Clinical trials: Communication Disabilities
Heathly Subjects Susceptible to SARS-CoV-2 Infection
Microbiome-Based Risk Prediction of SARS-CoV-2 in Children and Families (PREDICOL)
The goal of this observational cohort study is to evaluate the association between gut microbiota composition, dietary patterns, lifestyle-related factors, and neurodevelopmental outcomes, as well as susceptibility to SARS-CoV-2…
- Trial name
- PREDICOL (NCT07717008)
- Where
- Spain
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
Neurodevelopmental Disorders, Intellectual Disability
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND (developmental delay, epilepsy and neonatal diabetes) due to the V59M…
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD
- Trial name
- iDEND (NCT05751525)
- Testing
- Sulfonylurea
- Where
- 4 sites in United States, Italy and 2 more
- Volunteers
- 21 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Children, Only, Vestibular Disorder
Vestibular and Postural Function in Children Suspected of Balance Disorders
The goal of this prospective cohort study is to investigate the vestibular function in children suspected of balance disorders, and to follow up on their balance progressions after rehabilitation.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function Disorder, Development Delay
- Trial name
- VASIC (NCT06229704)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Gødstrup Hospital
Autism Spectrum Disorder, Developmental Delay
Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism
In this study, the investigators are trying to find new ways to screen for autism spectrum disorder (ASD) in young children. The investigators want to see if people like pediatricians can screen children for ASD while a…
- Trial name
- NCT03847337
- Testing
- Telehealth-Screening Tool for Autism in Toddlers (STAT), Telehealth-Autism Spectrum Disorder-Pediatrics (ASD-PEDS)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Vanderbilt University Medical Center
Dyslexia, Specific Learning Disability
Efficacy of rTMS as an Adjunct to AI Enabled Remedial Intervention in Children With Dyslexia
Dyslexia is the most common neurobehavioral disorder affecting children, with prevalence rates ranging from 17.5% to 21%. Studies have shown incomplete response to remediation and behavioural therapies in children with dyslexia.
- Conditions
- Dyslexia, Specific Learning Disability, Transcranial Magnetic Stimulation
- Trial name
- NCT05923645
- Testing
- Transcranial magnetic stimulation (Hf rTMS)
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Down Syndrome, Speech and Language Disorder
Building Sentences With Preschoolers Who Use AAC
The focus of this investigation is to compare the effectiveness of the AAC Generative Language Intervention approach to an AAC Standard of Care condition on preschool sentence productions.
- Conditions
- Down Syndrome, Speech and Language Disorder, Speech Disorders in Children, Speech Intelligibility
- Trial name
- NCT03538925
- Testing
- AAC Generative Language Intervention, Standard of Care / Business as Usual
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Language Disorders in Children
Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties
In the proposed project, the investigators will conduct a multisite randomized controlled trial (RCT) to determine the efficacy of Let's Know!2, a small-group, language focused comprehension intervention, on children's lower- and…
- Trial name
- LK!2 (NCT05133479)
- Testing
- Let's Know! small-group or TierL 2 Intervention
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Cerebral Palsy, Spinal Muscular Atrophy
Pediatric Powered Wheelchair Standing Devices: An Exploratory Study
For children who use a power wheelchair, a powered wheelchair standing device (PWSD) may be considered for daily use. A PWSD allows a child to electronically move between sitting and standing and can be driven in either position.
- Conditions
- Cerebral Palsy, Spinal Muscular Atrophy, Spinal Cord Injuries, Spina Bifida
- Trial name
- NCT05117827
- Testing
- Power Wheelchair Standing Device
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Sickle Cell Disease
Testing the Sickle Cell Caregiver Collaboration for Child Development (SCCCD) Intervention
Sickle cell disease affects 100,000 people and 2,000 newborns each year; 50% of these children have a developmental deficit (>2 SD) before the age of 3.
- Trial name
- SCCCD (NCT06562439)
- Testing
- Sickle Cell Collaboration for Child Development
- Where
- United States
- Sponsor
- Washington University School of Medicine
Developmental Delay, Skeletal Abnormalities
Biomarker for Sly Disease (MPS VII) (BioSly)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Sly disease from blood (plasma)
- Conditions
- Developmental Delay, Skeletal Abnormalities, Hepatomegaly, Splenomegaly
- Trial name
- BioSly (NCT02298699)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06001866
- Testing
- Retrieval-based verb learning: Repeated Spaced Retrieval condition, Retrieval-based verb learning: Repeated Study condition
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dyslexia, Speech Therapy
Comparative Impact of Protocolized Management, Intensive Rehabilitation Versus Long-term Classic Rehabilitation of Dyslexic Children.
Dyslexia is characterized by difficulties with accurate and/or fluent word recognition and by poor spelling and decoding abilities. In France, dyslexia is a public health disorder.
- Conditions
- Dyslexia, Speech Therapy, Children, Only
- Trial name
- INTENS-DYS (NCT05383937)
- Testing
- Speech Therapy INTENS-DYS
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Developmental Language Disorder, Language Disorders in Children
The Influence of Immersive Virtual Field Trips on Academic Vocabulary
The purpose of this study is to investigate an immersive virtual field trip (iVFT) on topic specific academic vocabulary for students with developmental language disorder (DLD).
- Trial name
- NCT05242575
- Testing
- The information provided in the iVFT and control book parallel one another.
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Salus University
Dyscalculia
Automatization of Counting Procedures in Children With Dyscalculia
Researchers in numerical cognition usually think that the greatest and most common difficulty in children suffering from dyscalculia is retrieval of arithmetic facts from long-term memory.
- Trial name
- PROCEDYS (NCT03354481)
- Testing
- Arithmetic facts solving
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Hospices Civils de Lyon
ADHD - Attention Deficit Disorder With Hyperactivity, Specific Learning Disorder
White Noise in SLD and ADHD
White noise has been shown to improve working memory and attention in children diagnosed with ADHD . These cognitive abilities are fundamental to the acquisition of reading and writing skills.
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Specific Learning Disorder, Specific Learning Disability
- Trial name
- WHITE NOISE (NCT07376902)
- Testing
- White noise, No white noise
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele Roma
Neurological Impairments, Genetic Syndrome
Speech Therapy and Parenting for Early Socio-communicAtive sKills
Every year, millions of children are diagnosed with neurodevelopmental disabilities. This term covers a wide range of conditions, from genetic syndromes to brain injuries such as cerebral palsy.
- Conditions
- Neurological Impairments, Genetic Syndrome, Neurodevelopmental Disability, Developmental Delays
- Trial name
- SPEAK (NCT06666777)
- Testing
- Intervention focused on intersubjective prelinguistic and socio-communicative skills, Standard speech therapy intervention
- Where
- 9 sites in Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Neurodevelopmental Disorders, Autism Spectrum Disorder
A Game-based Neurodevelopmental Assessment for Young Children
The aim of this study is to evaluate a novel tablet game-based neurodevelopmental assessment tool for young children aged 3 to 8 years old.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Dyslexia
- Trial name
- BRIGHTEN (NCT05780853)
- Testing
- Tablet Game-based Assessment - YARN assessment service, Adaptive Behavior Assessment System, Third Edition (ABAS-3), Demographic questionnaire
- Where
- United Kingdom
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Brightlobe Limited
Dyslexia
taVNS for Letter Learning in Dyslexia
This is a pilot study to establish feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) for improving letter-learning in adolescents with dyslexia.
- Trial name
- NCT06127550
- Testing
- active taVNS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Florida
Learning Disabilities
Exercise and Physical Fitness in Children With Specific Learning Disabilities
Specific learning disabilities (SLD) are characterized by difficulties in reading, comprehension, arithmetic, and written expression, often accompanied by impairments in motor skills, balance, and coordination.
- Trial name
- NCT07230093
- Testing
- Combined Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Academic Skill Disorder, Child Behavior
Impact of Neuro-linguistic Programming on Schoolchildren's Performance
Neuro-Linguistic Programming (NLP) is a methodology developed in the 1970s by Richard Bandler and John Grinder, based on the idea that language and behavior are interconnected and can be systematically modeled and changed.
- Trial name
- NCT05870085
- Testing
- Neuro-linguistic program
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Lebanese University