Clinical trials: Collaboration
Chordoma
Genetic Aspects of Chordoma: A Collaboration With SEER Registries to Identify Chordoma Families
Chordoma is an uncommon (400 case/year in the U.S.) and potentially fatal bone tumor derived from remnants of embryonic notochord.
- Trial name
- NCT00341627
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- National Cancer Institute (NCI)
Leukemia
International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia
Rationale/Purpose: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT01117441
- Testing
- PEG-L-asparaginase, cyclophosphamide, cytarabine
- Where
- 139 sites in Australia, Austria and 5 more
- Volunteers
- 6,136 people
- Sponsor
- University Hospital Schleswig-Holstein
Asthma in Children
The Duke-Reinvestment Partners Community Collaborative (DRC)- Healthy Homes
The goal of this open-label, single arm home intervention feasibility study is to improve quality of life for children ages 4-16 years with asthma.
- Trial name
- DRC (NCT05934370)
- Testing
- Home-Based Environmental Interventions (HEI)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Duke University
Stress
Early Interventions for Primary Care Patients With Stress-related Ill-health: a Non-inferiority RCT
Stress-related ill-health is rated one of the largest health challenges in the western world. The most empirically supported treatment for stress-related disorders is cognitive behaviour therapy (CBT), but accessibility is low…
- Trial name
- NCT04820283
- Testing
- Care manager intervention (nurse), CBT
- Where
- Sweden
- Volunteers
- 172 people
- Sponsor
- Karolinska Institutet
Child Health
Partnering for Change in Sweden - Intervention to Increase Pupils' Engagement and Participation
This project implements an innovative and intersectional collaborative intervention model that addresses challenges that exist for children with special educational needs, who risk school failure, exclusion and poor health.
- Trial name
- NCT05435937
- Testing
- Partnering for change (P4C-Swe), Treatment as usual
- Where
- 3 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Linkoeping University
Leukemia
Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00015873
- Testing
- asparaginase, cytarabine, mercaptopurine
- Where
- 33 sites in United States, Austria and 9 more
- Volunteers
- 350 people
- Sponsor
- Dutch Childhood Oncology Group
Education, Asthma
Evaluating the Collaborative Management in Pediatrics (CMP) Training Program Among Pediatric Resident Doctors and Their Patients With Asthma or Obesity
Self-care behaviors are decisions and actions that people can take to improve their health or cope with a health problem. It is important for people with long-term illnesses to develop and maintain effective self-care behaviors.
- Conditions
- Education, Asthma, Obesity
- Trial name
- CMP (NCT00510341)
- Testing
- Collaborative Management in Pediatrics (CMP) Program
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Washington
Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
This study is a treatment protocol with blinatumomab for infants under 1 year old who are diagnosed with acute lymphoblastic leukemia with a specific unfavorable genetic alteration.
- Trial name
- Interfant-21 (NCT05327894)
- Testing
- Blinatumomab
- Where
- 124 sites in Argentina, Australia and 22 more
- Volunteers
- 160 people
- Sponsor
- Princess Maxima Center for Pediatric Oncology
Interprofessional Relations, Interprofessional Education
Interprofessional Collaboration in the Cardiac Intensive Care Unit (CICU): An Action-Research Training Project
This study evaluates the impact of a structured interprofessional training program on daily collaboration within the Cardiac Intensive Care Unit (CICU/UTIC) at the University Hospital of Parma.
