Clinical trials: Colorectal
Cancer Colon, Colectomy
Is the Distance of Patients From Rouen University Hospital Influencing the Time Between Colectomy and First Chemotherapy Cure for Colon Cancer?
This project has for objective to demonstrate that the increase of the distance "Patient home - center of treatment" may be associated with significant, other noticeable, noted events.
- Conditions
- Cancer Colon, Colectomy, Chemotherapy
- Trial name
- DICHIMIO (NCT03722121)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Rouen
Colorectal Cancer
Towards Painless Colonoscopy
One of the major barriers to CRC screening participation is a negative perception of colonoscopy as a painful and unpleasant procedure.
- Trial name
- NCT04093687
- Testing
- Endoscopist's training
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Rectal Cancer
Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the Rectum
The study enrols patients with operative rectal cancer qualified for laparoscopic anterior resection. Patients are given first dose of indocyanine green iv intraoperatively (ICG) before choosing the appropriate site of the…
- Trial name
- NCT05263336
- Testing
- Verdye Green
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Jagiellonian University
Optimization of Treatment
Comparison of Simultaneous Laparoscopic and Open Operations for Synchronous Liver Metastases With Colorectal Cancer
retrospective analysis of medical records of patients with synchronous liver metastatic colorectal cancer, who underwent simultaneous operations on the intestine and on the liver, from January 2011 to November 2020 at the Russian…
- Trial name
- NCT04907435
- Testing
- simultaneous operations
- Volunteers
- 42 people
- Sponsor
- Federal State Budgetary Institution Russian Scientific Center of Roentgenoradiology of the Ministry
Ulcerative Colitis, Familial Adenomatous Polyposis
Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch?
Total proctocolectomy with ileal pouch anal anastomosis is the first choice surgical operation for management of ulcerative colitis and familial adenomatous polyposis.
- Trial name
- NCT01173250
- Testing
- adding diverting ileostomy, omitting diverting ileostomy
- Sponsor
- Mansoura University
Metastatic Colorectal Cancer
A Post-Marketing Surveillance Study On Erbitux® (Cetuximab) In Patients With Metastatic Colorectal Cancer Refractory To Irinotecan Containing Treatment
A post marketing surveillance, prospective study to collect safety information from 250 subjects with epidermal growth factor receptor (EGFR) expressing, KRAS wild-type metastatic colorectal cancer treated with Erbitux as final…
- Trial name
- NCT01134640
- Where
- 15 sites in Taiwan
- Volunteers
- 286 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Endocytoscopy
Clinical Study on the Diagnosis of Colorectal Lesions by Real-time Artificial Intelligence Assisted Endocytoscopy Combined With Narrow Band Imaging
Colorectal cancer (colorectal cancer, CRC) is the third most common malignant tumor globally and the second leading cause of cancer-related deaths.
- Trial name
- NCT06982885
- Testing
- artificial intelligence
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The First Hospital of Jilin University
Colorectal Neoplasms, Lung Neoplasms
Figitumumab Combined With Pegvisomant For Advanced Solid Tumors
This is a Phase 1 study investigating the safety and tolerability of Figitumumab plus Pegvisomant for treatment of advanced solid tumors.
- Conditions
- Colorectal Neoplasms, Lung Neoplasms, Breast Neoplasms, Prostatic Neoplasms
- Trial name
- NCT00976508
- Testing
- figitumumab, pegvisomant
- Where
- 5 sites in United States, Canada and 2 more
- Volunteers
- 24 people
- Sponsor
- Pfizer
Colorectal Cancer
Tissue and Serum Collection From Colorectal Cancer Patients
To establish a serum and tissue bank with specimens form patients with colorectal cancer, for subsequent immunological and biochemical analysis.
- Trial name
- NCT00579891
- Where
- United States
- Volunteers
- 726 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer
Bryostatin 1 in Treating Patients With Metastatic Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of bryostatin 1 in treating patients with metastatic…
- Trial name
- NCT00003220
- Testing
- bryostatin 1
- Where
- 2 sites in United States
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Colorectal Adenoma, Colorectal Cancer Control and Prevention
6-year Follow-up Data After the Berberine Intervention Trial
Colorectal cancer (CRC) is a common malignancy of the digestive tract, which constitutes a major public health burden. Almost 90% of CRC cases progress from precursor adenomatous polyps through adenoma-carcinoma sequence.
