Clinical trials: Condition
Childhood Obesity, Bariatric Surgery Candidate
Validation of Circulating Endothelial Cells and Microparticles in Youth
Identification and validation of early chronic disease biomarkers in children is of paramount importance especially in the burgeoning arena of pediatric obesity research.
- Trial name
- NCT01508598
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- University of Minnesota
Kidney Failure, Acute
Modalities of Renal Replacement Therapy in Pediatric Acute Kidney Injury
Limited prospective data is available to compare morbidity and mortality between renal replacement modalities in pediatric acute renal failure.
- Trial name
- EPURE (NCT01569698)
- Testing
- acute extra renal replacement therapy
- Where
- 19 sites in Canada, France and 1 more
- Volunteers
- 310 people
- Sponsor
- Rennes University Hospital
Postoperative Pain
Laryngoscope Force During Suspension for Adenotonsillectomy
Suspension laryngoscopy is a common procedure during adenoteonsillectomy (removal of adenoids and tonsils), that consists of extending the patient's neck to allow better visualization of the tonsils.
- Trial name
- NCT06115798
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pediatric Obesity, Insulin Resistance
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
The primary objective of this randomized, parallel group, double-blind, placebo-controlled study is to determine whether treatment with metformin enhances insulin sensitivity in a group of ethnically diverse obese…
- Conditions
- Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
- Trial name
- NCT00667498
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Prevention of Venous Thromboembolism, Congenital Heart Disease
An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure
This is an observational study in which the data from children with congenital heart disease will be collected and studied. These children will include those who are prescribed rivaroxaban by their doctors after a heart surgery…
- Conditions
- Prevention of Venous Thromboembolism, Congenital Heart Disease, Fontan Procedure, Children
- Trial name
- NCT06193863
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Japan
- Volunteers
- 61 people
- Sponsor
- Bayer
Autism Spectrum Disorder (ASD), Pain Perception
Quantitative Sensory Testing to Study Pain Perception in Autism
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum.
- Trial name
- PPiA (NCT06659731)
- Testing
- Quantitative Sensory testing (QST), EEG
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Leukemia
Comparison of Laboratory Test Results of Minimal-Residual Disease in Samples From Patients With Acute Myeloid Leukemia
RATIONALE: Diagnostic procedures that find residual disease may help predict if the disease will come back in patients diagnosed with acute myeloid leukemia.
- Trial name
- NCT01498302
- Testing
- diagnostic laboratory biomarker analysis, flow cytometry
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Iron Deficiency, Anemia
Prevention of Iron Deficiency in 2nd Year of Life
Healthy babies(age 8-18 months) following a routine blood count, with no anemia or iron deficiency, will be randomly placed in two groups.
- Trial name
- NCT00479102
- Testing
- Ferripel-3 - iron polysaccharide complex for prevention
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Behavior
An Assessment of SAFE (Swift Accountable Fair Enforcement) in Cochise County
This is a Cochise County experiment with innovative probation supervision practices. Subjects are assigned to one of three supervision conditions.
- Trial name
- NCT01359137
- Testing
- Probation as usual, Deferred Jail, Arizona's SAFE
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Pepperdine University
Type2 Diabetes, Gestational Diabetes
Metabolic Risk and Life Style Factors in Women With Previous Gestational Diabetes Mellitus (GDM)
Women with previous Gestational Diabetes Mellitus (GDM) are characterized by several metabolic abnormalities i.e. insulin resistance, beta-cell dysfunction and increased risk of later Diabetes Mellitus (DM).
- Conditions
- Type2 Diabetes, Gestational Diabetes, Life Style
- Trial name
- NCT03050645
- Where
- Denmark
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia
Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome
Bronchopulmonary Dysplasia (BPD) is a multi-factorial disease process that is the end result of an immature, surfactant deficient lung that has been exposed to hyperoxia, mechanical ventilation and infection.
- Trial name
- NCT01941745
- Testing
- Half normal saline, Low Dose rhCC10, High dose rhCC10
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Tufts Medical Center
Infertility, Female
Heated and Non Heated Ovarian Aspiration Needle Protocol
The success of IVF is influenced by factors as cause of infertility and age. Furthermore, there is a large influence of external factors, from the laboratory environment, handling and cultivation of gametes and embryos.
- Trial name
- NCT05683639
- Testing
- warming of the follicular aspiration needle
- Where
- Brazil
- Volunteers
- 179 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Atlantoaxial Dislocation, Treatment
A Study on Diagnosis and Treatment Strategies for Atlantoaxial Dislocation
The most effective treatment for atlantoaxial dislocation is surgical treatment, with the principle of achieving reduction, reconstruction, and fusion of the atlantoaxial joint.
- Conditions
- Atlantoaxial Dislocation, Treatment, Diagnostic
- Trial name
- NCT06233539
- Testing
- Observational research without intervention
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Peking University Third Hospital
Type 1 Diabetes
Evaluating the InPen in Pediatric Type 1 Diabetes
Type 1 Diabetes (T1D) is the most common form of diabetes affecting children, requiring lifelong administration of insulin to prevent complications.
- Trial name
- EMPoWER (NCT05515939)
- Testing
- InPen Insulin Pen
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Wayne State University
Diabetes Mellitus Type 2
A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes
The purpose of this study is to assess the potential of BMS-986036 for treatment obese adults with type-2 diabetes.
- Trial name
- NCT02097277
- Testing
- BMS-986036
- Where
- 16 sites in United States, Canada
- Volunteers
- 219 people
- Sponsor
- Bristol-Myers Squibb
Pulsatile Tinnitus
The Recurrence Mechanism of Venous Tinnitus After Boney Wall Reconstruction Based on Multimodal Imaging and Multiphysics Coupling
Venous tinnitus (VT) is seriously affecting the quality of life of five million patients in China. Bony wall reconstruction is the main treatment method, but the postoperative recurrence rate exceeds 30%, and the specific…
- Trial name
- NCT05856175
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Aneurysm
Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms
Thoracic aortic aneurysms (TAA) are considered "silent killers" because they scarcely display any symptomatology, but are correlated with significant mortality and morbidity.
- Trial name
- NCT04224675
- Testing
- Atenolol
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Onassis Cardiac Surgery Centre
Supraventricular Tachycardia
Sevoflurane and Isoflurane for RF or Cryo Ablation in Children.
In children, radiofrequency catheter ablation (RFCA) or cryoablation are highly effective treatments for supraventricular tachycardia treatment.
- Trial name
- NCT01216501
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Schneider Children's Medical Center, Israel
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
The purpose of this study is to pilot the use of Insulin-Like Growth Factor-1 (IGF-1) treatment in 22q13 Deletion Syndrome (Phelan-McDermid Syndrome) caused by SHANK3 gene deficiency in order to evaluate safety, tolerability, and…
- Trial name
- NCT01525901
- Testing
- Insulin-Like Growth Factor-1 (IGF-1), Normal saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Biotin Deficiency, Optic Neuropathy
BIOtinidase Test In Optic-Neuropathy
Biotinidase is an enzyme that recycles biotin, a water-soluble vitamin essential as a coenzyme for four carboxylases that are involved in gluconeogenesis, fatty acid synthesis, and in the catabolism of several branch-chain amino…
- Trial name
- BIOTIN (NCT03268681)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
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