Clinical trials: Cognitive Functions
Lupus Erythematosus, Systemic, Gastrointestinal Microbiome
Assessment of Cognitive Function and Gut Microbiota Analysis in Real World Patients With Lupus Cerebrovascular Disease
Based on clinical manifestations, laboratory data and intestinal microflora detection, the cognitive function characteristics of patients with systemic lupus erythematosus and cerebrovascular disease and its relationship with…
- Trial name
- NCT05636670
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Obese, Healthy
Brain Fuel - Morning Nutrition and Cognitive Function
This study will help us learn more about how what a child eats can affect how their brain works.
- Trial name
- NCT03386396
- Testing
- High protein/low carbohydrate, High carbohydrate/low protein
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Healthy
Effects of Docosahexaenoic Acid (DHA) on Cognitive Function in Children 4 Years of Age
The primary objective of this study is to determine whether a 4-month period of supplementation with 400 mg/day of docosahexaenoic acid (DHA) provided from chewable softgel capsules containing bubblegum flavored microalgal oil…
- Trial name
- NCT00351624
- Testing
- DHA
- Where
- 10 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Cognitive Impairment, Dementia
Predicting MRI Abnormalities With Longitudinal Data of the Whitehall II Substudy
Follow-up study within the Whitehall II study, selecting 800 participants for further neuropsychological, clinical and imaging (MRI) examinations to examine brain structure and function in relation to age-related diseases and the…
- Conditions
- Cognitive Impairment, Dementia, Affective Disorders
- Trial name
- NCT03335696
- Where
- United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Attention Deficit Disorder With Hyperactivity
Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder
This study will evaluate the effectiveness of a single drug versus a combination of drugs in treating attention deficit hyperactivity disorder in children.
- Trial name
- Project1 (NCT00429273)
- Testing
- Guanfacine, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of California, Los Angeles
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Depression in Adolescence, Adverse Childhood Experiences
Shaping Actions and Responses to Emotions
The primary objective of this research is to examine two brief interventions for depression, Behavioral Activation (BA), and Problem Solving Therapy (PST), to investigate whether exposure to adverse childhood experiences…
- Trial name
- ShARE (NCT04719949)
- Testing
- Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
Cognitive Impairment, Variable
The Effect of Cognitive Rehabilitation on Cognitive Skills, Academic Performance And Quality of Life in Refugee Children
Children are the most vulnerable group to be affected by war. The long-term effects of exposure to conflict on children's mental, physical and cognitive development have been documented in the context of war and refugee camps.
- Trial name
- NCT05093738
- Testing
- Cognitive Rehabilitation
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Autism Spectrum Disorder
High School SUCCESS: Vocational Soft Skills Program for Transition-Age ASD Youth
By utilizing community-based participatory research methods, this research was conducted in collaboration with the community through our partnership of researchers, educators, providers and consumers (Active Collaborative Hub for…
- Trial name
- TAY SUCCESS (NCT04953793)
- Testing
- TAY SUCCESS, Usual Care
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Rady Children's Hospital, San Diego
Obesity, Childhood, Overweight, Childhood
Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function
The investigators aim to assess the relationship between overweight/obesity and decreased cognitive function in adolescents. While this relationship has been seen in past literature, the causal mechanisms are still unclear.
- Trial name
- NCT04346433
- Testing
- Restricted Sleep, Adequate Sleep
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Intellectual Disability, Mild
Evaluation of CO-OP for Adolescents With Mild Intellectual Disability
Intellectual disability (ID) affects a person throughout life and includes difficulties to manage what is expected in everyday life based on age.
- Trial name
- CO-OPIF (NCT06691698)
- Testing
- The Cognitive Orientation to Daily Occupational Performance Approach
- Where
- 2 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Pediatric-Onset Multiple Sclerosis (POMS)
Dual-Task Training in Pediatric Multiple Sclerosis
This randomized controlled trial aims to investigate the effects of an 8-week dual-task exercise training program compared to conventional functional exercise training on motor and cognitive functions in adolescents with…
- Trial name
- DTT-POMS (NCT07571304)
- Testing
- Dual-Task Exercise Training, Conventional Functional Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istanbul University - Cerrahpasa
Bardet-Biedl Syndrome
Characterizing the Genotype and Phenotype in Adults With Bardet-Biedl Syndrome
Bardet-Biedl syndrome (BBS; OMIN #209900) is a rare genetic disorder characterized by six core features: rod-cone dystrophy (retinitis pigmentosa), polydactyly, obesity, genital anomalies, renal anomalies, and learning…
- Trial name
- NCT05400278
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo University Hospital
Moderate Acute Malnutrition
Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old
The aim of this open-label randomized controlled trial conducted in four African countries (Madagascar, Niger, Central African Republic and Senegal) is to compare three strategies of renutrition for moderate acute malnutrition…
- Trial name
- MALINEA (NCT03474276)
- Testing
- Azythromycin, Inuline and fructo-oligosaccharides, Albendazole
- Where
- 4 sites in Central African Republic, Madagascar and 2 more
- Volunteers
- 1,357 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Stroke
Effect of Donepezil on the Reorganization of Cognitive Neural Network in Patients With Post-Stroke Cognitive Impairment
The purpose of this study is to demonstrate the efficacy and safety of donepezil on the recovery of cognitive function in patients with stroke and to delineate the neurophysiologic mechanisms of the therapeutic effect of…
- Trial name
- NCT00530478
- Testing
- Donepezil
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Deaf Children, Cochlear Implant
Assessment of the Development of Social Cognition in a Deaf Child With a Cochlear Implant : A Study Using a Standardized Questionnaire
This study investigates the adaptability of a questionnaire assessing social cognition in children with cochlear implants aged 3 to 6 years, implanted before the age of 15 months.
- Trial name
- 1OL1 (NCT06914531)
- Testing
- Questionnaire comprehension test
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS)
Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction
Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional…
- Conditions
- Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS), Functional Dyspepsia
- Trial name
- PIPPI (NCT07319078)
- Testing
- Gut-directed hypnotherapy, Cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Intracranial Aneurysm
Evaluation of Postoperative Cognitive Function, Anxiety, Depression and Quality of Life in Patients With Unruptured Intracranial Aneurysms
This prospective single-center cohort study aims to identify the incidence of cognitive dysfunction after unruptured aneurysm operation and explore the influencing factors.
- Trial name
- NCT03494608
- Volunteers
- 350 people
- Sponsor
- Xuanwu Hospital, Beijing
Epilepsy
Lamotrigine Cognitive Function Study in Adult Untreated Epilepsies
The purpose of this study is to compare the effect of anti-epileptic drugs' (AEDs) long-term treatment on cognitive function. This study is an open-label, randomized, multicenter comparative trial of lamotrigine versus…
- Trial name
- NCT00896987
- Testing
- lamotrigine (Lamictal), Carbamazepine (Tegretol)
- Where
- South Korea
- Volunteers
- 121 people
- Sponsor
- Korean Epilepsy Society
Brain Structural Connectivity, Cognitive Function
Developmental Trajectory of Brain Structural Connectivity and Cognitive Function From Childhood to Adulthood
Magnetic resonance imaging (MRI) is a premier modality to investigate structures and functions of human brain. In studies of children and adolescents, noninvasiveness of MRI makes it especially applicable.
- Trial name
- NCT01677793
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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