Clinical trials: Complication Rate
Cervical Cancer
Feasibility Study of the Xoft® Axxent® Electronic Brachytherapy System for the Treatment of Cervical Cancer
The purpose of this study is to evaluate the safety, performance and usability of the Xoft Axxent Electronic Brachytherapy System and Cervical Applicator as incorporated into the physician's current standard treatment practice…
- Trial name
- NCT01851772
- Testing
- Treatment with Electronic Brachytherapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Xoft, Inc.
Ankyloglossia, Tongue-tie
Healing Efficacy of Diode Laser in Lingual Frenectomy
This study aims to compare the wound healing efficacy and postoperative experiences between the 940 nm diode laser technique and the traditional electrosurgery method for treating ankyloglossia (tongue-tie) in children aged 3 to…
- Trial name
- NCT07557875
- Testing
- Lingual Frenectomy using 940nm Diode Laser, Lingual Frenectomy using High-frequency Electrosurgery
- Where
- 2 sites in Vietnam
- Volunteers
- 53 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Fetal Heart Rate Abnormalities, Respiratory Depression
Safer Births - Reducing Perinatal Mortality
Safer Births is a research and development collaboration to establish new knowledge and new innovative products to better equip and increase competence of health workers for safer births and increased newborn survival worldwide.
- Conditions
- Fetal Heart Rate Abnormalities, Respiratory Depression, Birth Asphyxia, Neonatal Resuscitation
- Trial name
- NCT01869582
- Testing
- Fetoscope, Fetal heart rate, Upright Resuscitator, Resuscitation, Doppler, Fetal heart rate
- Where
- 2 sites in Tanzania
- Volunteers
- 20,000 people
- Sponsor
- Helse Stavanger HF
Infertility, Miscarriage
Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689428
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Mechanical Ventilation Pressure High, Bariatric Surgery Candidate
Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome).
- Trial name
- NCT06168162
- Testing
- titated PEEP to best static compliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Type1diabetes, Type1 Diabetes Mellitus
Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
Over 1.25 million Americans have Type 1 Diabetes (T1D), increasing risk for early death from cardiovascular disease (CVD). Despite advances in glycemic and blood pressure control, a child diagnosed with T1D is expected to live up…
- Conditions
- Type1diabetes, Type1 Diabetes Mellitus, Diabetic Kidney Disease, Juvenile Diabetes
- Trial name
- COFFEE (NCT03878277)
- Testing
- Starbucks® Cold brew - 325ml bottle
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Congenital Adrenal Hyperplasia, Exercise Capacity
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH
Congenital Adrenal Hyperplesia (CAH) is a group of automosal recessive disorders that develop due to a deficiency of one of the five enyzmes necessary for cortisol synthesis in the adrenal cortex.
- Conditions
- Congenital Adrenal Hyperplasia, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- NCT06449456
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Severe Pre-eclampsia, Magnesium Level
Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy
Comparison of the magnesium level in difference continuous rate in women who were diagnosed severe pre-eclampsia obese
- Trial name
- NCT03661775
- Testing
- Magnesium sulfate administration
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease
To collect characteristics of patients with ADPKD across a broad population, over time to better understand disease progression (signs, symptoms and outcomes).
- Trial name
- OVERTURE (NCT01430494)
- Where
- 266 sites in United States, Argentina and 18 more
- Volunteers
- 3,409 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Kidney Disease
Assessment of Serum Cystatin C as a Marker of Kidney Function in Children
The purpose of this study is to assess serum cystatin C as a marker of kidney function (glomerular filtration rate, GFR) in children aged 2-14.
- Trial name
- NCT00300066
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Cervical Cancer
Single Application Brachytherapy in Cervical Cancer
The purpose of the study is to evaluate safety and feasibility of single brachytherapy application with dose delivery in multiple fractions.
- Trial name
- NCT03110497
- Testing
- Single application multi-fraction brachytherapy
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Tata Memorial Hospital
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Respiratory Distress Syndrome, Prematurity
Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants.
Background Preterm infants often need respiratory support. HFNV is a non-invasive method with benefits over CPAP, such as reduced nasal trauma and improved feeding. Aim Study the impact of low (2 LPM) vs.
- Conditions
- Respiratory Distress Syndrome, Prematurity, Non Invasive Ventilation
- Trial name
- NCT06622902
- Testing
- change flow from 6 to 2 LPM. Follow TcCO2 for 3 hours, change flow from 2 to 6 LPM. Follow TcCO2 for 3h
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Rambam Health Care Campus
Diabetic Foot, Amputation
Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort Study
This study explored the pattern and type of amputations performed on patients with diabetic foot who were admitted to our institution, as well as the 7-year mortality rate of patients with diabetic foot at the same institution.
- Trial name
- NCT05123157
- Testing
- NO intervention
- Where
- Saudi Arabia
- Volunteers
- 358 people
- Sponsor
- King Abdulaziz University
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Preterm, Monitoring
The Use of the Bambi-Belt in Exteremly Preterm Infants: an Implementation Study.
This observational, non-interventional cohort study evaluates the clinical use of the Bambi Belt-a CE-certified, wireless device for non-invasive heart rate and respiration monitoring-in extremely preterm infants (<26 weeks…
- Trial name
- BB-EP (NCT07061366)
- Where
- 2 sites in Netherlands
- Volunteers
- 15 people
- Sponsor
- Maxima Medical Center
Preterm Infant
Executive Functions and Preterm Children in 11 to 12 Year Old
Preterm children have a high risk for neurodevelopmental impairments. The impact on motor functions and neurosensory functions is demonstrated but the incidence of executive functions is not described for preterm infants.
- Trial name
- NCT03700619
- Testing
- BRIEF parental survey
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Nantes University Hospital
Renal Stone, Retrograde Intrarenal Surgery
Evaluation of Retrograde Intrarenal Surgery Results and Stone-free Rate in Children With Kidney Stones
There is a global increase in the prevalence of urolithiasis in children attributed to lifestyle changes, dietary habits, climate changes, childhood obesity, and the wider availability of ultrasonography.
- Trial name
- NCT06138704
- Testing
- Retrograde Intrarenal Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ankara City Hospital Bilkent
Kidney Disease
Evaluation of New Test Method to Measure Kidney Function
This study will test the accuracy of a new "Fast GFR" (glomerular filtration rate) test to evaluate kidney function. Accurate assessment of kidney function is important in many clinical situations, including detecting kidney…
- Trial name
- NCT00026715
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center