Clinical trials: Community-based
Mental Health Disorder, Social Isolation
Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe
A community-based peer support intervention for adolescent mothers aged 14-18 years in Harare, Zimbabwe was developed and tested in partnership with adolescent mothers, community health workers, and key community stakeholders.
- Conditions
- Mental Health Disorder, Social Isolation, Stigma, Social
- Trial name
- NCT05213182
- Testing
- Young Women of Today
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- West Chester University of Pennsylvania
Health Systems, Electronic Community Health Information Systems
Digital Data Linkage and Scheduling to Track Pregnancy With or Without Community Data Use to Increase Antenatal Clinic Uptake in Western Kenya.
The investigators propose to increase ANC uptake through a health systems strengthening approach that links digital data platforms and trains community Work Improvement Teams (WITs) to use these data to identify problems and come…
- Conditions
- Health Systems, Electronic Community Health Information Systems, Antenatal Clinic Uptake, Pregnancy
- Trial name
- C-it-DU-it (NCT05929586)
- Testing
- The combined "C-it DU-it" intervention: community data use for ANC
- Where
- Kenya
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Death, HIV Infection
Community-based Evaluation of a Pilot PMTCT Project in Kafue District
In this study, the investigators will assess the population effectiveness of using routine HAART as a PMTCT strategy, through a community-based survey.
- Trial name
- NCT00753428
- Testing
- Community-based Survey
- Where
- Zambia
- Volunteers
- 4,129 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV CDC Category A1
A Community-based Implementation Model for HIV Prevention and Testing in Malawi
This implementation study is testing whether community members can use a 3-step model (prepare, roll-out and sustain) to implement an efficacious peer group HIV prevention intervention with fidelity and effectiveness in a single…
- Trial name
- NCT02765659
- Testing
- Mzake ndi Mzake T1, Mzake ndi Mzake T2, Mzake ndi Mzake T3
- Where
- Malawi
- Volunteers
- 1,353 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Pregnancy Related
Chamas for Change Validation
This team has shown that chamas can be tailored to increase the uptake of health services in pregnancy and infancy, sustain themselves beyond the period of funding and become integrated within a county's health strategy.
- Trial name
- NCT03187873
- Testing
- Chama cha MamaToto
- Where
- Kenya
- Volunteers
- 3,040 people, healthy volunteers welcome
- Sponsor
- Moi University
Alcohol Abuse
A Community-Based Strategy for Preventing Underage Drinking
This project evaluates a combination of policy and social influence interventions to reduce adolescent alcohol use and its sequelae.
- Trial name
- NCT02448134
- Testing
- Youth Access
- Where
- United States
- Volunteers
- 7,379 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Malnutrition, Child
Community-based, Controlled, Open-label, Cluster-randomized Trial for the Reduction of Chronic Malnutrition in Children Under Two Years of Age, With Three Intervention Arms Grouped by Clusters, in Two Provinces in Southern Angola, Huíla and Cunene.
The severity of the stunting in the provinces of Huíla and Cunene, Angola, in children aged 6 to 59 months is considered to be very high, as defined by the World Health Organization (WHO) classification of 2018.
- Trial name
- NCT05571280
- Testing
- Nutritional Supplementation, Money transfers, Standard intervention
- Where
- 2 sites in Angola
- Volunteers
- 1,423 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Point-of-Care Testing, HIV
Ayaangwaamiziwin Initiative: Carefulness and Preparedness
The goal of this clinical trial is to implement a test, treat, and connect intervention approach using HIV and syphilis rapid point-of-care (POC) testing in 3 Canadian Prairie provinces (Alberta, Manitoba, and Saskatchewan)…
- Conditions
- Point-of-Care Testing, HIV, Syphilis
- Trial name
- AI (NCT06893159)
- Testing
- INSTI HIV-1/2 Antibody Test, INSTI Multiplex HIV-1/2 Syphilis Antibody Test, Multiplo Complete Syphilis (TP/nTP) Antibody Test
- Where
- 8 sites in Canada
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Jaundice, Neonatal, Neonatal Diseases and Abnormalities
Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in Newborns
Newborn jaundice, or accumulation of bilirubin molecules in blood, affects 60-80% of newborns and, in severe cases, places newborns at risk of brain damage and death.