- Conditions
- Colorectal Adenoma, Colorectal Cancer Control and Prevention, Colorectal Polyps
- Trial name
- NCT06629051
- Testing
- Berberine Hydrochloride
- Where
- China
- Volunteers
- 891 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Colorectal Cancer, Neoplasm of Uncertain Malignant Potential
Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer
RATIONALE: Diagnostic imaging procedures, such as fludeoxyglucose F 18 PET, may be effective in detecting cancer or recurrence of cancer, or premalignant polyps.
- Trial name
- NCT00550628
- Testing
- DNA methylation analysis, fluorescence in situ hybridization, gene expression analysis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ewing Sarcoma, PEComa
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
This study investigates the safety/toxicity and potential anti-tumor activity of sequential administration of nivolumab and escalating doses of the mammalian target of rapamycin (mTOR) inhibitor nab-rapamycin (ABI-009) in…
- Conditions
- Ewing Sarcoma, PEComa, Epithelioid Sarcoma, Desmoid Tumor
- Trial name
- NCT03190174
- Testing
- Nab-Rapamycin, Nivolumab
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Sarcoma Oncology Research Center, LLC
Colon Cancer, Precancerous Condition
Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer
This randomized phase II trial is studying how well aspirin works in preventing colorectal cancer in patients at increased risk of colorectal cancer. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Conditions
- Colon Cancer, Precancerous Condition, Rectal Cancer
- Trial name
- NCT00468910
- Testing
- acetylsalicylic acid, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- National Cancer Institute (NCI)
Return of Bowel Function After Colon Surgery
The Influence of Ambulation on the Return of Bowel Function After Colorectal Surgery
"Fast-track" or "enhanced recovery" programs, which are the new standardized accelerated clinical pathways for post-operative care for colorectal surgeries, have three goals: to 1) quicken the return of bowel function (as…
- Trial name
- NCT01241123
- Testing
- Ambulation regimen, Sitz-Markers, Daily abdominal x-rays
- Where
- United States
- Sponsor
- United States Naval Medical Center, Portsmouth
Liver Neoplasms, Liver/Hepatobiliary Cancer
CE-IOUS Impact on Surgical Strategy of Liver Tumours and Liver Metastases
Contrast-enhanced intraoperative ultrasound (CE-IOUS) plays an increasingly important role in the surgical therapy planning of primary liver lesions as well as liver metastases.
- Conditions
- Liver Neoplasms, Liver/Hepatobiliary Cancer, Colorectal Cancer Metastatic, Metastases
- Trial name
- NCT05261113
- Testing
- CE-IOUS
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Regensburg
Colorectal Cancer
The Effect of Routine Video-recording on Colonoscopy Quality Indicators.
Routine video recording of the colonoscopy examination has been proposed as a simple and easy to implement method that could improve the quality of colonoscopy.
- Trial name
- NCT02054923
- Testing
- Implementation of routine videorecording, No routine videorecording
- Where
- Poland
- Volunteers
- 5,200 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Rectal Cancer, LARS - Low Anterior Resection Syndrome
Comparison of Six Different Machine Learning Methods With Traditional Model for Low Anterior Resection Syndrome After Minimally Invasive Surgery for Rectal Cancer -- Development and External Validation of a Nomogram : A Dual-center Cohort Study
Following thorough screening based on inclusion and exclusion criteria, patients from the two sizable medical centers were split up into two cohorts for this study.
- Trial name
- NCT07267767
- Testing
- nCRT, BMI, Distance from AV
- Volunteers
- 3,500 people
- Sponsor
- Northern Jiangsu People's Hospital
Breast Carcinoma, Cervical Carcinoma
The Ohio State University (OSU) SCREEN Community Program
This clinical trial develops and tests how well a multi-level intervention (MLI), The Ohio State University (OSU) SCREEN Community Program, works to increase screening and follow-up for breast, cervical and colorectal (CRC)…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma
- Trial name
- NCT06666192
- Testing
- Cancer Screening, Discussion, Educational Activity
- Where
- United States
- Volunteers
- 2,067 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Rectal Cancer, MRI
Predicting Locally Advanced Rectal Cancer Response to NCT and NCRT With MRI
This trial was designed to to study whether there is a difference in MRI image evaluation between NCRT and NCT, and try to build a model to predict the efficacy of neoadjuvant therapy by combining multiple imaging indexes.
- Trial name
- NCT04392609
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ziqiang Wang,MD