Clinical trials: Cognitive Functions
Sedentary Behaviors, Physical Inactivity
Effects of Virtual Reality and Traditional Exercise on Cognitive and Physical Performance in Sedentary Adults
This study aimed to compare the effects of virtual reality (VR)-based exercise and traditional exercise methods on selected physiological and cognitive parameters in sedentary individuals.
- Trial name
- VR-TRAD-EX (NCT07567144)
- Testing
- Virtual Reality Exercise Training, Traditional Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Parkinson Disease
Acute Effects of Cycling Dual-task in Parkinson´s Disease.
Taking into account the process of functional and cognitive evolution that patients with Parkinson's disease experience throughout the pathology, the objective of this study is to evaluate the acute effects of aerobic exercise in…
- Trial name
- NCT05375032
- Testing
- Cycling combined with cognitive tasks, Cycling
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Vigo
Parkinson Disease, Huntington Disease
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders
Mild cognitive impairment associated with movement disorders occurs in up to one third of patients in early stages of the disease, and confers an increased risk of developing dementia.
- Trial name
- CogMusT (NCT05769972)
- Testing
- Immersive Virtual Reality (Parkinson's disease), Computer-based cognitive rehabilitation (Parkinson's disease), Computer-based cognitive rehabilitation (Huntington's disease)
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Healthy
Explore the Nature Factors Relevant to Learning-Pioneering Natural Factors That Influences Science Learning II
Genetic research has provided the most exciting breakthroughs in neuroscience and cognitive science. Partially genetically determined cognitive impairments have been described in people with COMT, 5HT6, BDNF (Swillen et al.…
- Trial name
- NCT00713570
- Where
- Taiwan
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy, Spastic, Hemiplegia, Spastic
Changes in Motor and Cognitive Function on Unilateral Spastic Cerebral Palsy, Associated With Videogame Therapy
The use of interactive applications associated with position and movement sensors has begun to spread as an option for the reinforcement of physical rehabilitation therapies in patients with congenital or acquired motor disorders…
- Trial name
- NCT05557305
- Testing
- Videogame therapy, Conventional therapy
- Where
- Mexico
- Volunteers
- 84 people
- Sponsor
- Universidad Nacional Autonoma de Mexico
Activity, Motor
Feasibility and Fidelity of a Gross Motor-based Physical Activity Intervention on Cognition in Preschool-age Children
The goal of this study will be to examine the implementation and preliminary efficacy of a teacher taught gross motor skill-based physical activity (PA) intervention on cognitive variables in low low socio-economic (SES)…
- Trial name
- P-MAC (NCT05949866)
- Testing
- Movement and Cognition Intervention Group, Health Tracker Group (Control Group)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Alzheimer Disease
Differential Effects of Various Anesthetic Agents on Cognitive Function in Patients With Alzheimer's Disease
The objective of the study is to determine the effects of different anesthetic agents on cognitive function in patients with Alzheimer's disease (AD).
- Trial name
- NCT01870453
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Clinical High Risk for Psychosis
Targeted Cognitive Training in Clinical High Risk (CHR) for Psychosis
This project is a randomized-controlled trial to test the efficacy of computer-based targeted cognitive training (TCT) versus a placebo intervention of commercial computer games in adolescent/young adults at clinical high risk…
- Trial name
- NCT02404194
- Testing
- Targeted Cognitive Training, Computer Games
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Rush University Medical Center
Congenital Heart Disease, Frailty
Frailty and Non-Fragile Congenital Heart Disease
Congenital heart disease (CHD) is defined as congenital functional or anatomical abnormalities of the heart and intrathoracic great vessels.
- Trial name
- NCT05824650
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Hacettepe University
Transcutaneous Vagal Nerve Stimulation (tVNS), Parkinson Disease (PD)
Effects of Transcutaneous Vagus Nerve Stimulation in Parkinson´s Disease
This study aims to determine whether electrical stimulation of the ear, when combined with physical and speech therapy, can improve symptoms in subjects diagnosed with Parkinson´s disease, by comparing two different application…
- Trial name
- tVNS_PD (NCT07588191)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) of Vagus Nerve, Conventional Physical therapy, Conventional Speech Therapy
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universidade da Coruña
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common…
- Trial name
- NCT00916851
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive/Functional Effects, Metastatic Cancer
Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases
RATIONALE: Assessment of patients undergoing radiation therapy may help to determine the effects of the treatment and may help improve cancer treatment.
- Conditions
- Cognitive/Functional Effects, Metastatic Cancer, Radiation Toxicity
- Trial name
- NCT00007007
- Testing
- management of therapy complications, quality-of-life assessment
- Where
- 241 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- Radiation Therapy Oncology Group
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Cognitive Change, Beta-Thalassemia
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia
This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related quality of life measures in children with beta thalassemia.
- Conditions
- Cognitive Change, Beta-Thalassemia, Fatigue, Quality of Life
- Trial name
- NCT05469230
- Where
- Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Cairo University
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Alzheimer's Disease, Gait Apraxia
Alzheimer's Disease and Related Disorders
The purpose of this study is to compare characteristics of gait and balance measured among patients with Alzheimer's disease or related disorders separated into 3 groups according to the stage of disease (i.e., pre-dementia, mild…
- Conditions
- Alzheimer's Disease, Gait Apraxia, Impaired Cognition
- Trial name
- MERE (NCT01315704)
- Testing
- Drug intervention
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cognitive Impairment, Mild, Sleep
Are Cognition and Sleep Affected by Exposure to Carbon Dioxide and Bio Effluents During Sleep?
The aim of the project is to examine whether children's sleep and cognition are affected by exposure to CO2 and other bio effluents during sleep.
- Conditions
- Cognitive Impairment, Mild, Sleep, Environmental Exposure
- Trial name
- NCT03558698
- Testing
- Good ventilation, Ventilation CO2, Poor Ventilation
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mild Traumatic Brain Injury
Photobiomodulation for Concussions: the Use of the ImPACT® Test as an Assessment Tool
Brain photobiomodulation (PBM) therapy is an innovative modality for the stimulation of neural activity in order to improve brain function and is currently under investigation as a treatment for several diverse neurological…
- Trial name
- NCT04823507
- Testing
- BIOFLEX DUO+
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Meditech Rehabilitation Centre
Prader-Willi Syndrome
Stress and Brain Response Using MEG in PWS
Individuals with Prader-Willi Syndrome (PWS) have increased hunger and food seeking behaviour, as well as learning (cognitive) challenges.
- Trial name
- NCT04032639
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cerebral Palsy, Cerebral Palsy, Spastic
Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy
Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations.
- Trial name
- HABIT-ILE (NCT07253857)
- Testing
- GROUP -A , Hand and Arm Bimanual Intensive Therapy Including Lower Extremity, GROUP-B , Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
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