Clinical trials: Colonic Cancer
Cancer Colon, Colectomy
Is the Distance of Patients From Rouen University Hospital Influencing the Time Between Colectomy and First Chemotherapy Cure for Colon Cancer?
This project has for objective to demonstrate that the increase of the distance "Patient home - center of treatment" may be associated with significant, other noticeable, noted events.
- Conditions
- Cancer Colon, Colectomy, Chemotherapy
- Trial name
- DICHIMIO (NCT03722121)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Rouen
Familial Adenomatous Polyposis (FAP), Attenuated Familial Adenomatous Polyposis (AFAP)
Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare)
RIPAF (Rete Italiana Poliposi Adenomatosa Familiare) is a national, multicenter observational registry designed to establish a coordinated Italian network for the management of Familial Adenomatous Polyposis (FAP) and related…
- Conditions
- Familial Adenomatous Polyposis (FAP), Attenuated Familial Adenomatous Polyposis (AFAP), MUTYH-Associated Polyposis (MAP), Non-APC/MUTYH Associated Polyposis (NAMP)
- Trial name
- RIPAF (NCT07461246)
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Colorectal Cancer, Precancerous Condition
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of celecoxib may keep polyps and colorectal cancer from forming in patients with familial adenomatous polyposis.
- Trial name
- NCT00685568
- Testing
- celecoxib
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- M.D. Anderson Cancer Center
Colon Cancer
Definition of Surgical Technique of Lymphadenectomy and Complete Mesocolon Excision for Radical Right Colectomy: a Delphi Consensus
A Delphi consensus to define surgical steps of lymphadenectomy and complete mesocolic excision for radical right colectomy
- Trial name
- NCT05544474
- Testing
- Delphi questionnaire
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Cancer of Colon
Tumor Deposits in Cancer Colon
1. Assessment of correlation between tumor deposits and clinicopathological characteristics of colorectal cancer. 2. Detection of association between tumor deposits and stage of colorectal cancer. 3.
- Trial name
- NCT04773626
- Volunteers
- 100 people
- Sponsor
- Assiut University
Colorectal Cancer
Genetic Study of Patients and Families With a History of Colorectal Cancer
RATIONALE: Determination of genetic markers for colorectal cancer may help doctors to identify patients who are at risk. PURPOSE: Genetic testing study of patients and families with a history of colorectal cancer to identify…
- Trial name
- NCT00003648
- Testing
- DNA stability analysis, gene rearrangement analysis
- Where
- 12 sites in United States, Canada
- Volunteers
- 1,500 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colorectal Carcinoma, Cancer
Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies
This original research investigates the critical issue of gastrointestinal (GI) second primary malignancies (SPMs) in patients with signet ring cell carcinoma (SRCC), a rare and aggressive subtype of colorectal cancer.
- Conditions
- Colorectal Carcinoma, Cancer, Signet Ring Adenocarcinoma of the Colon
- Trial name
- NCT06978595
- Where
- Egypt
- Volunteers
- 8,171 people
- Sponsor
- asmaa salama ibrahim
Enteropathogenic Escherichia Coli ., Colorectal Carcinoma
Enteropathogenic Escherichia Coli (EPEC): Does it Have a Role in Colorectal Tumourigenesis?
Despite the characterization of many aetiologic genetic changes. The specific causative factors in the development of sporadic colorectal cancer remain unclear.
- Trial name
- EPEC (NCT02373020)
- Testing
- colonoscopic biopsies
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Spinal Muscular Atrophy, Neonatal Hyperbilirubinemia
Establishing Novel Detection Techniques for Various Genetic-Related Diseases by Applying DHPLC Platform.
In this, here we want to present a new method for analysis variation in gene copy number for patients and carriers of SMA. This is a relative quantitation method and, therefore, relies on the inclusion of one or more internal…
- Conditions
- Spinal Muscular Atrophy, Neonatal Hyperbilirubinemia, Colon Cancer
- Trial name
- NCT00154960
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Health Behavior, Colorectal Neoplasms
Health Behavior Change in High-Risk Colorectal Cancer Individuals
Background Colorectal cancer is a significant health concern. For individuals identified as being at high risk for developing this disease, adopting healthy lifestyle behaviors is a powerful way to lower that risk.
