Clinical trials: Cognitive Functions
Obstructive Sleep Apnea, Alzheimer Disease
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in…
- Conditions
- Obstructive Sleep Apnea, Alzheimer Disease, Vascular Dementia, Mild Cognitive Impairment
- Trial name
- ENCHANT (NCT04335994)
- Testing
- In-laboratory polysomnography, Home Sleep Apnea Test
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke, Cognitive Impairment
The Treatment Effectiveness of Combined tDCs and Neurofeedback (NF) for Patients With Cognitive Deficits After Stroke
This is a double blinded, randomized control trial with a pretest-posttest control and interventional groups design. Both the assessor and participants are blinded to all assessments and evaluations.
- Trial name
- NCT03093142
- Testing
- tDCS & neurofeedback, neurofeedback
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Kowloon Hospital, Hong Kong
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder
Study of Cognition and Control in Youths
The purpose of this study is to learn more about the functioning of particular types of regions of the brain, specifically, those related to externalizing disorders such as Attention Deficit Hyperactivity Disorder (ADHD)…
- Conditions
- Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder
- Trial name
- NCT03393390
- Testing
- Clinical Assessment Visit, fMRI scan
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Patient With Bipolar Disorder, Euthymic Status
Cognitive Remediation on Patients With Bipolar Disorder and Memory Complaints
Bipolar disorder is a major health concern. Intercritical periods are marked with residual symptoms, both thymic and cognitive, which affects quality of life of patients, but also the quality of observance.
- Conditions
- Patient With Bipolar Disorder, Euthymic Status, Wirh Memory Complaints
- Trial name
- COGMED (NCT02988518)
- Testing
- COGMED program
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Montpellier
Cognitive Change
COgnitive Dynamics in Early Childhood
The goal of this accelerated longitudinal observational cohort study is to advance our understanding of cognitive variability in children aged 7 to 10 at first measurement.
- Trial name
- CODEC (NCT06330090)
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Psychosis
EPI-MINN: Targeting Cognition and Motivation
The purpose of this study is to perform a practice-based research project designed to assess whether cognition and motivated behavior in early psychosis can be addressed as key treatment goals within real-world settings by using…
- Trial name
- NCT05112432
- Testing
- Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota
Mental Health Wellness, Cognitive Function
Children to Adults Mental and Psychosomatic Health Study (CAMPS)
This study titled the Children to Adults Mental and Psychosomatic Health Study (CAMPS), aims to explore the interplay between mental health, psychosomatic factors, and adverse childhood experiences (ACE) across a broad age range…
- Conditions
- Mental Health Wellness, Cognitive Function, Physical Symptoms
- Trial name
- NCT05621278
- Where
- China
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Healthy Volunteers
Short-Term Rhodiola Rosea for Anaerobic Performance and Cognitive Function in Resistance-Trained Adults
This study will evaluate whether 7 days of Rhodiola rosea (golden root) supplementation can improve resistance-exercise performance and cognitive function in resistance-trained men and women.
- Trial name
- NCT07225413
- Testing
- Rhodiola rosea (low dose), Rhodiola rosea (high dose)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Jacksonville State University
Cardiovascular Diseases, Heart Diseases
New CVD Risk Factors for Lowered Cognitive Functioning
To explore the associations between cognitive functioning and three major cardiovascular disease risk factors: high blood pressure; high total plasma homocysteine (tHcy); and ApoE e4 genotype.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Neurologic Manifestations
- Trial name
- NCT00037310
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Communication Aids for Disabled, Communication Disorders
Outcomes of ICT Assistive Technology in RehabiliTAtIoN Pathways
The study aims to improve the quality of prosthetic intervention and verify the adequacy of assistive devices, and measurement outcomes.
