Clinical trials: Complex Care
Rare Diseases
FACE for Children With Rare Diseases
Children with ultra-rare or complex rare diseases are routinely excluded from research studies because of their conditions, creating a health disparity.
- Trial name
- FACE-Rare (NCT04855734)
- Testing
- FAmily CEntered (FACE) pACP Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
Wireless Vital Signs Monitoring System, Acutely Ill Complex and Poly-pathological Patients
Role of Wireless Monitoring in Internal Medicine Unit for Ongoing Assessment of Acute Instable Patients
The present study was planned to provide clinical data on the impact of acute and critically ill patients in Internal Medicine Unit activity and economic data enabling to quantify the relative cost of acute patients management…
- Conditions
- Wireless Vital Signs Monitoring System, Acutely Ill Complex and Poly-pathological Patients, Internal Medicine Unit Mission
- Trial name
- LiMS (NCT03050034)
- Testing
- WIN @ Hospital system, Traditional monitoring
- Where
- Italy
- Volunteers
- 296 people
- Sponsor
- Azienda Socio Sanitaria Territoriale del Garda
Ewing Sarcoma, Rhabdomyosarcoma
Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors
This research study is studying stereotactic body radiotherapy (SBRT) as a possible treatment for lung relapse of Ewing sarcoma, rhabdomyosarcoma, osteosarcoma, non-rhabdomyosarcoma soft tissue sarcoma, Wilms tumor or other…
- Conditions
- Ewing Sarcoma, Rhabdomyosarcoma, Wilms Tumor, Osteosarcoma
- Trial name
- NCT02581384
- Testing
- Stereotactic Body Radiotherapy (SBRT)
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Dana-Farber Cancer Institute
Postmenopausal Osteoporosis
Quality of Life in Postmenopausal Women With Osteoporosis
The researchers will evaluate the effectiveness of a complex intervention composed of multiple actions targeting primary care healthcare workers and postmenopausal women with osteoporosis by means of a quasi-experimental design…
- Trial name
- NCT03970902
- Testing
- Integrated Osteoporosis Care, Care As Usual
- Where
- Belgium
- Volunteers
- 239 people
- Sponsor
- University Ghent
Coagulation Protein Disorders, Blood Loss, Surgical
Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study)
Beriplex® P/N is made from human plasma (the liquid part of the blood) and contains the coagulation factors II, VII, IX and X which are important for blood clotting (coagulation).
- Conditions
- Coagulation Protein Disorders, Blood Loss, Surgical, Perioperative Care
- Trial name
- NCT01053169
- Testing
- Beriplex® P/N, Fresh Frozen Plasma (FFP) and Beriplex® P/N, Fresh Frozen Plasma
- Where
- 6 sites in United Kingdom
- Volunteers
- 445 people
- Sponsor
- CSL Behring
Fall, Pressure Ulcer
PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert
Inclusion criteria for study I and II is nurse aides, registered nurses and managers working in nursing homes who register in Senior Alert.
- Conditions
- Fall, Pressure Ulcer, Malnutrition, Oral Health
- Trial name
- NCT05308862
- Testing
- Care process for assessements of risks
- Where
- Sweden
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Malmö University
Chronic Conditions, Pediatric Intensive Care
Turkish Adaptation of a Sleep Screening Tool for Pediatric Complex Chronic Conditions
This study aims to adapt the Sleep Screening Scale for Children and Adolescents with Complex Chronic Conditions (SCAC) into Turkish and test its reliability and validity for this population.
- Conditions
- Chronic Conditions, Pediatric Intensive Care, Sleep Disorder (Disorder), Sleep
- Trial name
- SCAC (NCT07210476)
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people
- Sponsor
- Marmara University
Frailty
Supporting Uptake of Evidence for Physical Activity in Older Adults With Complex Health Care Needs
Physically frail older adults often have chronic conditions that contribute to a higher chance of them being limited in daily activities and becoming dependent.
- Trial name
- Moving_More (NCT06894914)
- Testing
- 24-hour Activity Counselling
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
PROM, Satisfaction, Patient
Assessment of the Humanisation of Care in Hospitals in Andalusia-Spain
Observational assessment through patient interviews of relational, structural and organisational aspects related to the humanisation of health care.
- Conditions
- PROM, Satisfaction, Patient, Satisfaction, Personal, Stress
- Trial name
- HUMANCUIDA (NCT06174844)
- Testing
- No intervention applied
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Chronic Respiratory Failure
Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting
The purpose of this study is to implement a standardized protocol to initiate nasal non-invasive ventilation with RAM nasal cannula (NIV/RAM-NC) with Trilogy mechanical ventilator at Children Memorial Hospital inpatient and…
- Trial name
- NCT03473171
- Testing
- Nasal non-invasive ventilation with RAM cannula
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center, Houston
Liver Cancer, Rhabdomyosarcoma
Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Patients may be considered if the cancer has come back, has not gone away after standard treatment or the patient cannot receive standard treatment.
