Clinical trials: Collaboration
Prematurity, Necrotizing Enterocolitis
Collaborative Research Group for Necrotizing Enterocolitis
This proposal will test the hypothesis that synthesis and catabolism of epidermal growth factor (EGF), the genotype of the EGF gene, and the microbiome interact to influence EGF expression in infants at risk for necrotizing…
- Trial name
- NCT00828451
- Testing
- [5,5,5-2H3]leucine (stable isotope labeled leucine)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Washington University School of Medicine
Hematopoietic Stem Cell Transplantation, Art Therapy
Art and Physical Therapy in Pediatric HCT
The purpose of this study is to compare the effect of a combination of art therapy (AT) and physical therapy (PT) to PT only in children undergoing hematopoietic cell transplant (HCT).
- Conditions
- Hematopoietic Stem Cell Transplantation, Art Therapy, Physical Therapy
- Trial name
- NCT05441670
- Testing
- Art and Physical Therapy, Physical Therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Medical University of South Carolina
Collaboration Attitudes and Behavior
Innovation Labs to Enhance Collaboration
Conduct and evaluate the impact of two week-long Innovation Labs on collaboration attitudes and behavior among early career scholars.
- Trial name
- NCT05395286
- Testing
- Innovation Lab
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Traumatic Brain Injury
CENTER-TBI: Collaborative European NeuroTrauma Effectiveness Research in TBI
The research aims of the CENTER-TBI study are to: 1. better characterize Traumatic Brain Injury (TBI) as a disease and describe it in a European context, and 2. identify the most effective clinical interventions for managing TBI.
- Trial name
- CENTER-TBI (NCT02210221)
- Where
- 65 sites in Austria, Belgium and 17 more
- Volunteers
- 4,559 people
- Sponsor
- University Hospital, Antwerp
Asthma
RVA Breathes: A Richmond City Collaboration to Reduce Pediatric Asthma Disparities
The goal of this study is to evaluate a sustainable, community-engaged program to reduce asthma disparities among 5 to 11-year-old children in Richmond, Virginia.
- Trial name
- NCT03297645
- Testing
- School, Asthma education, Home environmental remediation
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Virginia Commonwealth University
Adherence, Patient, Pre-Exposure Prophylaxis
mHealth Technologies to Enhance PrEP Adherence Among Thai MSM
This study aims to: 1) adapt the theory-based P3 (Prepared, Protected, emPowered) app designed to improve pre-exposure prophylaxis (PrEP) adherence, retention in PrEP clinical care, and PrEP persistence among young gay, bisexual…
- Conditions
- Adherence, Patient, Pre-Exposure Prophylaxis, HIV/AIDS
- Trial name
- P3-T (NCT04413708)
- Testing
- P3-T PrEP Adherence App
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Pulmonary Embolism, Venous Thromboembolism
Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use
The researchers hypothesize that existing-prescription notifications directed to pharmacists are more likely to lead to a prescription change than existing-prescription notifications directed to prescribers.
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Atrial Fibrillation
- Trial name
- NCT05351749
- Testing
- New-prescription Alert, New-prescription Alert with referral option, Existing-prescription notification to prescriber
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- University of Michigan
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spina Bifida, Kidney Transplant
Urological and Renal Disease Engaging Adolescents in Adherence Collaborative Trial
The purpose of this study is to determine the effectiveness of behavioral feedback plus economic incentives to promote treatment adherence among a large diverse population of adolescents and young adults (AYA) with kidney…
- Trial name
- U-REAACT (NCT03045276)
- Testing
- Behavioral Feedback and Economic Incentives: Arm 1, Behavioral Feedback and Economic Incentives: Arm 2
- Where
- 6 sites in United States
- Volunteers
- 465 people
- Sponsor
- Children's Hospital of Philadelphia
Troponin, Age
NIHR CV Health Informatics Collaborative
The National Institute for Health Research (NIHR) Cardiovascular Health Informatics Collaborative is an observational, multi-centre and longitudinal study of clinical data from collaborating hospitals.
