Clinical trials: Community Acquired Pneumonia, Severe
Pneumonia, Bacterial, Community-Acquired Infections
A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia
The purpose of this study is to evaluate the safety and tolerability of doripenem compared to cefepime in children hospitalized with pneumonia.
- Conditions
- Pneumonia, Bacterial, Community-Acquired Infections, Nosocomial Infection, Pneumonia, Ventilator-Associated
- Trial name
- NCT01110421
- Testing
- Cefepime, Doripenem, Amoxicillin/clavulanate potassium
- Where
- 25 sites in United States, Argentina and 8 more
- Volunteers
- 7 people
- Sponsor
- Janssen Research & Development, LLC
Respiratory Tract Diseases, Influenza (Pandemic)
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of hospitalised…
- Conditions
- Respiratory Tract Diseases, Influenza (Pandemic), Influenza, Community Acquired Pneumonia
- Trial name
- REMAP-CAP (NCT02735707)
- Testing
- Ceftriaxone + Macrolide, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam + Macrolide
- Where
- 408 sites in United States, Australia and 27 more
- Volunteers
- 20,000 people
- Sponsor
- UMC Utrecht
Community-acquired Pneumonia
Clinical Efficacy of Amoxicillin Given Twice or Three Times a Day Among Children With Non-severe Pneumonia
The purpose of the study is to compare the clinical efficacy of amoxicillin given twice or three times a day to children with non-severe community-acquired pneumonia.
- Trial name
- PNEUMOPACEf (NCT01200706)
- Testing
- Amoxicillin
- Where
- Brazil
- Volunteers
- 820 people
- Sponsor
- Federal University of Bahia
Severe Pneumonia
Research on the Treatment of Severe Community-acquired Pneumonia in Children
The need for glucocorticoid therapy in children with severe community-acquired pneumonia in the acute phase of the disease remains unclear.
- Trial name
- NCT05768204
- Testing
- Prednisolone Acetate
- Where
- 3 sites in China
- Volunteers
- 160 people
- Sponsor
- Baoping XU
Pneumonia, Child
Predicting Severe Outcomes Among Children Hospitalized With Community-acquired Pneumonia
In this study, investigators aimed to develop and validate a risk score to predict severe outcomes (e.g., mortality and ICU admission) in children who were admitted to the Children's Hospital of Fudan University between 2017 and…
- Conditions
- Pneumonia, Child, Prognosis
- Trial name
- NCT05744609
- Testing
- exposures of interest: epidemiological data, clinical characteristics, laboratory data, and chest radiographic reports
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Children's Hospital of Fudan University
Pneumonia
Tifacogin for the Treatment of Patients With Severe Community-Acquired Pneumonia
The purpose of this study is to determine whether tifacogin is effective and safe in the treatment of patients with severe community-acquired pneumonia.
- Trial name
- NCT00084071
- Testing
- Tifacogin
- Where
- 150 sites in United States, Argentina and 16 more
- Volunteers
- 2,136 people
- Sponsor
- Novartis Pharmaceuticals
Community-acquired Pneumonia
Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia.
The aim of this study will be to evaluate whether a twice-daily antibiotic regimen is non-inferior to a thrice-daily regimen for the treatment of non-severe community acquired pneumonia in children presenting at a paediatric…
- Trial name
- NCT03031210
- Testing
- Amoxicillin
- Where
- Canada
- Volunteers
- 1,370 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital