Clinical trials: Collaboration
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00019864
- Testing
- filgrastim, cisplatin, dexrazoxane hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Overuse Injury
Throwing Device Tracker for Youth Injury Prevention
The primary objective of this study is to collect motion-capture data on movements common to baseball play in order to develop an algorithm for a wearable device for the prevention and rehabilitation of sports-related overuse…
- Trial name
- NCT04098107
- Testing
- Throwing Device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cystic Fibrosis, Patient Engagement
Cystic Fibrosis Reproductive and Sexual Health Collaborative: Building Online Research Partnerships
This is a Patient-Centered Outcomes Research Institute engagement effort aimed at training researchers/providers and patients to work in research teams together online throughout the research process (including: development…
- Trial name
- NCT04999865
- Testing
- 4-part educational program to build patient-engagement methodology capacity
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Rheumatic Fever, Rheumatic Heart Disease in Children
ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months.
The ACT4RHD trial is a multicentre, pragmatic, multi-arm, open-label adaptive platform trial addressing multiple therapeutic questions in patients with ARF and carditis.
- Conditions
- Rheumatic Fever, Rheumatic Heart Disease in Children, Acute Rheumatic Fever, Rheumatic Heart Disease
- Trial name
- ACT4RHD (NCT07830108)
- Testing
- Hydroxychloroquine (HCQ), No Hydroxychloroquine (HCQ), Prednisone or Prednisolone
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 600 people
- Sponsor
- Starship Child Health, Te Toka Tumai Auckland
Familial Hypercholesterolemia
EAS Familial Hypercholesterolaemia Studies Collaboration
Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C).
- Trial name
- FHSC (NCT04272697)
- Where
- United Kingdom
- Volunteers
- 75,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Myopia
The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda…
- Trial name
- NCT00000169
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
GRADE Approach, Summary of Findings Table
New Alternative Formats vs Standard of SoF Tables. Non-inferiority Controlled Trial
The investigators will conduct a parallel two-armed, non-inferiority randomized trial comparing new alternative formats of summary of findings tables (SoF) tables with current formats.
- Conditions
- GRADE Approach, Summary of Findings Table, Cochrane Collaboration
- Trial name
- NCT02022631
- Testing
- Alternative summary of findings table format, Current summary of findings table format
- Where
- Canada
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- McMaster University
Parent-Child Relations, Parenting
National Evaluation of the Close Collaboration With Parents Training
The aim of this study was to evaluate the effects of an educational intervention for neonatal staff on parent-infant physical closeness during their infant's stay in the Neonatal Intensive Care Unit (NICU) and parents' and staff…
- Conditions
- Parent-Child Relations, Parenting, Infant, Newborn, Disease
- Trial name
- VVME5 (NCT04635150)
- Testing
- Close Collaboration with Parents
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sickle Cell Disease, Multiple Myeloma
ASH Research Collaborative Data Hub
Benign and malignant hematologic diseases are relatively rare conditions within the spectrum of medical practice in any one site of care.
- Trial name
- NCT05775224
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- ASH Research Collaborative
HPV, Stigma
Actions For Collaborative Community Engaged Strategies for HPV
In the current pilot study, Actions for Collaborative Community-Engaged Strategies for HPV (ACCESS-HPV), investigators will use participatory crowdsourcing methods to drive HPV prevention among mother-daughter dyads.
- Trial name
- NCT06010108
- Testing
- Heroes for Her, The Reach Initiative, W.H.I.T.E project
- Where
- Nigeria
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Child Abuse, Child Neglect
Children at Risk and Oral Health, The Dental Record Study
The objectives of this retrospective dental record study, are to increase knowledge of the oral health, - history and -needs of children enrolled at the Childrens Advocacy Centers (CAC)by: assessing if it is possible to identify…
- Conditions
- Child Abuse, Child Neglect, Child Maltreatment
- Trial name
- NCT05772962
- Where
- Norway
- Volunteers
- 2,400 people
- Sponsor
- Oral Health Centre of Expertise in Western Norway
Influenza, Collaboration
Collaborative Efforts to Increase Flu Vaccination
Beginning with the 2009-2010 season, influenza vaccine is universally recommended for children age 6 months to 18 years old, placing extra burden on health care providers across the U.S.
- Trial name
- CollabFlu (NCT01403649)
- Testing
- Private/public collaboration to increase flu vaccination, Usual care
- Where
- 27 sites in United States
- Volunteers
- 117,175 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
X-Linked Hypophosphatemia
Study of Longitudinal Observation for Patient With X-linked Hypophosphatemic Rickets/Osteomalacia in Collaboration With Asian Partners
Through observation of patients with X-linked hypophosphatemic rickets/osteomalacia (XLH) for up to 10 years, the study intends to collect data that allow achievement of the following objectives: 1.
- Trial name
- SUNFLOWER (NCT03745521)
- Testing
- no intervention
- Where
- Japan
- Volunteers
- 226 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Chordoma
Chordoma Family Study
This pilot study, conducted by the National Cancer Institute and the Massachusetts General Hospital, will investigate genetic factors that contribute to the development of chordoma in people from some families.
- Trial name
- NCT00410670
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Heart Failure
Collaborative Systematic Overview of Randomised Controlled Trials of Beta-Blockers in the Treatment of Heart Failure
Several large trials have shown that beta-blocker treatment reduces the risk of death and hospital admission in patients with symptomatic heart failure.
- Trial name
- BB-META-HF (NCT00832442)
- Testing
- Beta blocker
- Where
- 2 sites in United Kingdom
- Volunteers
- 18,240 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Depression, Anxiety
The CARE (Collaborative Adolescent Running Experience) Project
This study is being completed to see if participants activity levels may have an impact as a treatment for depression, or depressive symptoms.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Bipolar Disorder
- Trial name
- CARE (NCT05837351)
- Testing
- Exercise -Running
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Child Behavior, Problem Behavior
Executive Function and Symptom Reduction in Youth Receiving Home-based Treatment With Collaborative Problem Solving
In this project, the investigators will extend prior results of parent-reported executive function growth and symptom reduction in children receiving home-based treatment with the Collaborative Problem Solving treatment approach…
- Conditions
- Child Behavior, Problem Behavior, Executive Dysfunction
- Trial name
- NCT04121650
- Testing
- Collaborative Problem Solving
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Nurse
Physician-Nurse and Nurse-Nurse Collaboration
This study was carried out to determine the level of collaboration and the factors affecting its between physicians-nurses and nurses-nurses working in different hospitals.
- Trial name
- NCT03835247
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ordu University
Transposition of Great Vessels
Comprehensive Long-term Follow up of Adults With Arterial Switch Operation
Background: Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively…
- Trial name
- EPOCH-ASO (NCT04335448)
- Testing
- No intervention is planed
- Where
- 11 sites in Austria, France and 3 more
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Congenital Diaphragmatic Hernia
De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
The purpose of this study is to determine if de-implementation of inhaled nitric oxide (iNO) in the post-natal resuscitation/stabilization phase affects the composite outcome of extracorporeal life support (ECLS) use and/or…
- Trial name
- NCT05213676
- Testing
- Inhaled Nitric Oxide (iNO) use, De-implementation of Inhaled Nitric Oxide (iNO) use
- Where
- 19 sites in United States
- Volunteers
- 900 people
- Sponsor
- The University of Texas Health Science Center, Houston