Clinical trials: Colonic Cancer
Colon Cancer, Laparoscopic Colon Surgery
Analysis of Surgical and Oncologic Outcomes After Complete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer
The goal of this observational study is to investigate the efficacy and safety of a modified D3 lymphadenectomy approach compared to Complete Mesocolic Excision (CME) in patients with right-sided colon cancer.
- Conditions
- Colon Cancer, Laparoscopic Colon Surgery, Lymph Node Dissection, Robotic Surgical Procedures
- Trial name
- NCT06684223
- Where
- South Korea
- Volunteers
- 3,787 people
- Sponsor
- Asan Medical Center
Enteropathogenic Escherichia Coli ., Colorectal Carcinoma
Enteropathogenic Escherichia Coli (EPEC): Does it Have a Role in Colorectal Tumourigenesis?
Despite the characterization of many aetiologic genetic changes. The specific causative factors in the development of sporadic colorectal cancer remain unclear.
- Trial name
- EPEC (NCT02373020)
- Testing
- colonoscopic biopsies
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Colorectal Cancer, Colorectal Adenoma
Quantitative Fecal Immunochemical Test for Detection of Colorectal Cancer and Precancerous Lesions in Sohag
Colorectal cancer is a major cause of cancer-related morbidity and mortality worldwide, and early detection significantly improves patient outcomes.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Sessile Serrated Lesion
- Trial name
- NCT07410546
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Colorectal Polyp, Colorectal Neoplasms
Real-time AI-assisted Endocyroscopy for the Diagnosis of Colorectal Lesions
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related death worldwide. Colonoscopy is considered the preferred method of screening for colorectal cancer, and early and…
- Trial name
- NCT06791395
- Testing
- Computer-aided diagnosis (CADx) support tool
- Where
- 3 sites in China
- Volunteers
- 570 people
- Sponsor
- The First Hospital of Jilin University
ColoRectal Cancer, Colonic Polyp
Retrospective Study on Epidemiology of Colorectal Lesions
Retrospective analysis on colonoscopies in the endoscopy unit of the Lyell McEwin Hospital.
- Conditions
- ColoRectal Cancer, Colonic Polyp, Colonic Neoplasms
- Trial name
- NCT03035136
- Volunteers
- 2,658 people, healthy volunteers welcome
- Sponsor
- Lyell McEwin Hospital
Colitis,Ulcerative, Adenomatous Polyposis Coli
Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients
The purpose of this registry is to collect information about patients in which a pouch has been created to improve in the future the quality of the surgery of the pouch.
- Conditions
- Colitis,Ulcerative, Adenomatous Polyposis Coli, Reservoir, Ileoanal
- Trial name
- KOPOF (NCT01604564)
- Where
- Belgium
- Volunteers
- 207 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colonic Neoplasms, Colorectal Neoplasms
Performance and Evaluation for CT Colonography Screening
Colorectal cancer (CRC) is an important United Kingdom healthcare issue affecting 1 in 20 individuals, half of whom will die from the disease.
- Trial name
- PERFECTS (NCT02892721)
- Testing
- Training with feedback
- Where
- United Kingdom
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Rare Diseases, Amyloidosis
Institutional Registry of Rare Diseases
The goal of this observational study is to create a single macro registry system with data collection on common clinical features, grouping the different rare diseases (RD).
- Conditions
- Rare Diseases, Amyloidosis, Sarcoidosis, Phacomatosis
- Trial name
- NCT06573723
- Where
- Argentina
- Volunteers
- 380 people
- Sponsor
- Hospital Italiano de Buenos Aires
Colorectal Cancer, Surgery
Physical Activity in Relation to Surgical Procedures
This study will compare the outcome after surgery between a group of patients that receives instructions for prehabilitation training and one group that received standard treatment.
- Trial name
- NCT02299596
- Testing
- Physical activity
- Where
- 2 sites in Sweden
- Volunteers
- 761 people
- Sponsor
- Sahlgrenska University Hospital
Colorectal Neoplasms
Incidence and Risk Factors of Early Onset Colorectal Cancer
Early onset colorectal cancer (cancer in person younger than 50 years) has increasing incidence last years. The aim of our study was to assess the real-life incidence of early onset colorectal cancer, advanced neoplasias…
- Trial name
- NCT05184751
- Testing
- colonoscopy
- Volunteers
- 18,257 people
- Sponsor
- Hospital Frydek-Mistek
Colorectal Cancer, Lung Cancer
Enhanced Monitoring for Better Recovery and Cancer Experience in Greater Manchester
The EMBRaCE-GM study is a multi-cohort trial designed to efficiently evaluate the range of wearable vital signs monitors that could be used to support patients during cancer treatment.