- Conditions
- Health Behavior, Colorectal Neoplasms, Primary Prevention/Methods
- Trial name
- NCT07262840
- Testing
- Multi-component Health Promotion Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University, China
Colorectal Adenoma, Colorectal Polyp
EndoRings Colonoscopy vs Standard Colonoscopy
The study aims to compare the results between a standard colonoscopy to a colonoscopy with an attachment on the distal end of the colonoscope.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colon Cancer
- Trial name
- NCT03418662
- Testing
- EndoRings device
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Indiana University
Metastatic Colorectal Cancer
Evaluation of VEGF Polymorphism as Predictive Factor in Metastatic Colorectal Cancer Treated With Folfiri Plus Bevacizumab
-1498C/T VEGF polymorphism, as suggested by a recent retrospective analysis, seems to have a role in predicting the efficacy of Bevacizumab plus FOLFIRI in first-line treatment of metastatic colorectal cancer patients.
- Trial name
- PROVETTA (NCT01363739)
- Where
- Italy
- Volunteers
- 265 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Colon Cancer, Diverticulitis
General Surgical Outcomes Quality Improvement Database (UH-SOCRATES)
A database has been established to track the outcomes of all cases performed in the University Hospitals Department of Surgery in an effort to improve quality of surgical performance and case management.
- Conditions
- Colon Cancer, Diverticulitis, Colorectal Polyps, Crohn's Disease
- Trial name
- SOCRATES (NCT00622557)
- Where
- United States
- Volunteers
- 200,000 people
- Sponsor
- University Hospitals Cleveland Medical Center
Surgical Site Infection, Colorectal Cancer
Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs: A Propensity Analysis
Surgical site infections (SSIs) are a major postoperative complication after colorectal surgery. Current study aims to evaluate prophylactic function of oral antibiotic intake (OA) in combination with mechanical bowel preparation…
- Trial name
- NCT04258098
- Testing
- Oral antibiotics ( Streptomycin ,metronidazole )
- Volunteers
- 806 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Recurrent Colon Cancer, Recurrent Rectal Cancer
Imatinib Mesylate in Treating Patients With Stage IV Colorectal Cancer
Phase II trial to study the effectiveness of imatinib mesylate in treating patients who have stage IV colorectal cancer. Imatinib mesylate may interfere with the growth of tumor cells by blocking certain enzymes necessary for…
- Conditions
- Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV Colon Cancer, Stage IV Rectal Cancer
- Trial name
- NCT00041340
- Testing
- imatinib mesylate, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer (CRC) and Pancreatic Cancer (PaCa)
Allocating Resources for Cancer Care in Times of the Sars-CoV-2 Outbreak. Health Care Research
The focus on treatment of COVID19 patients during the Sars-CoV-2 outbreak has most likely implications for the extent and quality of diagnosis and treatment of non-COVID19 patients.
- Trial name
- NCT05479292
- Testing
- Sars-CoV-2 outbreak
- Where
- Germany
- Volunteers
- 6,500 people
- Sponsor
- Technische Universität Dresden
Inflammatory Bowel Diseases, Crohn Disease
De-escalation of Anti-TNF Therapy in Inflammatory Bowel Disease
BACKGROUND/RATIONALE: Treatment outcomes of patients with inflammatory bowel disease (IBD) have improved enormously during the past decade due to the use of anti-tumour necrosis factor (anti-TNF) therapy.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Colitis, Ulcerative
- Trial name
- FREE (NCT04646187)
- Testing
- Infliximab, Adalimumab
- Where
- 7 sites in Belgium, Netherlands and 1 more
- Volunteers
- 148 people
- Sponsor
- University Medical Center Groningen
Colorectal Cancer
The Impact of Covid-19 Pandemic on Colorectal Cancer Prevention Due to Delays in Diagnosis: a Global Study
Screening programs have been associated with a substantial reduction in colorectal cancer (CRC) mortality through endoscopic resection of preneoplastic lesions and detection of early-stage invasive cancers.
- Trial name
- COVID_CRC (NCT04637893)
- Testing
- Colonoscopy
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Clinico Humanitas
Malignant Solid Tumors, Primary Brain Tumor
Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research
The investigators will collect biosamples of patient blood and tumour tissue for further immunological analysis of blood cell subpopulations, immunosupressive factors concentration, HLA expression an lymphocytes and tumour…
- Conditions
- Malignant Solid Tumors, Primary Brain Tumor, Melanoma, Soft Tissue Sarcoma
- Trial name
- REGATA (NCT05539677)
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Breast Neoplasms, Colonic Neoplasms
A Phase II Clinical Trial of Suppression of Human Antimouse Antibody and Human Antitoxin Response to Immunotoxin LMB-1 by Rituximab
This is a phase II clinical and pharmacokinetic study of suppression of human antimouse (HAMA) and antitoxin antibodies (HATA) to immunotoxin LMB-1 by Rituximab (anti-CD20).
- Conditions
- Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Pancreatic Neoplasms
- Trial name
- NCT00001805
- Testing
- Rituximab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)