Clinical trials: Complication Rate
Diabetic Nephropathy
Efficacy of Telmisartan and the Combination of Telmisartan and Ramipril in type1 Diabetes Patients With Nephropathy
Hypothesis: The angiotensin receptor blocker telmisartan is effective at reduction of albumin excretion rate(AER) in patients with type1 diabetes and micro or macroalbuminuria.
- Trial name
- START1DM (NCT00738660)
- Testing
- Telmisartan, Ramipril
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Peritoneal Dialysis
A Multi-center Prospective Cohort Study Based on Peritoneal Dialysis Telemedicine-assisted Platform
Increasing the proportion of patients on peritoneal dialysis (PD) may relieve the financial burden caused by the growing number of patients with end-stage renal disease (ESRD).
- Trial name
- PDTAP (NCT03571451)
- Where
- 27 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Peking University First Hospital
Implant Complication, Complication, Postoperative
Orthopaedic Implant Removal
The necessity of orthopedic implant removal is under intense discussion and even if it is performed as an elective procedure, the risk of complications is present.
- Conditions
- Implant Complication, Complication, Postoperative, Implant Site Infection
- Trial name
- NCT03164408
- Testing
- Orthopaedic Implant Removal
- Volunteers
- 1,545 people
- Sponsor
- Universitätsmedizin Mannheim
Tonsillectomy, Child
The CMCPCTH Research in Chinese Children
To obtain hemorrhage rate after coblation tonsillectomy, and to investigate risk factors of hemorrhage after coblation tonsillectomy in children.
- Conditions
- Tonsillectomy, Child, Postoperative Hemorrhage
- Trial name
- NCT05206799
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- Shanghai Children's Hospital
Acute Kidney Injury, Critically Ill Children
Iohexol for Measuring Renal Function
Approximately 25-35% of all children admitted to the paediatric intensive care unit (PICU) or neonatal intensive care unit (NICU) will develop Acute Kidney Injury (AKI) during the first seven days after admission.
- Trial name
- HERO (NCT03946345)
- Testing
- Iohexol Inj 300 MG/ML
- Where
- Netherlands
- Volunteers
- 105 people
- Sponsor
- Radboud University Medical Center
Anesthesia Awareness
Heart Rate Variability to Quantify General Anesthesia Depth
The shortage of anesthetic agents can lead to intraoperative awareness while overdosing can trigger severe intra and postoperative problems.
- Trial name
- NCT04788732
- Testing
- ECG and EEG monitoring
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Urethral Stricture
Urethral Stricture: A Comparison Between Jugal or Labial Graft Urethroplasty
Buccal mucosa urethroplasty is a current fashion in urethral stricture management. In our university centre (Hospital de Clínicas de Porto Alegre) is a common surgical treatment choice.
- Trial name
- NCT03973619
- Testing
- Labial Graft, Jugal Graft
- Volunteers
- 77 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Prematurity
Electrocardiography Versus Pulse Oximetry for Newborn Heart Rate Determination
The goal of this study is to compare the time required for accurate heart rate measurement of the preterm newborn when using pulse oximetry versus electrocardiography leads.
- Trial name
- NCT01256346
- Testing
- Apparatuses
- Where
- United States
- Sponsor
- University of Oklahoma
Emergence Delirium, Extubation Time
Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia
Dexmedetomidine (DEX) is safe and effective in reducing ED following sevoflurane anesthesia. The investigators intend to study the efficacy of DEX in reducing ED in children undergoing tonsillectomy with and without adenoidectomy…
- Conditions
- Emergence Delirium, Extubation Time, Heart Rate, Postoperative Analgesia
- Trial name
- NCT03131375
- Testing
- Dexmedetomidine, Normal saline, Bispectral index
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Orthodontic Appliance Complication
The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention
Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs).
- Trial name
- NCT04788550
- Testing
- Fluoridated toothpaste, fluoride varnish (5% sodium fluoride), CPP-ACP plus crème group
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Infant, Premature, Intubation, Intratracheal
Fentanyl and Rocuronium for Tracheal Intubation in Newborns
Tracheal intubation is a common and critical procedure in neonatal intensive care units (NICU). Despite its clinical importance, first-attempt success rates remain low (approximately 50%), and adverse events - including oxygen…
- Conditions
- Infant, Premature, Intubation, Intratracheal, Respiratory Distress Syndrome, Newborn, Apnea of Prematurity
- Trial name
- NEORIN (NCT07650552)
- Testing
- Rocuronium Bromide 10 MG/ML, Fentanyl 1 mcg/kg IV, single dose, administered before non-emergent tracheal intubation.
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- UEA - Universidade Do Estado Do Amazonas
Vesicoureteral Reflux
Determination of Voiding Patterns of Children With Vesicoureteral Reflux
Determine if the pattern of voiding differs in children with vesicoureteral reflux (VUR) compared to those who do not have VUR.
- Trial name
- NCT00186199
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gestational Diabetes Mellitus, Class A2
Failure Rate of GLyburide And Metformin Among Gestational Diabetics
A pragmatic, comparative effectiveness trial of glyburide versus metformin.
- Trial name
- GLAM (NCT03078725)
- Testing
- Glyburide, Metformin
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Other Preterm Infants
Monitoring of Vital Signs During Skin-to-skin Holding by Mothers of Their Preterm Babies
This observational study aims to monitor the vital sign changes in both mother and baby that occur during kangaroo care in preterm infants and to investigate any potential correlations between maternal measurement values and…
- Trial name
- NCT02231801
- Testing
- Mother-Infant Dyad
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Kangaroo-mother Care
Skin-to-skin Contact Between Premature Infant and Mother
Aim: To determine the effect of kangaroo mother care (KMC) on perfusion index, heart rate, and oxygen saturation in premature infants who were discharged early and admitted to the neonatal intensive care in the following days.
- Trial name
- NCT06380231
- Testing
- kangaroo mother care (KMC)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul Rumeli University
Perinatal Depression
Early Detection of Perinatal Depression With Wearable Technology
The goal of this feasibility study is to learn whether wearable devices and self-report surveys can help researchers better understand changes in mood during pregnancy and after birth in young pregnant individuals with a history…
- Trial name
- BLUESMAPPED (NCT07784244)
- Testing
- Oura Ring (Photoplethysmography-based wearable ring), EmbracePlus Watch (Electrodermal activity wristband sensor)
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Intubation, Pediatric, Intubation; Difficult or Failed
Validation of the POGO Score for Classification of Videolaryngoscopy in Children - Post-hoc Analysis of the PeDiAC Study
It has been assumed that the percentage of glottic opening (POGO) score might enhance the classification of videolaryngoscopic tracheal intubation by offering a more objective rating of glottic exposure but studies in children…
- Conditions
- Intubation, Pediatric, Intubation; Difficult or Failed, Airway Management, Airway Complication of Anesthesia
- Trial name
- POGO-KIDS (NCT07115407)
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pregnancy; Habitual Aborter, Weeks of Gestation 37 or More
Accuracy and Reliability of Fetal Heart Rate and Uterine Contraction Monitoring Method
Clinical Investigation Protocol for a study designed to determine the equivalence of the Monica AN24 monitor to Philips 50XM for fetal heart rate (FHR) and uterine contraction (UC) monitoring during labor.
- Trial name
- NCT01280357
- Testing
- Monica AN24 (K101081), Philips 50XM
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Healthcare Ltd
Heartfailure
Maximizing CRT Delivery by Using MultipolAr Coronary Sinus Lead FamiLy ACUITY® X4 - RALLY X4 Study
The objective of this study is to collect clinical data on safety and performance of ACUITY X4® leads when used in a standard clinical setting.
- Trial name
- RallyX4 (NCT02066467)
- Testing
- Left Ventricular lead implant: ACUITY X4® Lead Family
- Where
- 83 sites in Austria, Belgium and 16 more
- Volunteers
- 863 people
- Sponsor
- Boston Scientific Corporation