- Conditions
- Colorectal Cancer, Lung Cancer, Hematological Cancer, CAR T-Cell Therapy
- Trial name
- EMBRaCE-GM (NCT05099237)
- Testing
- OURA Ring, WithingsScan Watch, Isansys Patient Status Engine
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Manchester University NHS Foundation Trust
Breast Cancer, Ovarian Cancer
Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation
Despite relevant clinical and/or familial presentations suggesting a hereditary predisposition (early-onset, multiple primary tumors, familial aggregation), targeted genomic analysis based on the phenotype are often non…
- Conditions
- Breast Cancer, Ovarian Cancer, Colorectal Cancer, Pediatric Cancers
- Trial name
- PANEL (NCT02664389)
- Testing
- Genetic analysis
- Where
- France
- Volunteers
- 289 people
- Sponsor
- University Hospital, Rouen
Breast Cancer, Colorectal Cancer
Cancer Surveillance and Support
This project aims to enhance the support for patients with breast and bowel cancer after treatment. Current follow-up care includes either self-management with patient-initiated contacts (breast cancer) or scheduled hospital…
- Trial name
- CANVAS (NCT04749862)
- Testing
- Online symptom reporting
- Where
- United Kingdom
- Volunteers
- 565 people
- Sponsor
- University of Leeds
Colorectal Cancer (CRC), Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw
CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad
Collect some tumor tissue specimens from patients who have undergone colorectal cancer surgery and conduct experiments such as immunohistochemistry to observe the expression of related genes in colorectal cancer.
- Trial name
- NCT07197151
- Testing
- Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens
- Where
- China
- Volunteers
- 32 people
- Sponsor
- hui hou
Acute Kidney Injury, Cancer Colorectal
Propofol and Sevoflurane Anesthesia in Colorectal Cancer Surgery: Incidence of Acute Kidney Injury
The goal of this observational study is to compare anesthetic modalities (intravenous propofol anesthesia with sevoflurane gas anesthesia) in patients who underwent colorectal cancer resection surgery regarding the outcome of…
- Trial name
- PROSACC (NCT05585866)
- Testing
- Anesthesia Agent
- Where
- Sweden
- Volunteers
- 4,000 people
- Sponsor
- Uppsala University
Melanoma, Solid Tumor
Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors
This is a subprotocol of Master Protocol DAY101-102 and is a Phase 1b/2, multi-center, open label subprotocol of participants ≥12 years of age, with recurrent or progressive solid tumors with alterations in the key proteins of…
- Conditions
- Melanoma, Solid Tumor, Pilocytic Astrocytoma, Non Small Cell Lung Cancer
- Trial name
- NCT07121829
- Testing
- Tovorafenib, Tovorafenib Drug: Pimasertib
- Where
- 10 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- Day One Biopharmaceuticals, Inc.
Carcinomas, Amyloidosis
B-Receptor Signaling in Cardiomyopathy
We hope to determine the importance of different genes (including B receptors) in anthracycline-induced cardiomyopathy. This has important benefits to patients exposed to anthracyclines, as this could help determine whether…
- Conditions
- Carcinomas, Amyloidosis, Anal Cancer, Anemia
- Trial name
- NCT01135849
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Daniel Bernstein
Adenoma, Colorectal Cancer
Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®
The study is intended to compare the detection rate obtained by performing G-EYE® high definition colonoscopy vs. the detection rate obtained by performing ECV high definition colonoscopy.
- Trial name
- NCT04708951
- Testing
- ENDOCUFF VISION® device, G-EYE® colonoscope
- Where
- 3 sites in United States, Germany
- Volunteers
- 970 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colon Cancer
Laparoscopic Colorectal Surgery For Cancer- Long Term Survival
The purpose of this study is to determine the survival after laparoscopic colectomies due to carcinoma.
- Trial name
- NCT00555295
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Anxiety Disorder, Breast Cancer
S1008: Exercise, Diet, & Counseling in Improving Weight Loss in Overweight Female Breast or Colorectal Cancer Survivors
RATIONALE: Physical activity, diet, and counseling may help breast and colorectal cancer survivors to lose weight and improve their quality of life.
- Conditions
- Anxiety Disorder, Breast Cancer, Cognitive/Functional Effects, Colorectal Cancer
- Trial name
- NCT01453452
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- 58 sites in United States
- Volunteers
- 50 people
- Sponsor
- SWOG Cancer Research Network