Clinical trials: Complications; Arthroplasty
Cardiovascular Surgical Procedures, Arthroplasty, Replacement
Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
The specific aims are to determine the incidence of medication errors related to antimicrobial prophylaxis for cardiovascular surgery, joint replacement surgery, and hysterectomies across a heterogeneous sample of hospitals…
- Conditions
- Cardiovascular Surgical Procedures, Arthroplasty, Replacement, Hysterectomy
- Trial name
- NCT00114036
- Testing
- Quality improvement strategies
- Where
- 3 sites in United States
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Knee Arthroplasty, Postoperative Complications
Increased Perioperative Communication Program in Knee Arthroplasty
Total knee replacement (TKA) is a surgical procedure to increase the function of the knee joint. However, in the postoperative period, it takes a long time for patients to gain independence and adapt to daily life, and they need…
- Trial name
- NCT06130813
- Testing
- increased perioperative communication program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Postoperative Pain, Analgesic Efficacy
Local Anesthetic in Total Knee Arthroplasty (TKA): Volume Versus Concentration
In a randomized, double-blind, cross-over trial, 48 patients scheduled for total knee arthroplasty with placement of an intracapsular catheter will be randomized to receive bolus injection of ropivacaine in high volume/low…
- Trial name
- NCT01012232
- Testing
- 20 mL ropivacaine 5 mg/mL, 10 mL ropivacaine 10 mg/mL
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Lundbeck Foundation
Postoperative Pain
Arthroplasty Inflammation Prophylaxis With Celecoxib
This double blinded, placebo controlled, study seeks to determine the efficacy of preoperative anti-inflammatory therapy on the reduction of postoperative pain in knee arthroplasty surgery.
- Trial name
- NCT00533247
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zanbilowicz, Adam, DPM MS
Postoperative Pain, Hip Arthroplasty
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Hip Arthroplasty
High-volume infiltration analgesia may be effective in postoperative pain management following total hip arthroplasty. In this randomized, double-blind trial patients undergoing bilateral hip arthoplasty are randomized to receive…
- Trial name
- NCT00864409
- Testing
- ropivacaine 0,2%, saline.9%
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Hvidovre University Hospital
Knee Arthropathy, Postoperative Pain
IPACK Block After Total Knee Arthroplasty
Adductor canal block (ACB) is a peripheral nerve blockade technique that provides good pain control in patients undergoing total knee arthroplasty (TKA) which however does not relieve posterior knee pain.
- Trial name
- NCT04295421
- Testing
- adductor canal block, IPACK block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Arthroplasty, Hip Replacement, Infection, Postoperative Wound
Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery
This study will assess the efficacy of two of the most commonly used surgical skin-preparation solutions: Chloraprep (chlorhexidine-alcohol) and Duraprep (iodine-alcohol) at eliminating bacteria from the hip site by evaluating…
- Trial name
- NCT03393819
- Testing
- DuraPrep, ChloraPrep
- Volunteers
- 105 people
- Sponsor
- Lakehead University
Postoperative Pain, Analgesia
Evaluation of Dexketoprofen in Total Knee Arthroplasty
Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions. Dexketoprofen is a new NSAID treating acute postoperative pain.
- Trial name
- NCT04161690
- Testing
- Dexketoprofen Trometamol, Ropivacaine Hydrochloride 7.5 MG/ML
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KAT General Hospital
Arthroplasty Complications, Inflammatory Response
Effects of Navigation Versus Conventional Total Knee Arthroplasty on the Levels of Inflammation Markers
Total knee arthroplasty (TKA) is a well-established modality for the treatment of advanced knee osteoarthritis with high satisfaction rate.
- Trial name
- NCT03163888
- Testing
- Navigation TKR
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Hyperglycemia
Postoperative Hyperglycemia After Knee Primary Knee Arthroplasty Surgery
Patients in three hospitals in Sweden who will have knee arthroplasty surgery for the first time are invited to participate in the study, approximately 2000 patients.
