Clinical trials: Comprehension
Anxiety
Improving Patient Understanding of the Surgical Hospital Experience: Use of YouTube Video Playlist
This prospective randomized pilot clinical trial studied the effect on preoperative anxiety of watching a series of YouTube videos designed to create a virtual hospital experience for patients undergoing primary total hip and…
- Trial name
- NCT02546180
- Testing
- Viewing YouTube videos, Standard preoperative education
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diarrhea, Infantile, Infection Gastrointestinal
PAthogen Transmission and Health Outcome Models of Enteric Disease
The objective of the PATHOME study is to (1) develop statistical and computational methods for examining a complex disease system of interactions between and amongst children, animals, the environment, and enteric pathogens and…
- Conditions
- Diarrhea, Infantile, Infection Gastrointestinal, Stunting, Wasting
- Trial name
- PATHOME (NCT05322655)
- Where
- Kenya
- Volunteers
- 286 people
- Sponsor
- State University of New York at Buffalo
Chronic Disease
Qualitative Phenomenological Study on Videoconferencing Therapeutic Education
Therapeutic patient education (TPE) is one of the mechanisms that make patients with chronic disease as competent as possible to manage illness and treatment by helping them to be autonomous and responsible for their…
- Trial name
- Visio ETP (NCT05378958)
- Testing
- Individual interview
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
RETT Syndrome With Proven MECP2 Mutation
Osteoporosis in RETT Syndrome
Based on our clinical observations, many girls with RETT syndrome, a severe neuro-developmental encephalopathy, suffer from osteoporosis which can appear at a very early age (before age 10) and can lead to fractures, pain and a…
- Trial name
- OSRETT (NCT02110797)
- Testing
- biological markers and evaluation of the mineral density at the lumber spine using DEXA
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stress, Diaplegia
Understanding Parental Stress and Quality of Life in Families of Children With Diplegic Cerebral Palsy: Key Influencing Factors
PURPOSE: To estimate the relationships between the child, parents, and family factors and parent stress and QoL among parents of children with diplegic CP.
- Conditions
- Stress, Diaplegia, Cerebral Palsy
- Trial name
- CP (NCT06516107)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sinai University
Nicotine Labeling for E-cigarettes
Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes
Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing and validating two new types of labels for the nicotine in vaping…
- Trial name
- NCT07553585
- Testing
- Updated Labeling
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
Heart Diseases
Database of Tissue Samples to Understand the Inflammatory Response After Cardiac Surgery
The aim of this study is to collect non-individual related blood samples for the compelling of a unique database of tissue samples to understand the inflammatory responds after cardiac surgery on an on-going basis.
- Trial name
- NCT02488876
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- RWTH Aachen University
Informed Consent
Patients' Comprehension and Internalization of Operative Consent Form
This is a prospective pilot study conducted within otolaryngology (ENT) clinics in a tertiary hospital between July and December 2016.
- Trial name
- NCT04627597
- Volunteers
- 22 people
- Sponsor
- Singapore General Hospital
Atrial Fibrillation
Impact of the Information Follow-up Given to Patients on Their Disease Understanding and Therapeutic Adherence in Patients Under Direct Oral Anticoagulants and With Atrial Fibrillation in a Cardiology Department
The primary objective of this study is to measure in patients addressed for Atrial Fibrillation (AF) in the Cardiology-Electrophysiology and Cardiac Stimulation Department of Bordeaux hospital, the impact of a specialized nurse…
- Trial name
- RYTHM-UP AOD (NCT03645564)
- Testing
- Specialized nurse consultation
- Where
- France
- Volunteers
- 221 people
- Sponsor
- University Hospital, Bordeaux
Disabilities Multiple
End Diagnostic Overshadowing
The goal of this study is to address the critical issue of diagnostic overshadowing by applying the Collective Impact Model40 to co-produce our End Diagnostic Overshadowing program with academic, health systems, health…
- Trial name
- EDO (NCT06608758)
- Testing
- Electonic health record prompts with education, Standard of care
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Hemophilia A With Inhibitor
Understanding Treatment Outcomes and Immunologic Mechanisms in Altuviiio Immune Tolerance Induction
The goal of this clinical trial is to learn how well Altuviiio (efanesoctacog alpha) works for Immune Tolerance Induction (ITI) while using Hemlibra (emicizumab) to prevent bleeds.
