Clinical trials: Cognitive Functions
Cognitive Development
Testing Whether a Short Training Program Designed to Improve Cognitive Skills Improves 4-year-olds' Maths Skills
This study will test whether a short training program - designed to improve memory and attention skills - will benefit mathematical reasoning in preschoolers from a range of socio-economic backgrounds.
- Trial name
- NCT03063411
- Testing
- Executive Function Intervention, Active Control Group
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
MYT1L Syndrome
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder
MYT1L syndrome is a rare genetic syndrome, recently described in 2011, with paediatric onset, responsible for a neurodevelopmental disorder combining psychomotor retardation, learning difficulties and/or intellectual development…
- Trial name
- MYT1L (NCT07008612)
- Testing
- Patients with a genetic syndrome linked to the MYT1L gene, Patients with a neurodevelopmental disorder of genetic origin but not linked to MYT1L
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Rouen
Sedentary Behavior;Cognition;Cardiovascular-related Disease
Prospective Cohort Study on Cognition and Cardiovascular Disease of Sedentary Behaviors in Children
The prospective cohort study is set up to address research questions dealing with sedentary lifestyle-related events mainly including cognition and cardiovascular-related disease in children .Participants aged 7-12 years old from…
- Trial name
- NCT03582709
- Volunteers
- 1,000 people
- Sponsor
- CHEN Yajun
Craniofacial Microsomia, Hemifacial Microsomia
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
This study is a multi-center, longitudinal cohort study of 125 infants with craniofacial microsomia (CFM) and 100 infants without craniofacial anomalies.
- Conditions
- Craniofacial Microsomia, Hemifacial Microsomia, Oculo-Auriculo-Vertebral-Syndrome, Goldenhar Syndrome
- Trial name
- CLOCK (NCT02224677)
- Where
- 5 sites in United States
- Volunteers
- 417 people
- Sponsor
- Seattle Children's Hospital
Autism
Treatment for Children With Autism and Anxiety
Children with high-functioning autism spectrum disorders (ASD) are at high risk for developing significant anxiety symptoms. Cognitive behavior therapies (CBT) are frequently used for children with anxiety symptoms with good…
- Trial name
- NCT01727466
- Testing
- Facing Your Fears
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Cognitive Impairment
Detection of AD Biomarkers in Tear Fluid
Detection of AD biomarkers in tear fluid
- Trial name
- SmartTears (NCT04620902)
- Testing
- Tear sampling
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Irritable Bowel Syndrome
Internet-delivered Exposure-based Cognitive Behavior Therapy for Irritable Bowel Syndrome - a Cohort Effectiveness Study
The main purpose of the study is to investigate the clinical real-world effectiveness of a specific exposure based psychological treatment for irritable bowel syndrome (IBS).
- Trial name
- NCT05328245
- Volunteers
- 319 people
- Sponsor
- Karolinska Institutet
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
Tau/P-Tau and Neurocognitive Outcomes in Children
The proposed studies are aimed to measure Tau and P-Tau levels in pre- and postoperative blood, urine, feces and saliva, as well as to assess pre- and postoperative neurocognitive function in children (3 to 5 years old) who will…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
- Trial name
- NCT03511729
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia
Cognitive Enhancement Therapy for Early-Stage Schizophrenia
This study will determine the effectiveness of cognitive enhancement therapy (CET) in treating cognitive abnormalities in people experiencing the early stages of schizophrenia.
- Trial name
- NCT00167362
- Testing
- Cognitive enhancement therapy (CET), Enriched supportive therapy (EST)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Intellectual Disability, Mild
Effects of a 12-Week Pickleball Training Program on Cognitive and Motor Skills in Adolescents With Mild Intellectual Disability
This study aims to investigate the effects of a 12-week pickleball training program on cognitive and motor outcomes in adolescents with mild intellectual disability.
- Trial name
- PBID-12 (NCT07586722)
- Testing
- Pickleball Training Intervention Group, Standard Special Education Curriculum
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Elif Top
Mood Behaviour, Cognitive Function
The Impact of Milk-products Differing in Their Glycaemic Properties on the Behaviour of Infants
The current study proposes to investigate the impact of a low glycaemic index (GI), fortified toddlers milkpowder on mood, behaviour and cognitive function in young children.
- Trial name
- NCT01589003
- Testing
- Low Glycaemic index growing up milk, High GI growing up milk
- Where
- Malaysia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Geok Lin Khor
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Transcranial Direct Current Stimulation in Children With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06880159
- Testing
- tDCS with computerized cognitive training
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Parkinson Disease, Executive Dysfunction
Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease
The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.
- Trial name
- NCT03285347
- Testing
- Computer-based cognitive training
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: Is brain development different in JoHD than Adult-onset…
- Trial name
- NCT05707663
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Iowa
Attention-Deficit/Hyperactivity Disorder (ADHD)
Occupational Therapy-Based Dance Program for Children With ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition that can affect children's attention, movement, balance, sensory processing, and self-esteem.
- Trial name
- OTDANCE-ADHD (NCT07731893)
- Testing
- Occupational Therapy-Based Dance Program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- IREM CEYHAN
Attention Deficit Hyperactivity Disorder (ADHD), ADHD
Effects of Phosphatidylserine and DHA on Cognitive Performance in Children With ADHD
This study aimed to evaluate the effects of different phosphatidylserine (PS) formulations, with or without docosahexaenoic acid (DHA), on cognitive performance in children diagnosed with attention-deficit/hyperactivity disorder…
- Trial name
- PS-DHA-ADHD (NCT07521449)
- Testing
- Phosphatidylserine-Omega3, DHA Omega-3
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Çağlar Charles Daniel Jaicks
Depressive Disorder
Effects of Non-drug Therapy on Cognitive Function in Healthy Individuals and Patients With First Episode Depression
Mindfulness training, relaxation training, and cerebellar electrical stimulation were used to intervene in the cognitive function of healthy individuals and individuals with first episode depression
- Trial name
- NCT04503343
- Testing
- non-drug intervention
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Central South University
Cardiac Surgery, Postoperative Cognitive Dysfunction
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery
- Conditions
- Cardiac Surgery, Postoperative Cognitive Dysfunction, Neurologic Manifestations
- Trial name
- NCT06655025
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Obesity, Physical Fitness
Comprehensive Versus Traditional Lifestyle Program
Despite recommends that school-based interventions use a comprehensive approach for health promotions; most fitness programs exclusively emphasize physical activity.
- Conditions
- Obesity, Physical Fitness, Cognitive Function 1, Social
- Trial name
- NCT03182621
- Testing
- THINK, SPARK
- Volunteers
- 105 people
- Sponsor
- University of Miami