- Conditions
- Troponin, Age, Mortality, Acute Coronary Syndrome
- Trial name
- NHIC-CV (NCT03507309)
- Volunteers
- 257,948 people
- Sponsor
- Imperial College London
Medically Complex Children, Care Coordination
Improving Care for Children With Complex Needs
Seattle Children's Hospital (SCH), in collaboration with several health plans and Washington State Department of Social and Health Services developed the Comprehensive Case Management (CCM) program with the goal to reduce costs…
- Conditions
- Medically Complex Children, Care Coordination, Case Manager, Care Manager
- Trial name
- I3CN (NCT01587105)
- Testing
- Comprehensive Case Management Service
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Seattle Children's Hospital
Turner's Syndrome
Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years
The objective of this study is to evaluate the efficacy and safety of recombinant human growth hormone (r-hGH) treatment in girls with Turner Syndrome under the age of 4 years.
- Trial name
- NCT01066052
- Testing
- r-hGH
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Coronavirus Infection
Community Collaboration to Combat COVID-19 (C-FORWARD)
This is randomized trial where households will be randomized to identify the optimal SARS-CoV-2 (COVID-19) testing modality in a population-representative sample of households in Baltimore City, Maryland.
- Trial name
- NCT04673292
- Testing
- Fixed site standard of care testing, Community-based, mobile van testing, Self-collected, home-based testing
- Where
- United States
- Volunteers
- 831 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dental Pulp Exposure
Pulp Capping With Two Different Agents
The purpose of this study is to determine if MTA or calcium hydroxide are more effective as pulp capping agents
- Trial name
- MTA (NCT00812877)
- Testing
- Mineral Trioxide Aggregate, Calcium Hydroxide
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Food Hypersensitivity
Oral Immunotherapy for Peanut Allergy (PMIT)
The purpose of this study is to determine if mucosal peanut immunotherapy will make subjects who have peanut allergy less allergic and induce changes in their immune system.
- Trial name
- PMIT (NCT00597675)
- Testing
- Peanut OIT
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Post-traumatic Stress Disorder, Alcohol Abuse
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Recent needs assessments suggest that difficulties exist in care coordination between emergency medical services (EMS) systems and primary care for injured adolescents with alcohol problems and post-traumatic stress disorder…
- Conditions
- Post-traumatic Stress Disorder, Alcohol Abuse, Alcohol Dependence
- Trial name
- ATRSCC (NCT00619255)
- Testing
- Adolescent Trauma Support Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Opioid Dependence
Dane County Drug Court Study for Addicted Offenders
The proposed work addresses critical health and public safety issues in the U.S. and in Wisconsin: the intersection of addiction and crime and the prevention of associated individual and public health complications.
- Trial name
- NCT01843751
- Testing
- buprenorphine/naloxone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Overuse Injury
Throwing Device Tracker for Youth Injury Prevention
The primary objective of this study is to collect motion-capture data on movements common to baseball play in order to develop an algorithm for a wearable device for the prevention and rehabilitation of sports-related overuse…
- Trial name
- NCT04098107
- Testing
- Throwing Device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Leukemia, Myelocytic, Acute
Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
The purpose of this study is to compare the effectiveness of two multi-agent chemotherapy regimens using different dosages of cytarabine to eliminate all detectable leukemia.
- Trial name
- NCT00136084
- Testing
- Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone, Etoposide, Cytarabine, Gemtuzumab, L-asparaginase, Mercaptopurine, methotrexate, Mitoxantrone, Prednisone, Vincristine
- Where
- 8 sites in United States
- Volunteers
- 238 people
- Sponsor
- St. Jude Children's Research Hospital
Hydration, Dental Caries
Healthy Hydration Pilot in Elementary Schools
This study will pilot a school-based stakeholder-informed hydration intervention and examine its feasibility and preliminary efficacy.
- Conditions
- Hydration, Dental Caries, Body Mass Index
- Trial name
- NCT06132763
- Testing
- Hydration Intervention, Control - Assessments Only
- Where
- United States
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University