Clinical trials: Cognitive Functions
Drug Addiction
Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old.
- Trial name
- NCT05958641
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Physical Activity, Cardiometabolic Health
Optimizing Cardiometabolic Health, Cognition and Academic Performance in Children (HAPHC)
Children and young people are moving less and less. In combination with an unhealthy diet, this has led to a sharp increase in overweight and obesity among children worldwide.
- Trial name
- NCT04956003
- Testing
- 45-minute daily physical activity
- Where
- Austria
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Child Development, Child Behavior
Effects of Psychosocial Stimulation and Cash on Children's Development and Behaviour
Burden: In developing countries, an estimated 219 million children do not reach their maximum potentiality because of poverty and associated risk factors.
- Trial name
- NCT03281980
- Testing
- Psychosocial stimulation (PS), Government Intervention (UCT+HE)
- Where
- Bangladesh
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Stem Cell Transplant, Late Effect
Monitoring Neurocognitive Dysfunction and the Impact of Metabolism and Physical Capacity After Paediatric HSCT
Today the overall survival of childhood cancers has increased to above 85%. This increase is partially caused by treatment with bone marrow transplantation.
- Conditions
- Stem Cell Transplant, Late Effect, Neurocognitive Dysfunction, Paediatric Patients
- Trial name
- MindMe (NCT07140445)
- Where
- Denmark
- Volunteers
- 175 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autistic Disorder, Autism Spectrum Disorder
Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
This study will investigate and confirm the efficacy of two psychological treatments for adults with autism spectrum disorder. Cognitive Enhancement Therapy (CET) is a cognitive remediation intervention that aims to help adults…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Asperger Syndrome, Pervasive Developmental Disorder
- Trial name
- PerspectivesII (NCT03170453)
- Testing
- Cognitive Enhancement Therapy, Enriched Supportive Therapy
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Pittsburgh
Cognitive Function and Well-Being
Acute Physical Exercise Intensity on Adolescents Cognitive Function
Cognitive function and psychological well-being are two variables related to academic performance. Several studies have shown that these variables are sensitive to acute physical exercise, but it is not known which doses of…
- Trial name
- APICA (NCT03441386)
- Testing
- Physical Exercise Session
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Alzheimer's Disease
Effect of REST in the Alzheimer Disease Continuum
The investigators assume that REST gene polymorphism affects REST protein concentration, and REST protein concentration in peripheral blood is related to cognitive function and hippocampus.
- Trial name
- ERADC (NCT03884023)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Obese, Healthy
Brain Fuel - Morning Nutrition and Cognitive Function
This study will help us learn more about how what a child eats can affect how their brain works.
- Trial name
- NCT03386396
- Testing
- High protein/low carbohydrate, High carbohydrate/low protein
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Schizophrenia
Effects of Buspirone Combined With Clozapine
This study aimed to evaluate the enhancing effects of different doses of buspirone on psychiatric symptoms and cognitive function in patients with schizophrenia.
- Trial name
- NCT06906224
- Testing
- Low-dose group (buspirone tablets, clozapine), High-dose group (buspirone tablets, clozapine)
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Chuanfu Song
Duchenne / Becker Muscular Dystrophy
Transition to Adulthood in People With Muscular Dystrophy
The study will involve boys with Duchenne Muscular Dystrophy (DMD), from adolescence to adulthood living in Italy, and their families/ caregivers.
- Trial name
- TAMDY (NCT07101185)
- Testing
- VIRTUAL REALITY
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Eugenio Medea
Huntington Disease
Wearable Sensors for Quantitative Assessment of Motor Impairment in Huntington's Disease Huntington's Disease
The principal means of measuring motor impairment in Huntington disease (HD) is the Unified Huntington's Disease Rating Scale (UHDRS) total motor score, which is subjective, categorical, requires significant training to…
- Trial name
- NCT03599076
- Testing
- HD Wear
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BioSensics
Moyamoya Disease, Revascularization
The Evolution and Prognosis of Moyamoya Disease
To investigate the evolution of imaging appearances and cognitive function of Moyamoya disease (MMD) and to establish a prognosis evaluation system based on imaging biomarkers in MMD.
- Conditions
- Moyamoya Disease, Revascularization, Cognitive Impairment, Functional Impairment
- Trial name
- NCT05619068
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Partial Epilepsy
Effects of Eslicarbazepine Acetate (Esl, Bia 2-093) on Cognitive Function in Children With Partial Onset Seizures
To evaluate the effects of eslicarbazepine acetate on cognition in comparison with placebo as adjunctive therapy in children aged 6 to 16 years old with refractory partial-onset seizures.
- Trial name
- NCT01527513
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- 36 sites in Italy, Netherlands and 3 more
- Volunteers
- 123 people
- Sponsor
- Bial - Portela C S.A.
Autism Spectrum Disorder, Autism
Cognitive-Behavioral Therapy for Children With High-Functioning Autism Spectrum Disorder and Anxiety
Many children and adolescents with autism spectrum disorder (ASD) experience high levels of anxiety which can further inhibit their ability to master developmental tasks such as succeeding in school and developing and maintaining…
- Conditions
- Autism Spectrum Disorder, Autism, Asperger Syndrome, PDD-NOS
- Trial name
- NCT01187784
- Testing
- Coping Cat cognitive-behavioral therapy for anxious youth
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Alliant International University
Epilepsy
Neural Basis of Cognition
The overall purpose of this study is to better understand human cognition and human epilepsy by working with patients undergoing clinical treatment for pharmacologically resistant epilepsy.
- Trial name
- NCT05132543
- Testing
- High density micro-electrocorticography for neural speech prothesis
- Volunteers
- 38 people
- Sponsor
- Duke University
Growth & Development, Obesity
Effects of Infant Egg Consumption on Child Health and Cognition Development
The objective of this study is to examine how infant egg consumption (age of introduction and frequency of intake) influences physical growth, obesity, cardio-metabolic health, risk of food allergy, and cognition development in…
- Conditions
- Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome
- Trial name
- NCT04345185
- Testing
- Infant egg consumption (i.e., age of introduction and frequency of intake)
- Where
- United States
- Volunteers
- 5,374 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Autism
Multisensorial Information's Treatment in Autism Spectrum Disorder
Introduction: Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors.
- Trial name
- NCT02579109
- Testing
- memory test
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Celiac Disease in Children, Gluten Allergy
Mental Perfomance in Patients With Coeliac Disease
Coeliac disease (CD) is an immune-mediated systemic disorder triggered by gluten in genetically predisposed patients. The only available treatment is a strict life long gluten-free diet (GFD), which has been linked to a reduced…
- Trial name
- NCT06519916
- Testing
- Assessment of mental performance
- Where
- Switzerland
- Volunteers
- 444 people
- Sponsor
- University Children's Hospital Basel
Delirium, Cognitive Impairment
Validation of the PreSchool Confusion Assessment Method for the Intensive Care Unit (psCAM-ICU)
The investigators hypothesize that critical care trained registered nurses and physicians can perform measurements of cognitive impairment in critically ill pediatric patients in a reliable and valid manner.
- Trial name
- NCT02481115
- Volunteers
- 300 people
- Sponsor
- Vanderbilt University
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