Clinical trials: Cognitive Dysfunction, Cognitive Disorder
Consciousness Disorder, Cognitive Impairment
Neurophysiological Evaluation of Residual Cognitive Functions in Patients With Severe Alterations of Consciousness
Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.
- Trial name
- NCT05802524
- Testing
- Neurowave Group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Dementia, Mild Cognitive Impairment
Prospective Research in Memory Clinics (PRIME)
The purpose of the PRIME Study is to examine the current management and outcomes of patients with mild cognitive impairment or dementia.
- Trial name
- NCT00297271
- Testing
- Current treatment practice of each participating physician
- Where
- 9 sites in Australia
- Volunteers
- 970 people
- Sponsor
- Janssen-Cilag Pty Ltd
Parkinson Disease, Executive Dysfunction
Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease
The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.
- Trial name
- NCT03285347
- Testing
- Computer-based cognitive training
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Anti-NMDA Receptor Encephalitis
Antibody-mediated NMDA Receptor Encephalitis: Symptoms, Biomarkers, and Mechanisms of the Prolonged Recovery Stage
The encephalitis mediated by antibodies against the NMDA receptor (NMDARe) predominantly affects young adults and children resulting in severe neurologic and psychiatric deficits.
- Trial name
- AMENDS (NCT06183788)
- Testing
- Remote cognitive rehabilitation program
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Chemotherapy-Related Cognitive Impairment, Chemotherapeutic Toxicity
Investigating Cognitive Impairment in Young Patients With Cancer Prospectively
The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer.
- Conditions
- Chemotherapy-Related Cognitive Impairment, Chemotherapeutic Toxicity, Chemo-brain, Cancer
- Trial name
- MyBrain (NCT05840575)
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obstructive Sleep Apnea, Alzheimer Disease
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in…
- Conditions
- Obstructive Sleep Apnea, Alzheimer Disease, Vascular Dementia, Mild Cognitive Impairment
- Trial name
- ENCHANT (NCT04335994)
- Testing
- In-laboratory polysomnography, Home Sleep Apnea Test
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Growth Failure, Atopy
The PREWEAN Study. Weaning of Preterm Infants During the First Year of Life.
In this Austrian observational study preterm infants born with a birth weight <1500 g and a gestational age <32 weeks will be investigated at the neonatal outpatient clinic.
- Conditions
- Growth Failure, Atopy, Adiposity, Cognitive Impairment
- Trial name
- PREWEAN (NCT02936219)
- Where
- Austria
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
Tau/P-Tau and Neurocognitive Outcomes in Children
The proposed studies are aimed to measure Tau and P-Tau levels in pre- and postoperative blood, urine, feces and saliva, as well as to assess pre- and postoperative neurocognitive function in children (3 to 5 years old) who will…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
- Trial name
- NCT03511729
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment
An Intergenerational, Cognitively Enriched Intervention for MCI Patients and Their Children.
In 2018, approximately 50 million people received a diagnosis of dementia, which is projected to triple by 2050. To mitigate the increase in dementia, it is crucial to prevent cognitive decline in at risk groups, such as older…
- Trial name
- MCI-project (NCT06221579)
- Testing
- No intervention, interviews with MCI patients as part of the development phase
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Ghent
Erectile Dysfunction
Evaluation for Restoration of Erectile Dysfunction After Cardioversion Treatment Trial
Erectile and Cognitive function by using the questionnaire and assessment form before sinus conversion
- Trial name
- NCT02742896
- Testing
- Erectile dysfunction
- Where
- South Korea
- Sponsor
- Yong Seog Oh
Duarte Galactosemia
Intervention and Outcomes in Duarte Galactosemia
The purpose of this study is to learn about Duarte galactosemia (DG). This study will examine the possible effects of Duarte galactosemia (DG) in children, and determine whether dietary exposure to milk in infancy or early…
- Trial name
- NCT02519504
- Where
- United States
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Emory University
Relapsing-Remitting Multiple Sclerosis
GER-009-06-AVX Early Therapy in Multiple Sclerosis
This study is being done to increase awareness for early therapy with Avonex for Multiple Sclerosis (MS) and the cognitive dysfunction that accompanies MS, and to record safety data for Avonex.
- Trial name
- FIT (NCT00492570)
- Volunteers
- 230 people
- Sponsor
- Biogen
Neurodegenerative Diseases, Parkinson Disease
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease
- Trial name
- MARKERS-NDD (NCT06596746)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Casa di Cura San Raffaele Cassino
Premature Infant
Cincinnati Infant Neurodevelopment Early Prediction Study (CINEPS)
The Early Prediction Study is a longitudinal population-based cohort study for very preterm infants ≤32 weeks gestational age. Preterm infants recruited from three greater Cincinnati and two Dayton area neonatal intensive care…
- Trial name
- NCT03345069
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Mild Cognitive Impairment, Attention Impaired
The Effect of Body Percussion Training on Neuromotor Performance, Attention, and Functionality in Adolescents With Mild Intellectual Disability
The aim of this randomized controlled trial is to investigate the effects of group-based rhythm-based body percussion training on neuromotor performance, attention, and functionality in adolescents with mild intellectual…
- Conditions
- Mild Cognitive Impairment, Attention Impaired, Adolescent Development
- Trial name
- NCT07554144
- Testing
- Rhythm-based body percussion training group, Control group (passive listening) group
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Kutahya Health Sciences University
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Transient Ischemic Attack, Stroke
Post-stroke Triage "DOC": Simple Screening for Depression, Obstructive Sleep Apnea and Cognitive Impairment
The purpose of this study is to determine whether simple, evidence-based clinical screening be quickly and feasibly implemented (>85% of patients in an average of <6 minutes) in large-volume urgent transient ischemic attack…
- Conditions
- Transient Ischemic Attack, Stroke, Depression, Obstructive Sleep Apnea
- Trial name
- NCT02007265
- Where
- Canada
- Volunteers
- 1,504 people
- Sponsor
- Sunnybrook Health Sciences Centre
Dementia
IDEA Study Cognitive Stimulation Therapy (CST) Trial in Nigeria
This trials of cognitive stimulation therapy (CST) in Tanzania is part of the larger Identification and Intervention for Dementia in Elderly Africans (IDEA) study.
- Trial name
- IDEA (NCT02233530)
- Testing
- CST intervention
- Where
- Nigeria
- Volunteers
- 8 people
- Sponsor
- William Keith Gray
Physical Disability, Cognitive Dysfunction
Evaluation of mediVR-KAGURA Guided Therapy
The objective is to evaluate mediVR-KAGURA guided therapy for the treatments of physical and cognitive dysfunctions regardless of baseline disease in a prospective interventional design.
- Trial name
- NCT04562662
- Testing
- mediVR KAGURA
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Japan Society of Clinical Research