- Trial name
- NCT03830931
- Where
- Sweden
- Volunteers
- 1,448 people
- Sponsor
- Lund University
Total Knee Arthroplasty
Compression Bandage in Local Infiltration Analgesia Afte Total Knee Arthroplasty
purpose: to determine wether a compression bandage prolongs analgesia of local infiltration analgesia after total knee arthroplasty
- Trial name
- NCT00485212
- Testing
- compression bandage
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Arthroplasty Complications
Outcome of Total Hip Replacement in Patients With Chronic Renal Disease
the study aims to determine rate of mortality and morbidity after total hip replacement in patients with chronic kidney diseases and incidence of periprosthetic joint infection in these patients.
- Trial name
- NCT03522285
- Testing
- investigation: erythrocyte sedimentation rate
- Volunteers
- 30 people
- Sponsor
- Assiut University
Preoperative Period, Nutritional Status
Preoperative Nutritional Status in Patients Undergoing Elective Total Knee Arthroplasty and In-hospital Postoperative Complications
Malnutrition has long been linked to postoperative complications and adverse outcomes in a variety of surgical fields , such as increased susceptibility to infection, delayed wound healing, and increased frequency of decubitus…
- Conditions
- Preoperative Period, Nutritional Status, Arthroplasty Knee
- Trial name
- NUTR TKA (NCT03549962)
- Testing
- TKA
- Where
- 2 sites in Hong Kong
- Volunteers
- 626 people
- Sponsor
- Chinese University of Hong Kong
Ototoxic Hearing Loss, Cobalt Poisoning
Ototoxicity in Patients With MoM Hip Bearings
The goal of this observational study is to learn about ototoxicity in patients with a MoM hip arthroplasty. The main question it aims to answer is: What is the prevalence of hearing loss in patients with high and low plasma metal…
- Conditions
- Ototoxic Hearing Loss, Cobalt Poisoning, Chromium Causing Toxic Effect, Arthroplasty Complications
- Trial name
- GODMOTHER (NCT06885411)
- Testing
- metal-on-metal hip arthroplasty
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Reinier Haga Orthopedisch Centrum
Arthroplasty, Replacement, Knee
Intraarticular Analgesia After Total Knee Arthroplasty, a Randomised Study
The study aims to compare two different kinds of pain treatment after total knee replacement (operation with artificial knee joint): 1) a large local injection in and around the knee, supplemented with injection the day after, or…
- Trial name
- NCT00269529
- Testing
- femoral nerve block, knee infiltration and injection via catheter
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Shoulder Arthritis, Blood Loss, Surgical
Effect of TXA on Blood Loss in Reverse Total Shoulder Arthroplasty
Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that has been well studied and routinely used for hip and knee arthroplasty.
- Conditions
- Shoulder Arthritis, Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
- Trial name
- NCT06638749
- Testing
- Tranexamic Acid, Normal Saline
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Knee Arthropathy
Effect of NLR and MPV on Early Postoperative Outcome in Lower Extremity Arthroplasty Operations
In the planned study the investigators want to evaluate the relation between postoperative complications and minor/ major morbidities, mortality and Mean Platelet Volume (MPV) and Neutrophil/ lymphocyte (N/L) ratio.
- Trial name
- NCT03148951
- Where
- Turkey (Türkiye)
- Volunteers
- 754 people
- Sponsor
- Akdeniz University
Prosthetic Joint Infection, Prosthetic Infection
Calprotectin in Chronic Prosthetic Joint Infection
A bacterial infection of an artificial joint is a serious complication that often requires additional surgery to exchange the arthroplasty.
- Conditions
- Prosthetic Joint Infection, Prosthetic Infection, Arthroplasty Complications
- Trial name
- NCT05060952
- Testing
- Calprotectin Lateral Flow Test
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Knee Osteoarthritis, Vitamin D Deficiency
Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preoperative Rehabilitation in Patients Before Knee Arthroplasty.
Prospective randomized study of 150 patients qualified for knee arthroplasty between 2015 and 2017. Patients were randomized into 3 groups receiving vitamin D and calcium supplementation, increased protein supply and preoperative…
- Conditions
- Knee Osteoarthritis, Vitamin D Deficiency, Pain, Postoperative, Arthropathy of Knee
- Trial name
- NCT04291833
- Testing
- Intervention group 1, Intervention group 2, Control group 0
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Jagiellonian University