Clinical trials: Coma, Traumatic
Consciousness Disorders, Persistent Vegetative State
Multimodal Assessment and Prognosis in Disorders of Consciousness After Severe Brain Injury (CyDoC-MAP)
After a severe brain injury some patients survive but cannot communicate, and deciding early which of them are likely to recover consciousness remains one of the hardest problems in neurocritical care.
- Conditions
- Consciousness Disorders, Persistent Vegetative State, Unresponsive Wakefulness Syndrome, Minimally Conscious State
- Trial name
- CyDoC-MAP (NCT07736820)
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Nicosia General Hospital
Impaired Consciousness
FOUR Score in Children With Non-traumatic Impairment of Consciousness
Hypothesis: FOUR score is a better predictor of outcome (in hospital mortality and functional outcome at discharge) than GCS in children 5- 18 years age admitted in pediatric ward/ ICU with non-traumatic impaired consciousness.
- Trial name
- NCT01537913
- Volunteers
- 70 people
- Sponsor
- All India Institute of Medical Sciences
Trauma
The Predictive Performance of Glasgow Coma Scale in Relation to Time
The study aims to assess whether time between injury and first Glasgow Coma Scale measurement will affect its predictive value.
- Trial name
- NCT03450525
- Testing
- No intervention
- Where
- 4 sites in India
- Volunteers
- 16,000 people
- Sponsor
- Karolinska Institutet
Traumatic Brain Injury
Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension
Objective: to assess the effectiveness of pentobarbital and thiopental to control raised intracranial pressure (ICP), refractory to first level measures, in patients with severe traumatic brain injury.
- Trial name
- NCT00622570
- Testing
- Pentobarbital, thiopental
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Hospital Universitari Son Dureta
Brain Death
Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal Injury
This is the proof of concept study with multi-modality approach (using intra-thecal bioactive peptides, stem cells, laser and transcranial IV laser and Median Nerve stimulation as adjuvants) in cases of brain death due to…
- Trial name
- NCT02742857
- Testing
- BQ-A Peptide Extract, Mesenchymal Stem Cells, Transcranial Laser Therapy
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bioquark Inc.
Impaired Consciousness
Outcome Predictors of Non Traumatic Coma in Children
To catch the high risk comatosed child to improve service and direct the limited resources to those children in countries with limited resources .
- Trial name
- NCT03618745
- Testing
- CT brain
- Volunteers
- 50 people
- Sponsor
- Assiut University
Brain Injuries, Acute, Brain Injuries, Traumatic
Antiseizure Medication in Seizure Networks at Early Acute Brain Injury
The goal of this clinical trial is to explore the effect of FDA-approved antiseizure drugs in the brain connectivity patterns of severe and moderate acute brain injury patients with suppression of consciousness.
- Conditions
- Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia
- Trial name
- NCT06081283
- Testing
- Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill