Clinical trials: Condition
Peripheral Arterial Disease
Treadmill Exercise and GM-CSF Study to Improving Functioning in Peripheral Artery Disease (PAD)
The PROPEL study will test the hypothesis that GM-CSF combined with supervised treadmill exercise will significantly improve functional performance in patients with PAD more than GM-CSF alone or supervised treadmill exercise…
- Trial name
- PROPEL (NCT01408901)
- Testing
- Supervised Treadmill Exercise Therapy, Health education sessions (Control), granulocyte macrophage colony stimulating factor (GM-CSF)
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Snoring
Investigating Reaction Time Among Children Who Snore
The investigators feel that children who have OSA or sleep-disordered breathing may have a different reaction time than normal variants. Children who have OSA are known to have behavioral and sleep patterns that are different.
- Trial name
- NCT02053012
- Testing
- PVT-192
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Vidya Raman
Transfusion-dependent Anemia
Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload
This was a randomized, open-label, multicenter, two arm, phase II study to evaluate treatment compliance and change in serum ferritin of a deferasirox granule formulation and a deferasirox dispersible tablet (DT) formulation in…
- Trial name
- NCT02435212
- Testing
- Deferasirox granule formulation, Deferasirox DT formulation
- Where
- 43 sites in United States, Belgium and 15 more
- Volunteers
- 224 people
- Sponsor
- Novartis Pharmaceuticals
Reversible Pulpitis
TheraCal PT vs. Formocresol in Primary Molar Pulpotomies
This prospective, randomized, parallel-group clinical trial evaluated the 12-month clinical and radiographic success rates of TheraCal PT versus formocresol in primary molar vital pulpotomies among 50 children aged 5 to 8 years.
- Trial name
- NCT07864181
- Testing
- Dual cured resin modified
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Hama University
Food Allergy Suspected, Food Allergy Proved
Association Between Asthma and Food Allergy
Prevalences of food allergies and asthma increased in the population during the last decades. These two pathologies, responsible for a real burden, are often associated and are to be considered as comorbidities; this aspect is…
- Trial name
- AAAli (NCT02884583)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Lung Cancer
Percutaneous Thermal Ablation in Lung Tumors
Lung cancer has a high incidence globally, with Egypt having it as the third most common and most lethal cancer, affecting 16.9% of males and 3.8% of females.
- Trial name
- Radiofrequency (NCT06891183)
- Testing
- Percutaneous thermal ablation of lung tumors
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Aplastic Anemia
Anti-thymocyte Globulin and Cyclosporine as First-Line Therapy in Treating Patients With Severe Aplastic Anemia
RATIONALE: Immunosuppressive therapies, such as anti-thymocyte globulin and cyclosporine, may improve bone marrow function and increase blood cell counts.
- Trial name
- NCT01231841
- Testing
- cyclosporine, anti-thymocyte globulin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Vaccination; Infection, Covid19
Risk of COVID-19 Infection After Vaccination
The purpose of this observational nationwide study is to evaluate the effects of three different COVID-19 vaccines for the outcome of different severities of incident COVID infection.
- Trial name
- NCT04848441
- Testing
- The COVID-19 vaccines BNT162b2, mRNA-1273 and ChAdOx1
- Volunteers
- 2,000,000 people
- Sponsor
- Umeå University
Adolescent Obesity
The Effect of Time-Restricted Feeding on Body Composition and Some Metabolic Parameters in Obese Adolescents
Obesity is now recognized as a serious public health problem. It is known that obesity seen in adolescence is largely carried over to adulthood.
- Trial name
- NCT06616454
- Testing
- Intervention group - Time restricted feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sümeyra Başar
Preeclampsia
Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia
The hypothesis of this study is that many plasma proteins are altered in concentration and structure in preeclampsia and the elucidation of these alterations will add to the poorly understood pathophysiology of preeclampsia.
- Trial name
- NCT00719654
- Where
- United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder, Aggressive Behaviour
Reintegrating Children Living at Landfills in Burundi Into Society by Means of a Comprehensive Family Program Addressing Maltreatment and Mental Health Symptoms
Children living at the landfills of Bujumbura are often exposed to maltreatment, including emotional neglect and physical abuse, and traumatic experiences. Furthermore, they grow up in severe poverty.
- Conditions
- Posttraumatic Stress Disorder, Aggressive Behaviour, Parental Maltreatment, Days Spent at the Landfill
- Trial name
- NCT03846154
- Testing
- Comprehensive family intervention including individual sessions of FORNET
- Where
- Burundi
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Schizophrenia, Paranoid, Schizophrenia, Disorganized
Fixed Dose Efficacy and Safety Study of Asenapine for the Treatment of Schizophrenia in Adolescents (P05896)
This study is designed to evaluate whether asenapine, which is approved by the United States Food and Drug Administration (US FDA) for acute treatment of schizophrenia in adults, is also effective in adolescents with…
- Conditions
- Schizophrenia, Paranoid, Schizophrenia, Disorganized, Schizophrenia, Undifferentiated
- Trial name
- NCT01190254
- Testing
- asenapine 2.5 mg, asenapine 5.0 mg
- Volunteers
- 306 people
- Sponsor
- Organon and Co
Diffuse Large B-cell Lymphoma
Treatment Resistance Related With Gene Expression Profile of Diffuse Large B-cell Lymphoma
The investigators perform a retrospective microarray gene expression profiling study of FFPE from a cohort of DLBCL patients with whole genome cDNA mediated Annealing Selection and Ligation (WG-DASL) assay.
- Trial name
- NCT01606605
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Acute Kidney Injury, Covid19
Renal Involvement in Hospitalized Children With COVID-19
Covid-19 is an important human and animal pathogen, it mostly causes respiratory and gastrointestinal symptoms. Clinical features range from a common cold to severe diseases such as severe acute respiratory distress syndrome…
- Conditions
- Acute Kidney Injury, Covid19, Renal Dysfunction, Coronavirus Infection
- Trial name
- RIHCC (NCT04788394)
- Testing
- data review, data comparing
- Where
- Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
Type 1 Diabetes Mellitus, Stage 2 Type 1 Diabetes
Information, Follow-up and Early Diagnosis of Children at Risk for Type 1 Diabetes
The aim is to investigate whether screening for islet autoantibodies, regular follow-up, and increased knowledge in families about the progression of the disease in children at high genetic risk or with single or multiple islet…
- Conditions
- Type 1 Diabetes Mellitus, Stage 2 Type 1 Diabetes, Stage 1 Type 1 Diabetes, Stage 3 Type 1 Diabetes
- Trial name
- iT1D (NCT06676566)
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
Ulcerative Colitis, Crohn's Disease
A Phase I Study of Etrolizumab Followed by Open-Label Extension and Safety Monitoring in Pediatric Patients With Moderate to Severe Ulcerative Colitis or Moderate to Severe Crohn's Disease
This study will evaluate pharmacokinetics, pharmacodynamics and safety of etrolizumab in pediatric patients of 4 to <18 years of age with moderate to severe ulcerative colitis (UC) or with moderate to severe Crohn's disease (CD).
- Trial name
- FENNEL (NCT03478956)
- Testing
- Etrolizumab
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
HIV, Mental Health
Stepped Care for Youth Living With HIV
Optimizing the HIV Treatment Continuum with a Stepped Care Model for Youth Living with HIV (YLH) aims to achieve viral suppression among YLH.
- Conditions
- HIV, Mental Health, Illicit Substance Use, Sexually Transmitted Infections (STI)
- Trial name
- NCT03109431
- Testing
- Level 1, Level 2, Level 3
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dysmenorrhea
Efficacy and Safety Study of NPC-01 to Treat Dysmenorrhea
The purpose of this study is to determine whether NPC-01 is effective in the treatment of dysmenorrhea.
- Trial name
- NCT01129102
- Testing
- NPC-01, IKH-01
- Volunteers
- 215 people
- Sponsor
- Nobelpharma
Leukemia
Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia
RATIONALE: Giving chemotherapy before a donor stem cell transplant using stem cells that closely match the patient's stem cells, helps stop the growth of cancer cells.
- Trial name
- NCT00553202
- Testing
- anti-thymocyte globulin, busulfan, cyclophosphamide
- Where
- 52 sites in United States, Canada
- Volunteers
- 158 people
- Sponsor
- Children's Oncology Group
Low Back Pain, Postural; Strain
Mézières Therapy in the UCAM's Athletes With Low Back Pain
The purpose of this research study focuses on the re-harmonization of the kinetic chains and posture based on spinal muscular atrophy and global stretching while trying to test the effectiveness of Mézières therapy on sports…
- Trial name
- NCT03849053
- Testing
- Mézières Therapy for Low back pain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.