- Trial name
- UTILITI (NCT07158606)
- Testing
- efanesoctacog alpha, Emicizumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Versiti Blood Health
Psoriasis, Covid19
PsoVac: Educational Needs re Vaccines for Biologic Patients With Psoriasis
To determine if there is a need for further education on vaccines with psoriasis patients who are on a biologic. In regards to the COVID-19, it is important that psoriasis patients - whether on a biologic or not - understand…
- Trial name
- NCT04513847
- Where
- Canada
- Volunteers
- 661 people
- Sponsor
- Dermatrials Research
Diabetes Mellitus, Type 1 Diabetes
Achieving Health in Emerging Adults With Diabetes (AHEAD) Program: A Clinical Trial Designed to Understand if Participation in a Clinical Program Developed Specifically to Support Emerging Adults With Type 1 Diabetes Leads to Improved Diabetes Outcomes.
The goal of this study is to determine whether the Achieving Health in Emerging Adults with Diabetes (AHEAD) Program helps emerging adults with type 1 diabetes improve their blood glucose management during the transition from…
- Trial name
- AHEAD Program (NCT07292558)
- Testing
- AHEAD Program
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- University of British Columbia
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Neural Mechanisms of Sensory Processing Anomalies
To assess sensory processing anomalies in neurotypical children, children with autism spectrum disorder, and attention-deficit hyperactivity disorder, particularly within the vibrotactile and auditory sensory modalities.
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Sensory Processing Disorder
- Trial name
- NCT06234033
- Testing
- Discrimination Acuity test, Transiently Evoked Otoacoustic Emission, Questionnaires
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Aalborg University
Colon Cancer, Gastric Cancer
A Novel Patient Engagement Platform Among Patients With Gastrointestinal Malignancies
A randomized control trial to evaluate the feasibility of implementing a patient educational platform (PEP) for patients with gastrointestinal malignancies undergoing active chemotherapy treatment.
- Conditions
- Colon Cancer, Gastric Cancer, Pancreas Cancer, Rectal Cancer
- Trial name
- NCT04316078
- Testing
- patient engagement platform
- Where
- Israel
- Volunteers
- 126 people
- Sponsor
- Sheba Medical Center
Informed Consent
Informed Consent and Clinical Trials
To understand the patients' meaning of the informed consent process in clinical trials. Objective of the study is: to assess, in a cohort of subjects included in clinical trials, whether the information and the informed Consent…
- Trial name
- NCT01635842
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Azienda Usl di Bologna
Wiskott-Aldrich Syndrome
Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)
WAS is a rare primary immune deficiency disease caused by genetic mutation and is more common in males than females. The purpose of this study is to understand experiences of WAS subjects and caregivers to identify important…
- Trial name
- NCT03399461
- Testing
- Patient Interview guide, Caregiver interview guide, Sociodemographic questionnaire
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- GlaxoSmithKline
Breast Neoplasms
A Study to Understand About the Study Medicine Palbociclib in Breast Cancer Patients After it is Out in the Japanese Market
The purpose of the study is to: compare the chances of getting interstitial lung disease (ILD) in new users of palbociclib plus fulvestrant to new users of fulvestrant alone (using data from before palbociclib was out in the…
- Trial name
- NCT07096024
- Testing
- palbociclib plus fulvestrant, fulvestrant
- Where
- United States
- Volunteers
- 95,637 people
- Sponsor
- Pfizer
Generalized Arterial Calcification in Infancy, Autosomal Recessive Hypophosphatemic Rickets Type 2
Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency
To date, the investigators lack characterization of, the burden of, and the systemic progression of disease in ENPP1 deficiency and ABCC6 deficiency from a patient and/or parent perspective.
- Trial name
- NCT04372446
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Inozyme Pharma