- Conditions
- Liver Cancer, Rhabdomyosarcoma, Malignant Rhabdoid Tumor, Liposarcoma
- Trial name
- NCT04715191
- Testing
- CARE T cells
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor College of Medicine
Complex Congenital Heart Disease
Noninvasive Measurement of the Cerebral Autoregulation in Neonates and Infants With Complex Congenital Heart Disease
Feasibility of non-invasive cerebral autoregulation measurement at the PICU and impact of changes in oxygen supply
- Trial name
- NCT04810013
- Testing
- non-invasive measurement of cerebral autoregulation
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Unplanned Use of Health Care Services
Telehealth Nursing Intervention for Children With Complex Health Care Needs (CCHCN)
The overall objective of this study is to evaluate the effectiveness of a telehealth care coordination and case management nursing intervention for children with complex special health care needs.
- Trial name
- NCT01328353
- Testing
- telehealth plus aprn triage
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Minnesota
Data Accuracy, Agency
Empowerment Training for Personal Agency Development of Primary Health Care Workers
This study evaluates an Empowerment Agency Training (EAT) intervention within the SPHERES programme that aims to strengthen personal agency among workers in primary healthcare centers (Puskesmas) in Indonesia.
- Conditions
- Data Accuracy, Agency, Burnout, Service Evaluation
- Trial name
- NCT07509931
- Testing
- Empowerment Agency Training (EAT)
- Where
- 2 sites in Indonesia
- Volunteers
- 200 people
- Sponsor
- Oxford University Clinical Research Unit Indonesia
Antimicrobial Drug Resistance
A Complex Intervention to Promote Appropriate Antibiotic Use Among Rural Residents Based on the Metaphor-Embedded Integrated Behavioral Model
The study aims to address the question of how to provide effective health education on health topics with high medical specialisation (e.g.
- Trial name
- NCT06967766
- Testing
- health education based on the Metaphor-Embedded Integrated Behavioral Model
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bo Yan
Staph Aureus Methicillin Resistant Colonization
Study of 2% Chlorhexidine Gluconate-Impregnated Bath Cloths to Prevent MRSA Colonization in Complex Continuing Care
The purpose of this study is to determine whether daily bathing with 2% chlorhexidine gluconate-impregnated antiseptic cleanser (CHG) significantly reduces incidence of colonization of hospitalized patients with…
- Trial name
- NCT01717690
- Testing
- CHG antiseptic body cleanser
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Baycrest
Type 2 Diabetes Mellitus, Health Behavior
The Together on Diabetes Intervention - a Realist Evaluation
The Danish healthcare system is universal and free of charge for Danish citizens, as all healthcare services are financed by general taxes.
- Conditions
- Type 2 Diabetes Mellitus, Health Behavior, Delivery of Health Care
- Trial name
- NCT04722289
- Testing
- Together on Diabetes
- Volunteers
- 20 people
- Sponsor
- Center for Diabetes, Copenhagen Municipality
Medically Complex Children, Care Coordination
Improving Care for Children With Complex Needs
Seattle Children's Hospital (SCH), in collaboration with several health plans and Washington State Department of Social and Health Services developed the Comprehensive Case Management (CCM) program with the goal to reduce costs…
- Conditions
- Medically Complex Children, Care Coordination, Case Manager, Care Manager
- Trial name
- I3CN (NCT01587105)
- Testing
- Comprehensive Case Management Service
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Seattle Children's Hospital
Complex and Chronic Pluripathology
Case Management of Complex Pluripathology in Primary Care
Aims To assess the effect of the implementation of the Community Nurse Case Manager (CNCM) in the care of complex and pluripathological chronic patients (CPCP) with dependence, from Primary Care, on functional capacity, cognitive…
- Trial name
- ENGESCC (NCT06155591)
- Testing
- Community Nurse Case Manager (CNCM)
- Volunteers
- 212 people
- Sponsor
- José Ignacio Recio Rodriguez
Rare Diseases, Mitochondrial Diseases
A Multi-Dimensional Model of cAre and transItion for Patients With cOmplex RAre Diseases
Over the past century, the progress in biomedical sciences gave outstanding contributions to the understanding of human conditions, and even curing some of them.
- Conditions
- Rare Diseases, Mitochondrial Diseases, Muscular Dystrophies, Dysmorphic Disorder, Body
- Trial name
- AD-MAIORA (NCT07558213)
- Testing
- Etiopathogenetic diagnosis, Functional diagnosis
- Where
- Italy
- Volunteers
- 136 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS