Clinical trials: Condition
Prostate Cancer
Safety and Efficacy of Irreversible Electroporation in Ablation of Prostate Cancer in Humans
Up to 16 patients with confirmed low- or intermediate risk prostate cancer scheduled for a radical prostatectomy will be asked to have the Irreversible Electroporation (IRE) procedure approximately 30 days prior to the…
- Trial name
- NCT01790451
- Testing
- Irreversible Electroporation
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Clinical Research Office of the Endourological Society
Spinal Muscular Atrophy Type I
Clinical Trial to Assess the Safety and Efficacy of EXG001-307 in Patients with Spinal Muscular Atrophy Type 1
The purpose of this trial is to evaluate safety and efficacy of intravenous delivery of EXG001-307 as a treatment of spinal muscular atrophy Type 1 (SMN1).
- Trial name
- NCT05614531
- Testing
- EXG001-307 injection
- Where
- 2 sites in China
- Volunteers
- 12 people
- Sponsor
- Guangzhou Jiayin Biotech Ltd
Glaucoma
Study of PGA Suture in Ophthalmology
To evaluate the safety and efficacy of polyglycolic acid suture in ophthalmic surgical procedures
- Trial name
- NCT00351429
- Testing
- Polyglycolic acid suture
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Aurolab
Metabolic Syndrome
Metabolic Syndrome Prevalence Study
Following the first study conducted to investigate the prevalence of metabolic syndrome and its components in Turkey, it was aimed to demonstrate the change in general health condition of available patients after the period of…
- Trial name
- NCT02379702
- Testing
- Metabolic Syndrome
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 1,659 people
- Sponsor
- Abdi Ibrahim Ilac San. ve Tic A.S.
Kidney Failure, Chronic, Kidney Transplantation
Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation
Kidney transplantation is widely considered to be the treatment of choice for children with End Stage Renal Disease (ESRD). The purpose of this study is to determine the safety of sirolimus monotherapy for long-term…
- Conditions
- Kidney Failure, Chronic, Kidney Transplantation, Immunosuppression
- Trial name
- NCT00768729
- Testing
- Sirolimus, MMF or Azathioprine
- Where
- 5 sites in United States
- Volunteers
- 7 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
SARS-CoV-2
A Study to Evaluate the Immunogenicity and Safety of Omicron Variant Vaccines in Comparison With mRNA-1273 Booster Vaccine for COVID-19
This is a 2-part study to evaluate the immunogenicity, safety, and reactogenicity of mRNA-1273.529 and mRNA-1273.214 administered as a booster dose.
- Trial name
- NCT05249829
- Testing
- mRNA-1273.529, mRNA-1273, mRNA-1273.214
- Where
- 29 sites in United Kingdom
- Volunteers
- 3,548 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Intracranial Neoplasm, Low Grade Glioma
Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms
This phase II trial studies how well F-18 fluoroethyltyrosine (fluoroethyltyrosine) works in detecting tumors in participants with intracranial tumors that have come back.
- Conditions
- Intracranial Neoplasm, Low Grade Glioma, Recurrent Glioblastoma, Recurrent World Health Organization (WHO) Grade II Glioma
- Trial name
- UC-GlioFET (NCT04044937)
- Testing
- F-18 Fluoroethyltyrosine (FET), Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Thomas Hope
Foreign Body Airway Obstruction
Prospective Evaluation of Foreign Body Airway Obstruction Interventions Among Adults and Children
Foreign body airway obstruction (FBAO, choking) is a life-threatening emergency requiring time-sensitive treatment to prevent severe injury or deaths.
- Trial name
- NCT07365137
- Testing
- Abdominal thrust, Back blows, Chest compressions/thrusts
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Calgary
Ischemic Bowel Disease
Clinical Application and Mechanism of Cord Blood Mononuclear Cells in the Treatment of Ischemic Bowel Disease
Ischemic bowel disease, also known as ischemic bowel disease (IBD), is a type of disease that causes the blood supply to a certain intestinal segment to be reduced or stopped by various reasons such as hypovolemia, shock or…
- Trial name
- NCT05560672
- Testing
- Human Umbilical Cord blood mononuclear cells
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qianfoshan Hospital
Autism Spectrum Disorder, Child Development Disorders, Pervasive
Trial of Therapeutic Horseback Riding in Children and Adolescents With Autism Spectrum Disorder
This study is being carried out to learn more about the effects of Therapeutic Horseback Riding (THR) for children and adolescents with an autism spectrum disorder (ASD).
- Trial name
- NCT02301195
- Testing
- Therapeutic horseback riding, Barn Activity Intervention
- Volunteers
- 209 people
- Sponsor
- University of Colorado, Denver
Dermatitis, Seborrheic, Dry Skin; Eczema
Safety and Efficacy of a Topical Scalp Treatment for Dry Scalp Conditions in Children and Adult
The purpose of this study is to evaluate the safety and efficacy of a novel topical treatment for dry scalp conditions, including dandruff, seborrheic dermatitis, and atopic dermatitis.
- Trial name
- NCT03830177
- Testing
- Natural Treatment
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Single-ventricle
Fibrosis and the Fontan
The purpose of this study is to non-invasively characterize the fibrotic consequences of single ventricle physiology, its possible solution and effect on lymphatics.
- Trial name
- NCT04901975
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Children's Hospital of Philadelphia
Prader-Willi Syndrome
Probiotic Treatment for Prader-Willi Syndrome
A whole new research area studying the function of intestinal microorganisms, also known as gut microbiota, has emerged during the last decade.
- Trial name
- NCT04685057
- Testing
- Probiotic, Follow-up probiotic
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Fundació Sant Joan de Déu
Allergic Conjunctivitis
Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in Allergic Conjunctivitis
The purpose of this study is to evaluate the efficacy and safety of an anti-allergy drug with a contact lens compared to placebo in preventing ocular itching associated with allergic conjunctivitis
- Trial name
- NCT00432757
- Testing
- Ketotifen with a Contact Lens (generic name not yet established)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Vistakon Pharmaceuticals
Covid19
Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population
COVID-19 infection coud induce cardiac injuries. Before returning to sport, cardiac evaluation is recommended by sports federations, based on the precautionary principle and the opinion of expert consensus.
- Trial name
- CADE (NCT04653857)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Eye Abnormalities
Modeling Ocular Developmental Diseases From 3D Cultures of Optic Vesicle Organoids Derived From hiPSCs of Patients With Ocular Malformations
Ocular morphogenesis is a complex process starting as early as the 4th week of embryonic life, involving interactions between varioustissues of different origin and conserved genes.
- Trial name
- OrganoEye (NCT06408701)
- Testing
- Blood sampling
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Pituitary Adenoma 1, Acth-Secreting
Pituitary Adenoma and Serum Lipid
Pituitary adenomas are usually benign monoclonal neoplasms caused by a mixture of pituicyte alterations together with a changed endocrine and paracrine regulatory milieu.
- Trial name
- NCT04021212
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shandong Provincial Hospital
DCM - Dilated Cardiomyopathy
Observational Study for Patients With Dilated Cardiomyopathy
Observational study on patients with dilated cardiomyopathy aims to investigate the correlation between cardiac fibrosis, as indicated by cardiac magnetic resonance, and the prognosis of patients with dilated cardiomyopathy, and…
- Trial name
- NCT04837612
- Testing
- No intervention nor exposure
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangdong Provincial People's Hospital
Undernutrition, Healthy Nutrition
Women Supporting Women to Improve Infant and Child Feeding Practices
Undernutrition in the first 2 years of life is the largest preventable cause of death before age 5. Among those who survive, stunting before age two leaves millions with lifelong physical and cognitive deficits, which are…
- Conditions
- Undernutrition, Healthy Nutrition, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05473312
- Testing
- Community Sensitization, 28-day PD/Hearth Sessions, Supplemental Print Information
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Aga Khan University
Severe Hemophilia A
Study to Investigate the Long-term Efficacy and Safety of Human-cl rhFVIII in Previously Treated Patients (PTPs)
The purpose of the study is to study the long-term efficacy, safety and tolerability of Human-cl rhFVIII in previously treated patients with severe hemophilia A.
- Trial name
- NCT01341912
- Testing
- Human-cl rhFVIII
- Where
- 2 sites in United States, Bulgaria
- Volunteers
- 3 people
- Sponsor
- Octapharma
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