- Conditions
- Jaundice, Neonatal, Neonatal Diseases and Abnormalities, Neonatal Hyperbilirubinemia, Screening Tool
- Trial name
- NCT06687746
- Testing
- Bili-ruler
- Where
- 5 sites in India, Kenya and 2 more
- Volunteers
- 4,060 people, healthy volunteers welcome
- Sponsor
- George Washington University
Maternal Morbidity and Mortality, Stillbirth and Neonatal Mortality
Emergency Obstetric and Neonatal Care: The EmONC Trial
The objective of this cluster randomized controlled trial is to reduce maternal and neonatal mortality by increasing access to and improving the quality of obstetric and neonatal care for pregnant women in study clusters.
- Trial name
- EmONC (NCT01073488)
- Testing
- Community Mobilization, HBLSS and facility improvement
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 267,181 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Health Behavior
Promoting Family Health, Happiness, and Harmony Through a Community-based "Learning Family" Campaign
According to the Social Welfare Department statistics, Kwun Tong has been ranked as the highest for the reported cases of elderly abuse (12.3%), the second and fourth highest for the reported cases of battered spouse (9.2%) and…
- Trial name
- NCT02851667
- Testing
- Resident training programs
- Where
- Hong Kong
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Tuberculosis, HIV/AIDS
TB Reduction Through ART and TB Screening Project
Tuberculosis (TB) has overtaken HIV as the leading infectious cause of death worldwide and requires a major policy shift for it to be controlled in line with the WHO Stop-TB goal to "end TB".
- Trial name
- TREATS (NCT03739736)
- Testing
- Combination of TB/HIV prevention activities (arm A), Combination of TB/HIV prevention activities (arm B), Standard of care (arm C)
- Where
- 2 sites in South Africa, Zambia
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Pediatric, Well Child Care
Comparing a Team-Based Approach to Standard Well-Child Visits To Improve Preventive Care Services
Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT) is a team-based approach to care that utilizes a community health worker in a health educator role ("Parent's Coach") to provide many of the Well-Child Care…
- Trial name
- NCT05852392
- Testing
- Adapted PARENT Model
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity & Overweight
Efficacy of Center-based Childcare to Mitigate Unhealthy Weight Gain in Preschoolers From Low-income Households During the Summer
Studies show that preschool-age children are especially vulnerable to accelerated weight gain during the summer, with those from low-income households (≤185% poverty level or Medicaid eligible - the target population for this…
- Trial name
- NCT07583459
- Testing
- Childcare
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Onchocerciasis, Epilepsy
Impact of a Bi-annual CDTI on the Incidence of Epilepsy in an Onchocerciasis-endemic Area
Onchocerciasis is a neglected tropical disease associated with epilepsy, particularly in areas of high Onchocerciasis volvulus transmission.
- Trial name
- OAETanzania (NCT05749653)
- Testing
- Bi-annual CDTI
- Where
- Tanzania
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
MISC Intervention, Treatment as Usual
MISC-IPV: A Community-Based Intervention for Children Traumatized by Intimate Partner Violence
This study adapts and evaluates preliminary outcomes of the Mediational Intervention for Sensitizing Caregivers (MISC) for women and children of color who have survived domestic violence.
- Trial name
- MISC-IPV (NCT05948631)
- Testing
- MISC intervention, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Houston
Parenting, Adolescent Problem Behavior
Computerized Parenting Intervention
This study will evaluate a low-cost, low-intensity, computer-based model for delivering parenting skills to parents of adolescents in a community mental health clinic.
- Trial name
- NCT03751345
- Testing
- Parenting Wisely
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Oral Polio Vaccine
Use of mOPV1 in Routine Immunization in Pakistan.
Pakistan has uninterrupted circulation of polioviruses and this may threaten the entire global community. Bivalent OPV (bOPV), which protects against types 1 and 3, is used for routine immunization.
- Trial name
- mOPV1 (NCT04504539)
- Testing
- mOPV, bOPV, Full dose IPV
- Where
- Pakistan
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Aga Khan University