Clinical trials: Clostridioides Difficile
Clostridium Difficile Infection
Fecal Microbiota Transplant by Oral Capsules With Lactobacilli for Recurrent Clostridium Difficile Infection
Investigators designed an open, two-arm study to compare fecal microbiota transplant by oral capsules (FMT-c ) versus FMT-c enriched with Lactobacillus for treatment of C. difficile recurrent infection
- Trial name
- NCT03804736
- Testing
- FMT-c, FMT-c Lactobacillus
- Volunteers
- 21 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Diarrhea
Hospital Onset Diarrhoea Investigation
This service evaulation aims to investigate how common diarrhoea is in hospital patients on medical, surgical and elderly care wards, what it is due to and how it is managed.
- Trial name
- HOODINI (NCT03321578)
- Where
- 24 sites in United Kingdom
- Volunteers
- 230 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Clostridium Difficile Infection
Novel Biomarkers to Predict Outcome in Clostridium Difficile Infection
Acquiring diarrhoea in hospital is a serious problem and most frequently occurs when susceptible patients receive antibiotics as part of their (often life-saving) care.
- Trial name
- NCT02086916
- Where
- United Kingdom
- Volunteers
- 122 people
- Sponsor
- Barts & The London NHS Trust
Bacterial Infections
Hospital Wide Roll-Out of Antimicrobial Stewardship
Dramatic increases in antibiotic utilization in hospitals continue to drive antibiotic resistance among hospital-acquired pathogens. However, 30-50% of the antibiotic use in hospitals is unnecessary or inappropriate.
- Trial name
- NCT01587937
- Testing
- Antibiotic stewardship audit-and-feedback to prescribers of patients receiving 3rd or 10th day of targeted broadspectrum antibiotics
- Where
- Canada
- Volunteers
- 19,220 people
- Sponsor
- Sunnybrook Health Sciences Centre
Clostridium Difficile
To Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Difficile) Involvement in the Pathogenesis
The objective of this multi-center, prospective observational study is to determine the feasibility of a potential interventional study with fidaxomicin.
- Trial name
- DAISY (NCT01533844)
- Where
- 9 sites in France, Germany and 2 more
- Volunteers
- 1 people
- Sponsor
- Astellas Pharma Europe B.V.