- Conditions
- Communication Aids for Disabled, Communication Disorders, Motor Disorders, Cognitive Disorder
- Trial name
- ATTAIN (NCT06546813)
- Testing
- scales and questionnaire administration
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Coronary Artery Disease
Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia
There are many reports about the association of coronary artery disease (CAD) and cerebral artery stenosis (CAS), which had been proved to induce stroke and cognition decline after the revascularization including coronary bypass…
- Conditions
- Stroke, Coronary Artery Disease, Arrhythmia
- Trial name
- NCT00247533
- Testing
- Digital subtraction angiography and 24-hour simultaneous recorder of electrocardiograph
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Pseudohypoparathyroidism Type 1A, Albright Hereditary Osteodystrophy
Albright Hereditary Osteodystrophy: Natural History, Growth, and Cognitive/Behavioral Assessments
We, the researchers, are following the natural history of Albright hereditary osteodystrophy. We have found that growth hormone deficiency is very common in patients with pseudohypoparathyroidism type 1A, which falls under the…
- Conditions
- Pseudohypoparathyroidism Type 1A, Albright Hereditary Osteodystrophy, Pseudopseudohypoparathyroidism
- Trial name
- NCT00209235
- Testing
- Neurocognitive and psychosocial testing
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Connecticut Children's Medical Center
Physical Activity, Health-related Fitness
Home-Based Exergaming Intervention
This study will employ a 3-arm randomized clinical trial to determine the effects of a 6-month home-based exergaming intervention on preschoolers' physical activity, health-related fitness, cognition, and screen time, across…
- Conditions
- Physical Activity, Health-related Fitness, Cognition, Screen Time
- Trial name
- NCT04540523
- Testing
- Exergaming intervention group, Traditional physical activity comparison
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Duarte Galactosemia
Intervention and Outcomes in Duarte Galactosemia
The purpose of this study is to learn about Duarte galactosemia (DG). This study will examine the possible effects of Duarte galactosemia (DG) in children, and determine whether dietary exposure to milk in infancy or early…
- Trial name
- NCT02519504
- Where
- United States
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Emory University
Dwarfism, Turner's Syndrome
The Effects of Hormones in Growth Hormone-Treated Girls With Turner Syndrome
Turners Syndrome is a genetic condition in females that is a result of abnormal chromosomes. Patients with Turner syndrome are typically short, have abnormal physical features, and lack the physical changes normally associated…
- Trial name
- NCT00001343
- Testing
- Humatrope, Oxandrolone
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Huntington's Disease
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable…
- Trial name
- HDClarity (NCT02855476)
- Where
- 40 sites in United States, Canada and 8 more
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University College, London
Substance Abuse Disorder
To Assess the Effectiveness of Structured Occupational Therapy (OT) Interventions on Patients With SUD in Inpatient Department (IPD) Settings, Focusing on Improvements in Cognitive, Physical, and Functional Domains
OT emphasis lies within the scope of improving daily life activities, cognitive and physical performance in order to regain the proper social role.
- Trial name
- NCT06809504
- Testing
- Exercise based intervention
- Where
- Pakistan
- Volunteers
- 12 people
- Sponsor
- Hammad Mursaleen
Developmental Coordination Disorder (DCD)
Effects of Exercise Combined With Cognitive Training on Motor Performance in Children With Developmental Coordination Disorder
Background: Developmental Coordination Disorder(DCD) is a common neuro-developmental disorder in childhood, characterized by deficits in motor coordination.
- Trial name
- NCT07813052
- Testing
- Combined exercise-cognitive training, Exercise-only training
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai University of Sport
Cognitive Function, Functional Status
Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0
Implementing a Skills-Based Caregiver Training (Caregivers FIRST): Function QUERI 2.0 aims to compare implementation strategies for large-scale spread of Caregivers FIRST, a group training for friend or family caregivers of…
- Trial name
- NCT05319535
- Testing
- Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Moyamoya Disease, Moyamoya Syndrome
Development and Validation of Risk Prediction Models for Stroke and Cognitive Impairment in Moyamoya Disease and Moyamoya Syndrome
This multicenter prospective observational cohort study aims to develop and validate individualized risk prediction models for stroke and cognitive decline in patients with moyamoya disease or moyamoya syndrome by integrating…
- Trial name
- NCT07894107
- Where
- 13 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Tiantan Hospital
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