n=2-6) and Part 2 in healthy voluteers (n=3) are feasibility studies to assess if the selected [Zr-89]-rituximab PET/CT method…
- Trial name
- NCT02495129
- Testing
- VAY736 lower dose, VAY736 higher dose
- Sponsor
- Novartis Pharmaceuticals
Clostridium Enterocolitis, Antibiotic-Associated Diarrhea
Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment
What is the difference between the use of one drug (Oral Metronidazole) versus the use of this same drug combined with another drug (Rifampin) in treatment of bacteria and infection-associated diarrhea in patients? This infection…
- Conditions
- Clostridium Enterocolitis, Antibiotic-Associated Diarrhea, Pseudomembranous Colitis, Pseudomembranous Enterocolitis
- Trial name
- NCT00182429
- Testing
- Metronidazole and Rifampin
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
NEC, Necrotizing Enterocolitis
Study of Normal Intestinal Development and Disease in Premature and Term Neonates
Current research on early intestinal development is primarily performed in mouse models. While useful in many other ways, mouse models are not ideal for studying human intestine development as the timing of this process differs…
- Conditions
- NEC, Necrotizing Enterocolitis, Intestinal Disease, Human Development
- Trial name
- NiiCE (NCT06681129)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Pellucid Marginal Corneal Degeneration, Keratoconus
A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea
The purpose of this research study is to find out if the new Brillouin Ocular Scanner can measure the variation (difference) of the corneal elastic changes involved in the onset of corneal ectasia, induced by LASIK surgery and…
- Conditions
- Pellucid Marginal Corneal Degeneration, Keratoconus, Keratectasia
- Trial name
- NCT03220529
- Testing
- Brillouin Ocular Scanner
- Where
- 2 sites in United States, Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neuromuscular Blocking Agents Anaphylaxis
Allergy to Neuromuscular Blocking Agents and Pholcodine Exposure
The main objective of this study is to compare pholcodine exposure in patients having presented with a perianaesthetic anaphylactic reaction to a NMBA (cases) to pholcodine exposure in matched anaesthetised patients with…
- Trial name
- ALPHO (NCT02250729)
- Testing
- intradermal pholcodine allergy test in cases, Blood sampling
- Where
- 24 sites in France
- Volunteers
- 1,020 people
- Sponsor
- Central Hospital, Nancy, France
Cervical Cancer, Condylomata Acuminata
An Immuno-bridging Study of a Nonavalent HPV Vaccine (E.Coli) in Healthy Population Aged 9-17 vs Aged 18-26 Years Old
This is a open label clinical trial to evaluate the safety and immunogenicity of a Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58)Vaccine(E.Coli) manufactured by Xiamen Innovax Biotech CO., Ltd., in…
- Trial name
- NCT05056402
- Testing
- 3 doses of the Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), 2 doses of theRecombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)
- Where
- China
- Volunteers
- 1,382 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Pediatric Multiple Sclerosis
ATOMIC (Active Teens With MultIple sClerosis) Teens: A Feasibility Study
Taking part in recommended levels of physical activity in youth with MS may have an important and positive impact on disease symptoms, long-term disability and health outcomes. Unfortunately, youth with MS are highly inactive.
- Trial name
- NCT03137602
- Testing
- ATOMIC mobile app
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- The Hospital for Sick Children
Fibroelastosis
Lung Transplantation for Pleuroparenchymal Fibroelastosis
This retrospective observational study will evaluate the outcomes of lung transplantation for a rare cause of interstitial lung disease called pleuroparenchymal fibroelastosis.
- Trial name
- NCT05044390
- Testing
- Lung transplantation (single, lobar or bilateral lung transplantation)
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Bullying
Group Social Work Intervention in Improving Peer Relationships
The aim of this mixed-methods study is to examine the effect of a group social work intervention, based on cognitive behavioral therapy, on bullying-related cognitions and peer relationships among boys in institutional care.
- Trial name
- NCT07057960
- Testing
- Group Social Work Intervention Based on Cognitive Behavioral Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Infection in Solid Organ Transplant Recipients
Valganciclovir Dosing in Pediatric Solid Organ Transplant Recipients
Valganciclovir is extensively used for cytomegalovirus (CMV) infection treatment and prophylaxis after solid organ transplantation (SOT). VGC dosing is problematic in children.
- Trial name
- NCT02503982
- Testing
- prophylactic Valganciclovir
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Rabin Medical Center
Brain Injuries, Brain Diseases
Treating Chronic Symptoms of Pediatric Acquired Brain Injury - a Feasibility Study
Children with acquired brain injury (ABI) often struggle with complex impairments, including cognitive (such as memory and attention), social, emotional and behavioral challenges.
- Conditions
- Brain Injuries, Brain Diseases, Family, Child
- Trial name
- CICI (NCT04186182)
- Testing
- CICI - Feasibility trial study group
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Diastasis Recti
Evaluation of the Long-term Stability of Sheath Plication Using Absorbable Sutures in Patients With Diastasis of the Recti Muscles: an Ultrasonography Study
A comparative prospective study assessing the outcomes of recti muscle diastasis correction with absorbable suture.
- Trial name
- NCT01586559
- Where
- Czechia
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Bulovka Hospital
HIV Infection
An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection: Canada
This study is being conducted to assess the safety and tolerability of an oral liquid solution of Sustiva for antiretroviral therapy-naive or therapy-experienced HIV-1 infected children between the ages of 3-16 who are failing or…
- Trial name
- NCT00162188
- Testing
- Efavirenz
- Where
- 4 sites in Canada
- Sponsor
- Bristol-Myers Squibb
Osteoporosis, Treatment Failure
Incidence of the Treatment faIlure in Osteoporosis
Osteoporotic fractures are associated with significant morbidity, increased mortality and reduction in the quality of life, available treatments reduces the fracture risk between 30 and 70%, however some patients experience a new…
- Trial name
- TAILOR (NCT05499403)
- Where
- Switzerland
- Volunteers
- 415 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Diaper Dermatitis
Effect of Breast Milk on Diaper Dermatitis in Infants
Diaper dermatitis, one of infants' most common health problems, can be treated with various methods. One of these methods is breast milk.
- Trial name
- dermatit (NCT06699303)
- Testing
- Use of diaper rash cream containing Hamamelis virginiana (potency 12mg/100g) 5.35 g / 100 g for infants in the control group in diaper dermatitis care
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Pervasive Developmental Disorder
Study of Aripiprazole in the Treatment of Pervasive Developmental Disorders
The purpose of this study is to develop a better tolerated and more effective pharmacologic treatment with individuals with Pervasive Developmental Disorder.
- Trial name
- NCT00870727
- Testing
- Aripiprazole oral product
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Indiana University
Epileptic Seizure
A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI
1. By following up the prognosis of surgical patients, the application value of Cortex ID quantitative analysis in the localization of epilepsy foci was studied. 2.
- Trial name
- NCT05567042
- Testing
- No intervention
- Volunteers
- 50 people
- Sponsor
- Li Shuangshuang
Influenza
ADITEC FLU STUDY: Understanding the Genetic Basis for Immune Responses
Infants and young children do not respond as well as adults to the flu vaccines currently available in the UK. Fluad, is a different type of influenza vaccine that has been available in the European continent for the last decade…
- Trial name
- NCT01682369
- Testing
- TIV (Aggripal), ATIV (Fluad)
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oxford
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