- Conditions
- Interprofessional Relations, Interprofessional Education, Attitude of Health Personnel, Intensive Care Units
- Trial name
- COLLUTIC_25 (NCT07360366)
- Testing
- The training phase of the project consists of an interactive course aimed at healthcare professionals (physicians, nurses and OSS) to improve their ability to recognise and enact effective collaborati
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Leukemia
Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00967057
- Testing
- asparaginase, dexamethasone, idarubicin
- Where
- 6 sites in Australia, United Kingdom
- Volunteers
- 470 people
- Sponsor
- Children's Cancer and Leukaemia Group
Mental Disorder, Depression
Screening to Identify Parents in Need of Mental Health Support: A Feasibility Study in Child Welfare Services
The main aim of this study is to evaluate the feasibility, preliminary effects and experiences of the Collaboration-Screening-Referral approach (CSR / in Swedish: Samverkan-Screening-Hänvisning - SSH) when used with parents…
- Conditions
- Mental Disorder, Depression, Anxiety, Child Abuse
- Trial name
- NCT06600139
- Testing
- The Collaboration-Screening-Referral (SSH) model
- Where
- Sweden
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Parent-Child Relations, Parenting
National Evaluation of the Close Collaboration With Parents Training
The aim of this study was to evaluate the effects of an educational intervention for neonatal staff on parent-infant physical closeness during their infant's stay in the Neonatal Intensive Care Unit (NICU) and parents' and staff…
- Conditions
- Parent-Child Relations, Parenting, Infant, Newborn, Disease
- Trial name
- VVME5 (NCT04635150)
- Testing
- Close Collaboration with Parents
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Turner's Syndrome
Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years
The objective of this study is to evaluate the efficacy and safety of recombinant human growth hormone (r-hGH) treatment in girls with Turner Syndrome under the age of 4 years.
- Trial name
- NCT01066052
- Testing
- r-hGH
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Malaria
Artemisinin Resistance In Malaria Treated With IV Artesunate
The spread of artemisinin resistant falciparum malaria presents new challenges to both the control and treatment of malaria. Loss of ring stage susceptibility to the artemisinins might jeopardize the use of parenteral artesunate…
- Trial name
- ARIMTIA (NCT02640495)
- Testing
- Intravenous Artesunate as part of standard medical practice
- Sponsor
- University of Oxford
Integrated Care, Telehealth
Regional Implementation of Collaborative Lung Function Testing
Background/Aims There is evidence indicating that deployment of forced spirometry (FS) testing in a collaborative scenario, encompassing respiratory specialists and community professionals, generates healthcare efficiencies.
- Conditions
- Integrated Care, Telehealth, Health Care Rationing
- Trial name
- e-Spiro-HC3 (NCT02592928)
- Testing
- Inclusion of Spirometry into the Electronic Health Records
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Clinic of Barcelona
Coronavirus Infection
Community Collaboration to Combat COVID-19 (C-FORWARD)
This is randomized trial where households will be randomized to identify the optimal SARS-CoV-2 (COVID-19) testing modality in a population-representative sample of households in Baltimore City, Maryland.
- Trial name
- NCT04673292
- Testing
- Fixed site standard of care testing, Community-based, mobile van testing, Self-collected, home-based testing
- Where
- United States
- Volunteers
- 831 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV Infections
A Continued Access Study for Participants Transitioning From ViiV Healthcare-sponsored or ViiV Healthcare-collaborative Parent Studies for HIV Treatment
The purpose of this study is to provide continued access to the study treatment for participants from previous ViiV Healthcare studies who are still benefiting from it and do not have local access after completing the parent…
- Trial name
- PATH (NCT07393659)
- Testing
- Fostemsavir, Dolutegravir (DTG)/ Lamivudine (3TC)
- Where
- 4 sites in South Africa
- Volunteers
- 181 people
- Sponsor
- ViiV Healthcare
Scoliosis Idiopathic, Scoliosis; Juvenile
Ultrasound for Scoliosis Diagnostic Evaluation
Scoliosis is a complex 3-dimensional deformity of the spine. It may occur at any time throughout growth and development and is typically detected through x-ray imaging.
- Trial name
- NCT03222739
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's National Research Institute
Acquired Thrombotic Thrombocytopenic Purpura
Improvement of Immunologic and Molecular Techniques for the Diagnosis and Follow-up of Patients With Thrombotic Thrombocytopenic Purpura
The lack of ADAMTS13 is the only biological marker that is specific for aTTP diagnosis8 and the assessment of ADAMTS13 is of clinical importance because it is essential for the rapid differential diagnosis between aTTP and other…
- Trial name
- NCT05046717
- Testing
- ADAMTS13 Activity Assays
- Where
- 6 sites in Portugal, Spain
- Volunteers
- 500 people
- Sponsor
- Fundación Española de Hematología y Hemoterapía
Nurse Training
Integrating Design Thinking Into Undergraduate Nursing Education
Previous studies have demonstrated that design thinking workshops can indeed produce these effects in healthcare education settings. However, its effectiveness in nursing curriculum is inconclusive.
- Trial name
- NCT06673316
- Testing
- Design thinking workshop
- Where
- Hong Kong
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong