Clinical trials: Colon, Sigmoid
Cancer of Rectum
Peritoneal Microdialysis in Patients Undergoing Low Anterior Resection (LAR) for Recto-sigmoid Cancer
Anastomotic leakage is a serious complication after LAR with high morbidity and mortality rates. Early diagnosis and treatment is mandatory.
- Trial name
- NCT00271986
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Sigmoid Volvulus
Sigmoid Colon Volvulus in Sohag
The primary goal of this study observational is to highlight the paradigm of sigmoid colon volvulus as a cause of large intestinal obstruction in young age groups in addition to the elderly for early diagnosis and thus avoiding…
- Trial name
- NCT07170410
- Volunteers
- 40 people
- Sponsor
- Sohag University
Inflammatory Bowel Diseases, Proctosigmoiditis
Role of FCI in the Detection of Proctosigmoiditis Caused by IBD
The goal of this pilot study is to explore the ability of field-cycling imaging, a new scanning technology being developed at the University of Aberdeen, to detect active disease in patients with proctosigmoiditis caused by…
- Trial name
- ROOFTOPS-IBD (NCT05817266)
- Testing
- Field-cycling imaging (FCI)
- Where
- United Kingdom
- Sponsor
- NHS Grampian
Incarcerated Inguinal Hernia
Incarcerated Right Inguinal Hernia Containing Sigmoid Colon: An Unusual Case Report
Incarcerated inguinal hernia is an irreducible but the blood supply to the contained part is intact, but developing towards strangulation. Here the lumen of the portion of colon occupying a hernia sac is blocked with faeces.
- Trial name
- NCT05251350
- Testing
- surgery
- Where
- Afghanistan
- Volunteers
- 2,717 people
- Sponsor
- Ahmadullah Danish
Intestinal Anastomotic Leak
Risk Factors for Anatomic Leakage in Advanced Ovarian Cancer Surgery
Cytoreductive surgery is currently the main treatment for advanced epithelial ovarian cancer (AEOC), and the complete disease removal (RT=0) or the achievement of an optimal residual disease (RT < 1 cm) remain the factors with…
- Trial name
- NCT04604964
- Testing
- Evaluation of anastomotic leakage occurrence
- Where
- Italy
- Volunteers
- 515 people
- Sponsor
- Catholic University of the Sacred Heart
Mortality, Morbidity
Natural Orifice Specimen Extraction in Sigmoid Volvulus
Sigmoid resection can be performed using conventional and laparoscopic methods. There are few publications in the literature reporting specimen removal from the natural hole in patients with a diagnosis of sigmoid volvulus.
- Trial name
- NCT04740619
- Testing
- Natural Orifice Specimen Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Colorectal Cancer (CRC), Surgery, Colorectal
Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy
This study is a randomized, controlled trial comparing the short- and long-term outcomes of left colonic artery or first sigmoid artery preservation for rectal surgery.
- Conditions
- Colorectal Cancer (CRC), Surgery, Colorectal, Oncology
- Trial name
- COLAP-D3 (NCT06938490)
- Testing
- Anterior rectal resection with D3-lymphatic dissection
- Where
- Russia
- Volunteers
- 778 people
- Sponsor
- the BELOOSTROV Clinic of High Technologies
Colon Polyps
Prospective Study of Colon Serrated Polyps
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions.
- Trial name
- NCT02332785
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Colorectal Neoplasms
Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
Patients with suspected or proven sigmoid colon adenocarcinoma, eligible for curative treatment whose MRI can be reviewed prior to surgery and has no decision regarding radical treatment are eligible.
- Conditions
- Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging
- Trial name
- IMPRESS (NCT02222844)
- Testing
- Preoperative MRI scan
- Where
- 16 sites in United Kingdom
- Volunteers
- 244 people
- Sponsor
- Imperial College London
Food Allergy in Infants, Proctocolitis
Suspicion of Non IgE-mediated Cow's Milk Protein Allergy: Prevalence and Evolution
Cow's milk protein allergy (CMPA) is often evoked in infants, in particular in front of delayed symptoms such as rectal bleeding, atopic dermatitis, excessive crying, reflux, failure to thrive...
- Conditions
- Food Allergy in Infants, Proctocolitis, Atopic Dermatitis, Reflux, Gastroesophageal
- Trial name
- NCT04651829
- Testing
- oral food challenge 1, oral food challenge 2
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital Armand Trousseau
Outcome
Treatment in Right Colon Diverticulitis Patients
The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness.
- Trial name
- NCT04746326
- Testing
- Failure conservative treatment, Surgery, Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Tepecik Training and Research Hospital
Endoscopic Surgical Procedure
Percutaneous Sigmoid Fixation For Management Of Recurrent Sigmoid Volvulus
The investigators included all patients who were presented to emergency department with recurrent sigmoid volvulus at Zagazig University hospital between (August 2024 to August 2025).
- Trial name
- NCT07155304
- Testing
- percutaneous sigmoid colon fixation
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Crohn's Enteritis, Crohn Disease
Physical Fitness Levels in Children and Adolescents With Chronic Inflammatory Bowel Disease (CIBD): Crohn's Disease, Ulcerative Colitis, Chronic Unclassified Colitis
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), ulcerative colitis (UC) and IBD-unclassified (IBD-U), are characterised by chronic inflammation of the gastrointestinal tract.
- Conditions
- Crohn's Enteritis, Crohn Disease, Inflammatory Bowel Diseases, Colitis, Ulcerative
- Trial name
- MICI-FIT (NCT04647578)
- Testing
- GT3X Actigraph accelerometer.
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Pathology, Sigmoid Volvulus
Review of Isolated Hypoganglionosis and Presentation of a New Case Complicated With Sigmoid Volvulus
Isolated hypoganglionosis is rare and constitutes 3-5% of all congenital neurological bowel diseases. Since hypoganglionosis is associated with symptoms such as chronic constipation or pseudo-obstruction, it can be confused with…
- Conditions
- Pathology, Sigmoid Volvulus, Hypoganglionosis
- Trial name
- NCT04363125
- Testing
- Pathology result
- Where
- Turkey (Türkiye)
- Volunteers
- 310 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Perforated Diverticulitis
The Damage Control Strategy for the Treatment of Perforated Diverticulitis of the Sigmoid Colon With Diffuse Peritonitis
The best approach for the treatment of perforated diverticulitis of the sigmoid colon is still under debate. Concurrent techniques are 1) resection with primary colorectal anastomosis with or without additional loop ileostomy; 2)…
- Trial name
- NCT04220840
- Testing
- Damage control strategy
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Städtisches Klinikum München GmbH
Rectal Cancer, Colon Cancer
Learning Curve of SILS in CRC
Based on the data analysis of the General Surgery Department (Northern Department) of Ruijin Hospital from December 2013 to June 2021, we conducted a retrospective cohort study.
- Conditions
- Rectal Cancer, Colon Cancer, Single Port Laparoscopy
- Trial name
- SILS (NCT07736131)
- Volunteers
- 280 people
- Sponsor
- Ruijin Hospital
Lateral Sinus Thrombosis, Mastoiditis
Otogenic CSVT Retrospective Case Series and Associated Thrombophilia
The aim of this study is to report the clinical presentation, Microbiological, laboratory and imaging evaluation, prothrombotic factors analysis, medical and surgical management and outcomes in children with Otogenic Cerebral…
- Conditions
- Lateral Sinus Thrombosis, Mastoiditis, Otitis Media
- Trial name
- CSVT PCR (NCT03864055)
- Where
- Israel
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Pathology
Different Clinicopathological Features of Non-Elderly Sigmoid Volvulus Patients
Sigmoid volvulus is frequently seen in male patients over 60 years old. In the sigmoid volvulus <60 age groups, the male/female ratio is close to each other.
- Trial name
- NCT04360525
- Testing
- Reasons
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Endometriosis
Functional Outcome in Patients That Underwent Laparoscopic Sigmoid and/or Rectum Resection
Questionnaire To assess the functional outcome in patients that underwent laparoscopic sigmoid and/or rectum resection.
- Trial name
- NCT01953250
- Where
- Belgium
- Volunteers
- 143 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colo-rectal Cancer
EMVI as a Determinant of Metastasis in Colorectal Cancer
Bowel cancer is the fourth most commonly occurring cancer and the second highest cause of cancer deaths in the UK. Despite advances in treatment, over 40% of patients will die within 5 years.
- Trial name
- EVIDENCE (NCT06646341)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London